DNA damage, cellular senescence and organismal ageing: causal or correlative? - Wikidata - awgldk - TriplyDB

DNA damage, cellular senescence and organismal ageing: causal or correlative?

DNA damage, cellular senescence and organismal ageing: causal or correlative?

http://www.wikidata.org/entity/Q36360646

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Replicative senescence induced by Romo1-derived reactive oxygen species Forever young: mechanisms of natural anoxia tolerance and potential links to longevity Inflammation & autoimmunity in human ageing: dendritic cells take a center stage Growing Old is Mandatory But Growing Up is Optional: An Explanation to Geriatrics A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency Accelerated senescence in kidneys of low-birth-weight rats after catch-up growth High-Fidelity Reprogrammed Human IPSCs Have a High Efficacy of DNA Repair and Resemble hESCs in Their MYC Transcriptional Signature Early developmental conditioning of later health and disease: physiology or pathophysiology?Sex-related differences in length and erosion dynamics of human telomeres favor females.Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1.Age-associated epigenetic modifications in human DNA increase its immunogenicity.Ginsenoside Rg1 enhances the resistance of hematopoietic stem/progenitor cells to radiation-induced aging in mice.RETRACTED: DDB2, an essential mediator of premature senescence Antioxidant defenses predict long-term survival in a passerine bird Premature aging and cancer in nucleotide excision repair-disorders.Influence of aerobic fitness on age-related lymphocyte DNA damage in humans: relationship with mitochondria respiratory chain and hydrogen peroxide production MicroRNA (miRNA)-mediated interaction between leukemia/lymphoma-related factor (LRF) and alternative splicing factor/splicing factor 2 (ASF/SF2) affects mouse embryonic fibroblast senescence and apoptosis Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation.Immortalization of MEF is characterized by the deregulation of specific miRNAs with potential tumor suppressor activity Fragile DNA repair mechanism reduces ageing in multicellular model.Testosterone in newly diagnosed, antipsychotic-naive men with nonaffective psychosis: a test of the accelerated aging hypothesis.Association between telomere length, specific causes of death, and years of healthy life in health, aging, and body composition, a population-based cohort study.The ATM cofactor ATMIN protects against oxidative stress and accumulation of DNA damage in the aging brain.The aging signature: a hallmark of induced pluripotent stem cells?Obesity accelerates epigenetic aging of human liver.Epigenetic age analysis of children who seem to evade aging.Evaluation of telomere length in cumulus cells as a potential biomarker of oocyte and embryo quality.Culturing on Wharton's jelly extract delays mesenchymal stem cell senescence through p53 and p16INK4a/pRb pathways Resveratrol induces premature senescence in lung cancer cells via ROS-mediated DNA damage.Long noncoding RNAs(lncRNAs) and the molecular hallmarks of aging.Aging and insulin signaling differentially control normal and tumorous germline stem cells.Human stem cell aging: do mitochondrial DNA mutations have a causal role?p53, oxidative stress, and aging Telomeric aging: mitotic clock or stress indicator?Modulation of PPARγ provides new insights in a stress induced premature senescence model.Early-life origins of type 2 diabetes: fetal programming of the beta-cell mass.No evidence of elevated germline mutation accumulation under oxidative stress in Caenorhabditis elegans.Reversibility of replicative senescence in Saccharomyces cerevisiae: effect of homologous recombination and cell cycle checkpoints.Telomere Fragment Induced Amnion Cell Senescence: A Contributor to Parturition?DNA double-strand break repair is impaired in presenescent Syrian hamster fibroblasts

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P2860

DNA damage, cellular senescence and organismal ageing: causal or correlative?

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2007 nî lūn-bûn

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Free radicals and antioxidants in normal physiological functions and human disease

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Superoxide dismutase 1 knock-down induces senescence in human fibroblasts

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

High-quality life extension by the enzyme peptide methionine sulfoxide reductase

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