Self recognition in allogeneic radiation bone marrow chimeras. A radiation-resistant host element dictates the self specificity and immune response gene phenotype of T-helper cells.
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Major histocompatibility restriction of antigen recognition by T cells in a recipient of haplotype mismatched human bone marrow transplantation.Self recognition in allogeneic thymic chimeras. Self recognition by T helper cells from thymus-engrafted nude mice is restricted to the thymic H-2 haplotype.Positive selection of a T-cell subpopulation in the thymus in which it develops.Heterogenous graft rejection pathways in class I major histocompatibility complex-disparate combinations and their differential susceptibility to immunomodulation induced by intravenous presensitization with relevant alloantigensTolerance of thymic cytotoxic T lymphocytes to allogeneic H-2 determinants encountered prethymically: evidence for expression of anti-H-2 receptors prior to entry into the thymusGeneration of the alloreactive T-cell repertoire: interaction of T-cell genotype and maturation environment.Interleukin 1 can replace the requirement for I-A-positive cells in the proliferation of antigen-primed T cells.Murine syngeneic mixed lymphocyte response. I. Target antigens are self Ia moleculesTolerance of thymocytes to allogeneic I region determinants encountered prethymically. Evidence for expression of anti-Ia receptors by T cell precursors before their entry into the thymus.Homologies between cell interaction molecular controlled by major histocompatibility complex- and Igh-V-linked genes that T cells use for communication. Tandem "adaptive" differentiation of producer and acceptor cellsMajor histocompatibility complex-restricted self-recognition in responses to trinitrophenyl-ficoll. Adaptive differentiation and self-recognition by B cellsCytotoxic T lymphocyte responses in allogeneic radiation bone marrow chimeras. The chimeric host strictly dictates the self-repertoire of Ia-restricted T cells but not H-2K/D-restricted T cellsAntigen-presenting cells from nonresponder strain 2 guinea pigs are fully competent to present bovine insulin B chain to responder strain 13 T cells. Evidence against a determinant selection model and in favor of a clonal deletion model of immune reRole of the H-2 complex in the induction of T cell tolerance to self minor histocompatibility antigens.Allosuppressor and allohelper T cells in acute and chronic graft-vs-host disease. V. F1 mice with secondary chronic GVHD contain F1-reactive allohelper but no allosuppressor T cells.Self-recognition specificity expressed by T cells from nude mice. Absence of detectable Ia-restricted T cells in nude mice that do exhibit self-K/D-restricted T cell responses.Characterization of mixed allogeneic chimeras. Immunocompetence, in vitro reactivity, and genetic specificity of tolerance.Both L3T4+ and Lyt-2+ helper T cells initiate cytotoxic T lymphocyte responses against allogenic major histocompatibility antigens but not against trinitrophenyl-modified selfCharacterization of antigen-specific, Ia-restricted, L3T4+ cytolytic T lymphocytes and assessment of thymic influence on their self specificity.A naturally occurring bone marrow-chimeric primate. II. Environment dictates restriction on cytolytic T lymphocyte-target cell interactions.Characterization of two distinct primary T cell populations that secrete interleukin 2 upon recognition of class I or class II major histocompatibility antigensEffects of T cell depletion in radiation bone marrow chimeras. II. Requirement for allogeneic T cells in the reconstituting bone marrow inoculum for subsequent resistance to breaking of tolerance.Antigen recognition by MHC-incompatible cells of a human mismatched chimera.Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen.Tolerization of anti-Galalpha1-3Gal natural antibody-forming B cells by induction of mixed chimerism.Innate and adaptive immune responses are tolerized in chimeras prepared with nonmyeloablative conditioningImmune tolerance: mechanisms and application in clinical transplantation.Stable mixed chimerism and tolerance using a nonmyeloablative preparative regimen in a large-animal model.Ia+ murine epidermal Langerhans cells are deficient in surface expression of the class I major histocompatibility complex.Bone marrow-derived thymic antigen-presenting cells determine self-recognition of Ia-restricted T lymphocytes.H-2-incompatible bone marrow chimeras produce donor-H-2-restricted Ly-2 suppressor T-cell factor(s).Influence of dimethyl myleran on tolerance induction and immune function in major histocompatibility complex-haploidentical murine bone-marrow transplantation.Translational studies in hematopoietic cell transplantation: treatment of hematologic malignancies as a stepping stone to tolerance induction.Recognition requirements for the activation, differentiation and function of T-helper cells specific for class I MHC alloantigens.T cell selection in the thymus.Ontogeny of primary lymphoid organs and lymphoid stem cells.Distinct B cell subpopulations differ in their genetic requirements for activation by T helper cells.Xenograft tolerance.The collaborative phenotype of secondary B cells is determined by T lymphocytes during in vivo immunization.Biochemical characterization of a second family of human Ia molecules, HLA-DS, equivalent to murine I-A subregion molecules
P2860
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P2860
Self recognition in allogeneic radiation bone marrow chimeras. A radiation-resistant host element dictates the self specificity and immune response gene phenotype of T-helper cells.
description
1981 nî lūn-bûn
@nan
1981年の論文
@ja
1981年学术文章
@wuu
1981年学术文章
@zh-cn
1981年学术文章
@zh-hans
1981年学术文章
@zh-my
1981年学术文章
@zh-sg
1981年學術文章
@yue
1981年學術文章
@zh
1981年學術文章
@zh-hant
name
Self recognition in allogeneic ...... e phenotype of T-helper cells.
@ast
Self recognition in allogeneic ...... e phenotype of T-helper cells.
@en
type
label
Self recognition in allogeneic ...... e phenotype of T-helper cells.
@ast
Self recognition in allogeneic ...... e phenotype of T-helper cells.
@en
prefLabel
Self recognition in allogeneic ...... e phenotype of T-helper cells.
@ast
Self recognition in allogeneic ...... e phenotype of T-helper cells.
@en
P2093
P2860
P356
P1476
Self recognition in allogeneic ...... e phenotype of T-helper cells.
@en
P2093
P2860
P304
P356
10.1084/JEM.153.5.1286
P407
P577
1981-05-01T00:00:00Z