Organ-specific selection of viral variants during chronic infection
about
Estimating the precursor frequency of naive antigen-specific CD8 T cellsMolecular analysis of neurovirulent strains of Sindbis virus that evolve during persistent infection of scid miceTiming of CD8 T cell effector responses in viral infectionsType I interferon suppresses virus-specific B cell responses by modulating CD8(+) T cell differentiationType I interferon is a therapeutic target for virus-induced lethal vascular damage.Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination.Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustionPosttranslational modification of alpha-dystroglycan, the cellular receptor for arenaviruses, by the glycosyltransferase LARGE is critical for virus binding.Host factors influencing viral persistence.LCMV glycosylation modulates viral fitness and cell tropism.Decoding arenavirus pathogenesis: essential roles for alpha-dystroglycan-virus interactions and the immune response.The role of dendritic cells in viral persistenceArenavirus variations due to host-specific adaptation.Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment.GITR intrinsically sustains early type 1 and late follicular helper CD4 T cell accumulation to control a chronic viral infection.Lymphocytic choriomeningitis virus persistence promotes effector-like memory differentiation and enhances mucosal T cell distributionImmunotherapeutic effects of IL-7 during a chronic viral infection in mice.Opposing effects of CD70 costimulation during acute and chronic lymphocytic choriomeningitis virus infection of miceExpanded potential for recombinant trisegmented lymphocytic choriomeningitis viruses: protein production, antibody production, and in vivo assessment of biological function of genes of interest.Infection of dendritic cells by lymphocytic choriomeningitis virus.Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infectionBlockade of interferon Beta, but not interferon alpha, signaling controls persistent viral infectionDNA vaccination against persistent viral infection.Brain- and intestine-specific variants of reovirus serotype 3 strain dearing are selected during chronic infection of severe combined immunodeficient miceClearance of an immunosuppressive virus from the CNS coincides with immune reanimation and diversification.Competitive selection in vivo by a cell for one variant over another: implications for RNA virus quasispecies in vivo.CD4 T Cell Depletion Substantially Augments the Rescue Potential of PD-L1 Blockade for Deeply Exhausted CD8 T Cells.Uncovering subdominant cytotoxic T-lymphocyte responses in lymphocytic choriomeningitis virus-infected BALB/c mice.Lassa virus.Infection of lymphocytes by a virus that aborts cytotoxic T lymphocyte activity and establishes persistent infection.Immunosuppression and resultant viral persistence by specific viral targeting of dendritic cellsGeneration and maintenance of Listeria-specific CD8+ T cell responses in perforin-deficient mice chronically infected with LCMVAlternative serotype adenovirus vaccine vectors elicit memory T cells with enhanced anamnestic capacity compared to Ad5 vectorsCD8 T cell defect of TNF-α and IL-2 in DNAM-1 deficient mice delays clearance in vivo of a persistent virus infectionVirus-induced immunosuppression: kinetic analysis of the selection of a mutation associated with viral persistenceTissue-mediated selection of viral variants: correlation between glycoprotein mutation and growth in neuronal cells.Molecular determinants of macrophage tropism and viral persistence: importance of single amino acid changes in the polymerase and glycoprotein of lymphocytic choriomeningitis virusMolecular anatomy of viral persistenceDerivation of neurotropic simian immunodeficiency virus from exclusively lymphocytetropic parental virus: pathogenesis of infection in macaquesPD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis
P2860
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P2860
Organ-specific selection of viral variants during chronic infection
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
@zh
1988年學術文章
@zh-hant
name
Organ-specific selection of viral variants during chronic infection
@ast
Organ-specific selection of viral variants during chronic infection
@en
type
label
Organ-specific selection of viral variants during chronic infection
@ast
Organ-specific selection of viral variants during chronic infection
@en
prefLabel
Organ-specific selection of viral variants during chronic infection
@ast
Organ-specific selection of viral variants during chronic infection
@en
P2860
P356
P1476
Organ-specific selection of viral variants during chronic infection
@en
P2093
P2860
P304
P356
10.1084/JEM.167.5.1719
P407
P577
1988-05-01T00:00:00Z