Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy - Wikidata - awgldk - TriplyDB

Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy

Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy

http://www.wikidata.org/entity/Q36358042

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Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth Protein kinase cascades in the regulation of cardiac hypertrophy PLIP, a novel splice variant of Tip60, interacts with group IV cytosolic phospholipase A(2), induces apoptosis, and potentiates prostaglandin production Histone deacetylase signaling in cardioprotection miR-9 and NFATc3 regulate myocardin in cardiac hypertrophy Mechanical stretch up-regulates microRNA-26a and induces human airway smooth muscle hypertrophy by suppressing glycogen synthase kinase-3β Myostatin regulates cardiomyocyte growth through modulation of Akt signaling The GSK-3 family as therapeutic target for myocardial diseases Molecular basis of physiological heart growth: fundamental concepts and new players The cell biology of disease: cellular mechanisms of cardiomyopathy.Cardiac Troponin and Tropomyosin: Structural and Cellular Perspectives to Unveil the Hypertrophic Cardiomyopathy Phenotype Stabilization of beta-catenin by a Wnt-independent mechanism regulates cardiomyocyte growth Mood stabilizers, glycogen synthase kinase-3beta and cell survival The beta-catenin/T-cell factor/lymphocyte enhancer factor signaling pathway is required for normal and stress-induced cardiac hypertrophy Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo The pro-hypertrophic basic helix-loop-helix protein p8 is degraded by the ubiquitin/proteasome system in a protein kinase B/Akt- and glycogen synthase kinase-3-dependent manner, whereas endothelin induction of p8 mRNA and renal mesangial cell hypert Angiotensin-II type 1 receptor and NOX2 mediate TCF/LEF and CREB dependent WISP1 induction and cardiomyocyte hypertrophy Inhibition of glycogen synthase kinase 3[beta] activity with lithium in vitro attenuates sepsis-induced changes in muscle protein turnover Glycogen synthase kinase 3 alpha and 3 beta have distinct functions during cardiogenesis of zebrafish embryo.Deletion of CXCR4 in cardiomyocytes exacerbates cardiac dysfunction following isoproterenol administration Toward transcriptional therapies for the failing heart: chemical screens to modulate genes Direct and indirect interactions between calcineurin-NFAT and MEK1-extracellular signal-regulated kinase 1/2 signaling pathways regulate cardiac gene expression and cellular growth.TEAD-1 overexpression in the mouse heart promotes an age-dependent heart dysfunction.Regulation of calcineurin through transcriptional induction of the calcineurin A beta promoter in vitro and in vivo.Glycogen synthase kinase-3beta regulates post-myocardial infarction remodeling and stress-induced cardiomyocyte proliferation in vivo Influence of gestational overfeeding on cardiac morphometry and hypertrophic protein markers in fetal sheep Motility, survival, and proliferation.Constitutive glycogen synthase kinase-3alpha/beta activity protects against chronic beta-adrenergic remodelling of the heart.Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes.β-Adrenergic receptor-PI3K signaling crosstalk in mouse heart: elucidation of immediate downstream signaling cascades.Mouse DTEF-1 (ETFR-1, TEF-5) is a transcriptional activator in alpha 1-adrenergic agonist-stimulated cardiac myocytes.Myocardial stress remodelling after regional infarction is independent of glycogen synthase kinase-3 inactivation.Soy diet worsens heart disease in mice.Akt/protein kinase B promotes organ growth in transgenic mice.Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals The FOXO3a transcription factor regulates cardiac myocyte size downstream of AKT signaling.Glucose phosphorylation is required for insulin-dependent mTOR signalling in the heart.Calcineurin and cardiac hypertrophy: where have we been? Where are we going?

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Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy

http://www.wikidata.org/entity/Q36358042

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2000 nî lūn-bûn

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Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy

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Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy

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Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy

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Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy

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Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy

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Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy

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A Alessandrini

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A Michael

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A Rosenzweig

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G Choukroun

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H Ranu

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J D Molkentin

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R Hajjar

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S Haq

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T Matsui

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Z B Kang

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P2860

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation

A molecular mechanism for the effect of lithium on development

A simplified system for generating recombinant adenoviruses

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT

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117-130

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10.1083/JCB.151.1.117

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1

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151

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James R. Woodgett

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237688868

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11018058

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