Clonal analysis of a human antibody response. II. Sequences of the VH genes of human IgM, IgG, and IgA to rabies virus reveal preferential utilization of VHIII segments and somatic hypermutation
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Novel rabies virus-neutralizing epitope recognized by human monoclonal antibody: fine mapping and escape mutant analysis.Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphomaTeleost fish mount complex clonal IgM and IgT responses in spleen upon systemic viral infectionThe HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3' hs1,2 enhancer in human B cells. Relevance to class switch DNA recombinationVH3 gene usage in neutralizing human antibodies specific for the Entamoeba histolytica Gal/GalNAc lectin heavy subunitSelection of single chain variable fragments (scFv) against the glycoprotein antigen of the rabies virus from a human synthetic scFv phage display library and their fusion with the Fc region of human IgG1.Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome.Generation of a neutralizing human monoclonal antibody Fab fragment to surface antigen 1 of Toxoplasma gondii tachyzoites.Evidence that the V kappa III gene usage is nonstochastic in both adult and newborn peripheral B cells and that peripheral CD5+ adult B cells are oligoclonal.Analysis of human monoclonal antibodies elicited by vaccination with a Cryptococcus neoformans glucuronoxylomannan capsular polysaccharide vaccine.Ethnic differences of polymorphism of an immunoglobulin VH3 gene.Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: definition of the requirements and modalities of hypermutation.Structure-function analysis of a lupus anti-DNA autoantibody: central role of the heavy chain complementarity-determining region 3 Arg in binding of double- and single-stranded DNA.Human rheumatoid B-1a (CD5+ B) cells make somatically hypermutated high affinity IgM rheumatoid factorsStructure of the VH and VL segments of monoreactive and polyreactive IgA autoantibodies to DNA in patients with systemic lupus erythematosusThe translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation.Structure of the VH and VL segments of polyreactive and monoreactive human natural antibodies to HIV-1 and Escherichia coli beta-galactosidaseLupus-specific antibodies reveal an altered pattern of somatic mutationGeneration of Human Monoclonal Autoantibody-Producing Cell Lines by Epstein-Barr Virus Transformation of Autoreactive B Lymphocytes and by Somatic Cell Hybridization Techniques: Application to the Analysis of the Autoimmune B Cell Repertoire.Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEmu enhancer and 3'Ealpha enhancers in human lymphoblastoid B cells.The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement.Molecular structure of eight human autoreactive monoclonal antibodies.VHDJH gene sequences and antigen reactivity of monoclonal antibodies produced by human B-1 cells: evidence for somatic selection.Two acquired immunodeficiency syndrome-associated Burkitt's lymphomas produce specific anti-i IgM cold agglutinins using somatically mutated VH4-21 segments.VH and V kappa segment structure of anti-insulin IgG autoantibodies in patients with insulin-dependent diabetes mellitus. Evidence for somatic selection.Structural analysis of the VH-D-JH segments of human polyreactive IgG mAb. Evidence for somatic selection.Generation of human monoclonal antibodies by transformation of lymphoblastoid B cells with ras oncogene.Characterization of Entamoeba histolytica intermediate subunit lectin-specific human monoclonal antibodies generated in transgenic mice expressing human immunoglobulin loci.Analysis of the structural correlates for antibody polyreactivity by multiple reassortments of chimeric human immunoglobulin heavy and light chain V segments.Lack of intraclonal diversification in Ig heavy and light chain V region genes expressed by CD5+IgM+ chronic lymphocytic leukemia B cells: a multiple time point analysisVariable region gene analysis of B cell subsets derived from a 4-year-old child: somatically mutated memory B cells accumulate in the peripheral blood already at young age.Age-related accumulation of Ig V(H) gene somatic mutations in peripheral B cells from aged humans.
P2860
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P2860
Clonal analysis of a human antibody response. II. Sequences of the VH genes of human IgM, IgG, and IgA to rabies virus reveal preferential utilization of VHIII segments and somatic hypermutation
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Clonal analysis of a human ant ...... ents and somatic hypermutation
@ast
Clonal analysis of a human ant ...... ents and somatic hypermutation
@en
type
label
Clonal analysis of a human ant ...... ents and somatic hypermutation
@ast
Clonal analysis of a human ant ...... ents and somatic hypermutation
@en
prefLabel
Clonal analysis of a human ant ...... ents and somatic hypermutation
@ast
Clonal analysis of a human ant ...... ents and somatic hypermutation
@en
P2093
P2860
P1476
Clonal analysis of a human ant ...... ents and somatic hypermutation
@en
P2093
A L Notkins
H Ikematsu
N Harindranath
P2860
P304
P407
P577
1993-02-01T00:00:00Z