Protective antibody and CD8+ T-cell responses to the Plasmodium falciparum circumsporozoite protein induced by a nanoparticle vaccine
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The Use of Synthetic Carriers in Malaria Vaccine DesignMalaria vaccine based on self-assembling protein nanoparticlesEnhancing protective immunity to malaria with a highly immunogenic virus-like particle vaccine.Classification of self-assembling protein nanoparticle architectures for applications in vaccine designEffectiveness of a novel immunogenic nanoparticle platform for Toxoplasma peptide vaccine in HLA transgenic miceTransgenic parasites stably expressing full-length Plasmodium falciparum circumsporozoite protein as a model for vaccine down-selection in mice using sterile protection as an endpoint.IgG2 antibodies against a clinical grade Plasmodium falciparum CSP vaccine antigen associate with protection against transgenic sporozoite challenge in mice.Titrating T-cell epitopes within self-assembled vaccines optimizes CD4+ helper T cell and antibody outputsP. falciparum and P. vivax Epitope-Focused VLPs Elicit Sterile Immunity to Blood Stage Infections.Head-to-Head Comparison of Soluble vs. Qβ VLP Circumsporozoite Protein Vaccines Reveals Selective Enhancement of NANP Repeat Responses.Optimizing the design of protein nanoparticles as carriers for vaccine applicationsSupramolecular peptide vaccines: tuning adaptive immunity.Particle-based platforms for malaria vaccines.Principles Governing the Self-Assembly of Coiled-Coil Protein NanoparticlesDevelopment of a Plasmodium berghei transgenic parasite expressing the full-length Plasmodium vivax circumsporozoite VK247 protein for testing vaccine efficacy in a murine modelMechanisms of protective immune responses induced by the Plasmodium falciparum circumsporozoite protein-based, self-assembling protein nanoparticle vaccine.Applications of nanomaterials as vaccine adjuvants.The prediction of T- and B-combined epitope and tertiary structure of the Eg95 antigen of Echinococcus granulosusThe biodistribution of self-assembling protein nanoparticles shows they are promising vaccine platformsBacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses.Engaging adaptive immunity with biomaterialsApplications of nanotechnology for immunology.Small Wonders-The Use of Nanoparticles for Delivering Antigen.Design of nanomaterial based systems for novel vaccine development.Vaccine technologies: From whole organisms to rationally designed protein assemblies.Self-assembling peptide-based building blocks in medical applications.Role of Metallic Nanoparticles in Vaccinology: Implications for Infectious Disease Vaccine Development.The use of a P. falciparum specific coiled-coil domain to construct a self-assembling protein nanoparticle vaccine to prevent malaria.Expression, purification and refolding of a self-assembling protein nanoparticle (SAPN) malaria vaccine.Self-assembling protein nanoparticles: a promising tool against lethal influenza?Report from the field: Overview of the Sixth Annual Vaccine Renaissance ConferenceThe use of self-adjuvanting nanofiber vaccines to elicit high-affinity B cell responses to peptide antigens without inflammation.Protein nanovaccine confers robust immunity against Toxoplasma.MyD88 in antigen-presenting cells is not required for CD4+ T-cell responses during peptide nanofiber vaccinationA self-adjuvanted nanoparticle based vaccine against infectious bronchitis virus
P2860
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P2860
Protective antibody and CD8+ T-cell responses to the Plasmodium falciparum circumsporozoite protein induced by a nanoparticle vaccine
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Protective antibody and CD8+ T ...... uced by a nanoparticle vaccine
@ast
Protective antibody and CD8+ T ...... uced by a nanoparticle vaccine
@en
type
label
Protective antibody and CD8+ T ...... uced by a nanoparticle vaccine
@ast
Protective antibody and CD8+ T ...... uced by a nanoparticle vaccine
@en
prefLabel
Protective antibody and CD8+ T ...... uced by a nanoparticle vaccine
@ast
Protective antibody and CD8+ T ...... uced by a nanoparticle vaccine
@en
P2093
P2860
P1433
P1476
Protective antibody and CD8+ T ...... uced by a nanoparticle vaccine
@en
P2093
Christian Mittelholzer
Clara Brando
David E Lanar
Debleena Dasgupta
Margaret E McCoy
Peter Burkhard
Roberta Spaccapelo
Stephen A Kaba
Tais A P F Doll
P2860
P304
P356
10.1371/JOURNAL.PONE.0048304
P407
P577
2012-10-29T00:00:00Z