B lymphocytes may escape tolerance by revising their antigen receptors
about
A role for MHC class II antigen processing in B cell development.Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switchingLack of allelic exclusion in B cell chronic lymphocytic leukemiaThe Role of Alternative Splicing in the Control of Immune Homeostasis and Cellular DifferentiationDefects in Germinal Center Selection in SLEImmunological aspects in chronic lymphocytic leukemia (CLL) developmentPrimary immunoglobulin repertoire development: time and space matterB cell receptor editing in tolerance and autoimmunityReceptor editing is the main mechanism of B cell tolerance toward membrane antigensLight chain editors of anti-DNA receptors in human B cellsSecondary rearrangements and hypermutation generate sufficient B cell diversity to mount protective antiviral immunoglobulin responses.Immunoglobulin heavy chain variable region gene replacement As a mechanism for receptor revision in rheumatoid arthritis synovial tissue B lymphocytesAnalysis of RAG expression by peripheral blood CD5+ and CD5- B cells of patients with childhood systemic lupus erythematosusConserved cryptic recombination signals in Vkappa gene segments are cleaved in small pre-B cells.Two distinct populations of H chain-edited B cells show differential surrogate L chain dependence.Receptor revision of immunoglobulin heavy chain variable region genes in normal human B lymphocytes.Receptor selection in B and T lymphocytes.Revising B cell receptorsAn in depth analysis of the concept of "polyspecificity" assumed to characterize TCR/BCR recognitionStructural basis for autoantibody recognition of phosphatidylserine-beta 2 glycoprotein I and apoptotic cellsExpansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency.Deletion of immunoglobulin beta in developing B cells leads to cell death.Mislocalization of SLP-76 leads to aberrant inflammatory cytokine and autoantibody productionCentral B-cell tolerance: where selection begins.B-cell-lineage immunogen design in vaccine development with HIV-1 as a case studyA stepwise epigenetic process controls immunoglobulin allelic exclusion.Donor-specific B-cell tolerance after ABO-incompatible infant heart transplantation.Receptor editing in lymphocyte development and central tolerance.Analysis of expressed and non-expressed IGK locus rearrangements in chronic lymphocytic leukemia.Induction of tolerance in arthritogenic B cells with receptors of differing affinity for self-antigen.Receptor revision and systemic lupus.Light chain inclusion permits terminal B cell differentiation and does not necessarily result in autoreactivity.B cell receptor light chain repertoires show signs of selection with differences between groups of healthy individuals and SLE patients.Alternative mechanisms of receptor editing in autoreactive B cells.Consequences of receptor editing at the lambda locus: multireactivity and light chain secretion.Enforced expression of the apoptosis inhibitor Bcl-2 ablates tolerance induction in DNA-reactive B cells through a novel mechanismDiverse immunoglobulin light chain organizations in fish retain potential to revise B cell receptor specificitiesViolation of an evolutionarily conserved immunoglobulin diversity gene sequence preference promotes production of dsDNA-specific IgG antibodies.B cell receptor expression level determines the fate of developing B lymphocytes: receptor editing versus selection.TLR7 influences germinal center selection in murine SLE.
P2860
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P2860
B lymphocytes may escape tolerance by revising their antigen receptors
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
B lymphocytes may escape tolerance by revising their antigen receptors
@ast
B lymphocytes may escape tolerance by revising their antigen receptors
@en
type
label
B lymphocytes may escape tolerance by revising their antigen receptors
@ast
B lymphocytes may escape tolerance by revising their antigen receptors
@en
prefLabel
B lymphocytes may escape tolerance by revising their antigen receptors
@ast
B lymphocytes may escape tolerance by revising their antigen receptors
@en
P2093
P2860
P356
P1476
B lymphocytes may escape tolerance by revising their antigen receptors
@en
P2093
P2860
P304
P356
10.1084/JEM.177.4.1165
P407
P50
P577
1993-04-01T00:00:00Z