Genotypic analysis of B cell colonies by in situ hybridization. Stoichiometric expression of three VH families in adult C57BL/6 and BALB/c mice.
about
Analysis of the expression immunoglobulin gene repertoire by screening libraries derived from PCR-amplified cDNA.Most peripheral B cells in mice are ligand selected.Molecular cloning of the primary IgH repertoire: a quantitative analysis of VH gene usage in adult miceStochastic pairing of heavy-chain and kappa light-chain variable gene families occurs in polyclonally activated B cellsPreferential rearrangement of V kappa 4 gene segments in pre-B cell lines.In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations.Mouse variable-region gene families: complexity, polymorphism and use in non-autoimmune responses.Characterization of the immunoglobulin heavy chain complementarity determining region (CDR)-III sequences from human B cell precursor acute lymphoblastic leukemia cells.The genomic organization of immunoglobulin VH genes in Xenopus laevis shows evidence for interspersion of familiesExpression of V gene families during ontogeny and establishment of B cell repertoire.Comparative expression of adult and fetal V gene repertoires.VH gene family expression in mice with the xid defectSelection of antigen-specific, idiotype-positive B cells in transgenic mice expressing a rearranged M167-mu heavy chain gene.Clonal analysis of a human antibody response. II. Sequences of the VH genes of human IgM, IgG, and IgA to rabies virus reveal preferential utilization of VHIII segments and somatic hypermutationBiased expression of JH-proximal VH genes occurs in the newly generated repertoire of neonatal and adult mice.Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences.Developmentally regulated and strain-specific expression of murine VH gene families.Comparison of the fetal and adult functional B cell repertoires by analysis of VH gene family expression.The organization of the mouse Igh-V locus. Dispersion, interspersion, and the evolution of VH gene family clusters.Sequence of the spacer in the recombination signal sequence affects V(D)J rearrangement frequency and correlates with nonrandom Vkappa usage in vivoChromosomal position of rearranging gene segments influences allelic exclusion in transgenic mice.The past, present, and future of immune repertoire biology - the rise of next-generation repertoire analysis.Structural correlates of a regulatory idiotope.Anti-DNA antibodies, autoimmunity and the immunoglobulin repertoire.The molecular origin of regulatory idiotypes.Murine V kappa gene expression does not follow the VH paradigmVH gene family utilization is regulated by a locus outside of the VH region.The primary antibody repertoire of kappa-deficient mice is characterized by non-stochastic Vlamda1 + V(H) gene family pairings and a higher degree of self-reactivity.VH-gene family dominance in ageing mice.
P2860
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P2860
Genotypic analysis of B cell colonies by in situ hybridization. Stoichiometric expression of three VH families in adult C57BL/6 and BALB/c mice.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh
1987年學術文章
@zh-hant
name
Genotypic analysis of B cell c ...... adult C57BL/6 and BALB/c mice.
@ast
Genotypic analysis of B cell c ...... adult C57BL/6 and BALB/c mice.
@en
type
label
Genotypic analysis of B cell c ...... adult C57BL/6 and BALB/c mice.
@ast
Genotypic analysis of B cell c ...... adult C57BL/6 and BALB/c mice.
@en
prefLabel
Genotypic analysis of B cell c ...... adult C57BL/6 and BALB/c mice.
@ast
Genotypic analysis of B cell c ...... adult C57BL/6 and BALB/c mice.
@en
P2860
P356
P1476
Genotypic analysis of B cell c ...... adult C57BL/6 and BALB/c mice.
@en
P2093
P2860
P304
P356
10.1084/JEM.166.1.163
P407
P577
1987-07-01T00:00:00Z