Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes.
about
Ca2+ signaling modulates cytolytic T lymphocyte effector functions.Imaging effector functions of human cytotoxic CD4+ T cells specific for Plasmodium falciparum circumsporozoite protein.Molecular dynamics in the membranes of helper T cells.Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction: manifestation of a dual activation thresholdTargeted calcium influx boosts cytotoxic T lymphocyte function in the tumour microenvironment.Lipid-dependent cytotoxicity by the lipase PLRP2 and by PLRP2-positive cytotoxic T lymphocytes (CTLs).MicroRNA-150 modulates intracellular Ca 2+ levels in naïve CD8+ T cells by targeting TMEM20.Extracellular ATP in T-lymphocyte activation: possible role in effector functions.Shouts, whispers and the kiss of death: directional secretion in T cellsBlockade of Kv1.3 potassium channels inhibits differentiation and granzyme B secretion of human CD8+ T effector memory lymphocytes.Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cellsORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysisHostile, hypoxia-A2-adenosinergic tumor biology as the next barrier to overcome for tumor immunologistsGranzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes.Lymphocyte calcium signaling from membrane to nucleus.Interleukin 2 induction of pore-forming protein gene expression in human peripheral blood CD8+ T cells.CD8(+) T cell tolerance to a tumor-associated antigen is maintained at the level of expansion rather than effector function.Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers.Human T cell specific proteinase (HuTSP) is encoded by the T cell and natural killer cell specific human Hanukah factor (HuHF) gene.Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation.Ion channels in innate and adaptive immunityERK activation is only one role of PKC in TCR-independent cytotoxic T cell granule exocytosisRegulation of lymphocyte function by ORAI and STIM proteins in infection and autoimmunity.Building tolerance by dismantling synapses: inhibitory receptor signaling in natural killer cells.The C2A domain of synaptotagmin-like protein 3 (Slp3) is an atypical calcium-dependent phospholipid-binding machine: comparison with the C2A domain of synaptotagmin I.The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune systemMechanistic, functional and immunopharmacological implications of biochemical studies of antigen receptor-triggered cytolytic T-lymphocyte activation.Perforin-dependent and -independent pathways of cytotoxicity mediated by lymphocytes.Possible involvement of CTL granule proteases in target cell DNA breakdown.PELs and the perforin and granzyme independent mechanism of CTL-mediated lysis.Exocytic responses of single leukaemic human cytotoxic T lymphocytes stimulated by agents that bypass the T cell receptor.Interactions of the allogeneic effector leukemic T cell line, TALL-104, with human malignant brain tumors.Cross-talk with Ca(2+) influx does not underlie the role of extracellular signal-regulated kinases in cytotoxic T lymphocyte lytic granule exocytosis.Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor ImmunityInteraction of lymphokine-activated killer cells with susceptible targets does not induce second messenger generation and cytolytic granule exocytosis.Inhibitory receptor signaling destabilizes immunological synapse formation in primary NK cells.Increased levels of T cell granzyme b in bronchiolitis obliterans syndrome are not suppressed adequately by current immunosuppressive regimens.Cytotoxic granule endocytosis depends on the Flower protein.A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity.Calcineurin activation is only one calcium-dependent step in cytotoxic T lymphocyte granule exocytosis.
P2860
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P2860
Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh
1987年學術文章
@zh-hant
name
Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes.
@ast
Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes.
@en
type
label
Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes.
@ast
Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes.
@en
prefLabel
Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes.
@ast
Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes.
@en
P2860
P921
P356
P1476
Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes.
@en
P2093
Sitkovsky MV
Takayama H
P2860
P304
P356
10.1084/JEM.166.3.725
P407
P577
1987-09-01T00:00:00Z