Dual action of the inhibitors of cyclin-dependent kinases: targeting of the cell-cycle progression and activation of wild-type p53 protein.
about
Cyclin-dependent kinase activity controls the onset of the HCMV lytic cycleThe impact of CDK inhibition in human malignancies associated with pronounced defects in apoptosis: advantages of multi-targeting small molecules.Anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates as p53 activators in cervical cancer cells.The metabolic landscape of cancer stem cells.Can ex vivo evaluation (testing) predict the sensitivity of CLL cells to therapy with purine analogs in conjunction with an alkylating agent? A comparison of in vivo and ex vivo responses to treatment.Interference with ER-α enhances the therapeutic efficacy of the selective CDK inhibitor roscovitine towards ER-positive breast cancer cells.Reconstitution of human MCF-7 breast cancer cells with caspase-3 does not sensitize them to action of CDK inhibitors.Roscovitine synergizes with conventional chemo-therapeutic drugs to induce efficient apoptosis of human colorectal cancer cells.Effect of distinct anticancer drugs on the phosphorylation of p53 protein at serine 46 in human MCF-7 breast cancer cells.Prevention of p53 degradation in human MCF-7 cells by proteasome inhibitors does not mimic the action of roscovitine.Canine Mammary Carcinomas: A Comparative Analysis of Altered Gene Expression.The in Vitro and in Vivo Antitumor Activities of Tetracyclic Triterpenoids Compounds Actein and 26-Deoxyactein Isolated from Rhizome of Cimicifuga foetida L.
P2860
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P2860
Dual action of the inhibitors of cyclin-dependent kinases: targeting of the cell-cycle progression and activation of wild-type p53 protein.
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年學術文章
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name
Dual action of the inhibitors ...... tion of wild-type p53 protein.
@ast
Dual action of the inhibitors ...... tion of wild-type p53 protein.
@en
type
label
Dual action of the inhibitors ...... tion of wild-type p53 protein.
@ast
Dual action of the inhibitors ...... tion of wild-type p53 protein.
@en
prefLabel
Dual action of the inhibitors ...... tion of wild-type p53 protein.
@ast
Dual action of the inhibitors ...... tion of wild-type p53 protein.
@en
P2860
P356
P1476
Dual action of the inhibitors ...... tion of wild-type p53 protein.
@en
P2093
Gerald Schmid
P2860
P356
10.1517/13543784.15.1.23
P407
P577
2006-01-01T00:00:00Z