Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells.
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Txk, a nonreceptor tyrosine kinase of the Tec family, is expressed in T helper type 1 cells and regulates interferon gamma production in human T lymphocytesRegulation of a cell type-specific silencer in the human iInterleukin-3 gene promoter by the transcription factor YY1 and an AP2 sequence-recognizing factorScurfin (FOXP3) acts as a repressor of transcription and regulates T cell activationMolecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoterT-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-gamma promoter via a conserved T-box half-siteCell fate decision: T-helper 1 and 2 subsets in immune responses.Role of transcriptional repressor ICER in cyclic AMP-mediated attenuation of cytokine gene expression in human thymocytesSelective induction of p38 mitogen-activated protein kinase activity following A6H co-stimulation in primary human CD4(+) T cells.Decreased immediate inflammatory gene induction in activating transcription factor-2 mutant mice.IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production.Ikaros silences T-bet expression and interferon-gamma production during T helper 2 differentiation.Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-gamma) promoter and subsequent downregulation of IFN-gamma production.ESAT-6 inhibits production of IFN-gamma by Mycobacterium tuberculosis-responsive human T cellsInterferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathwayCREB is a positive transcriptional regulator of gamma interferon in latent but not active tuberculosis infections.Regulation of nuclear gamma interferon gene expression by interleukin 12 (IL-12) and IL-2 represents a novel form of posttranscriptional control.Control of T helper cell differentiation--in search of master genes.Exposure to cigarette smoke inhibits the pulmonary T-cell response to influenza virus and Mycobacterium tuberculosis.PPAR activators as antiinflammatory mediators in human T lymphocytes: implications for atherosclerosis and transplantation-associated arteriosclerosis.Inhibition of IFN-gamma transcription by site-specific methylation during T helper cell development.Identification of a DNA binding site for the nuclear factor YY1 in the human GM-CSF core promoter.CCAAT/enhancer-binding protein α negatively regulates IFN-γ expression in T cells.A functional SNP of interferon-gamma gene is important for interferon-alpha-induced and spontaneous recovery from hepatitis C virus infectionOct1 and OCA-B are selectively required for CD4 memory T cell functionInterleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4Cytokine transcriptional events during helper T cell subset differentiation.The Ets transcription factor ERM is Th1-specific and induced by IL-12 through a Stat4-dependent pathway.ATF3 regulates MCMV infection in mice by modulating IFN-gamma expression in natural killer cells.Characterization of the human granulocyte-macrophage colony-stimulating factor gene promoter: an AP1 complex and an Sp1-related complex transactivate the promoter activity that is suppressed by a YY1 complex.The nuclear factor YY1 suppresses the human gamma interferon promoter through two mechanisms: inhibition of AP1 binding and activation of a silencer element.Biosynthesis and N-glycosylation of human interferon-gamma. Asn25 and Asn97 differ markedly in how efficiently they are glycosylated and in their oligosaccharide composition.CREB, ATF, and AP-1 transcription factors regulate IFN-gamma secretion by human T cells in response to mycobacterial antigen.Evolutionarily conserved sequence elements that positively regulate IFN-gamma expression in T cells.Interleukin-13 gene expression is regulated by GATA-3 in T cells: role of a critical association of a GATA and two GATG motifs.GATA-3 dominant negative mutant. Functional redundancy of the T cell receptor alpha and beta enhancers.DIM stimulates IFNgamma gene expression in human breast cancer cells via the specific activation of JNK and p38 pathways.Utilization of an NF-ATp binding promoter element for EGR3 expression in T cells but not fibroblasts provides a molecular model for the lymphoid cell-specific effect of cyclosporin A.Changes in epigenetic regulation of CD4+ T lymphocytesin biliary atresia.Activation of nuclear factor of activated T cells in a cyclosporin A-resistant pathway.Regulation of IFN-γ Expression.
P2860
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P2860
Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Two essential regulatory eleme ...... pecific expression in T cells.
@ast
Two essential regulatory eleme ...... pecific expression in T cells.
@en
type
label
Two essential regulatory eleme ...... pecific expression in T cells.
@ast
Two essential regulatory eleme ...... pecific expression in T cells.
@en
prefLabel
Two essential regulatory eleme ...... pecific expression in T cells.
@ast
Two essential regulatory eleme ...... pecific expression in T cells.
@en
P2093
P2860
P356
P1476
Two essential regulatory eleme ...... pecific expression in T cells.
@en
P2093
P2860
P304
P356
10.1084/JEM.178.5.1483
P407
P577
1993-11-01T00:00:00Z