Sulfation-dependent recognition of high endothelial venules (HEV)-ligands by L-selectin and MECA 79, and adhesion-blocking monoclonal antibody
about
Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectinMolecular cloning and functional analysis of SUT-1, a sulfate transporter from human high endothelial venulesGolgi localization of carbohydrate sulfotransferases is a determinant of L-selectin ligand biosynthesisHeparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectinsIdentification of podocalyxin-like protein as a high endothelial venule ligand for L-selectin: parallels to CD34Heterogeneity of endothelial cells: the specialized phenotype of human high endothelial venules characterized by suppression subtractive hybridizationComplexity and differential expression of carbohydrate epitopes associated with L-selectin recognition of high endothelial venulesHuman endomucin: distribution pattern, expression on high endothelial venules, and decoration with the MECA-79 epitopeBiosynthesis and Functional Significance of Peripheral Node Addressin in Cancer-Associated TLODifferential gene expression profile of human tonsil high endothelial cells: implications for lymphocyte traffickingIdentification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesisLymphocyte-HEV interactions in lymph nodes of a sulfotransferase-deficient mouseModulation of L-selectin ligand expression during an immune response accompanying tumorigenesis in transgenic miceLeukocyte adhesion molecules in animal models of inflammatory bowel diseaseCritical role of endothelial P-selectin glycoprotein ligand 1 in chronic murine ileitis.Induction of PNAd and N-acetylglucosamine 6-O-sulfotransferases 1 and 2 in mouse collagen-induced arthritis.C-type lectins and sialyl Lewis X oligosaccharides. Versatile roles in cell-cell interaction.GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice.Human L-selectin preferentially binds synthetic glycosulfopeptides modeled after endoglycan and containing tyrosine sulfate residues and sialyl Lewis x in core 2 O-glycansModulation of endothelial cell adhesion by hevin, an acidic protein associated with high endothelial venules.Novel anti-carbohydrate antibodies reveal the cooperative function of sulfated N- and O-glycans in lymphocyte homing.Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach.A major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules.Functional contributions of N- and O-glycans to L-selectin ligands in murine and human lymphoid organs.Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response.Lymphotoxin plays a crucial role in the development and function of nasal-associated lymphoid tissue through regulation of chemokines and peripheral node addressin.Detection of a sulfotransferase (HEC-GlcNAc6ST) in high endothelial venules of lymph nodes and in high endothelial venule-like vessels within ectopic lymphoid aggregates: relationship to the MECA-79 epitope.Reconstitution of functional L-selectin ligands on a cultured human endothelial cell line by cotransfection of alpha1-->3 fucosyltransferase VII and newly cloned GlcNAcbeta:6-sulfotransferase cDNA.Preparation of Proper Immunogen by Cloning and Stable Expression of cDNA coding for Human Hematopoietic Stem Cell Marker CD34 in NIH-3T3 Mouse Fibroblast Cell LineTransgenic LacZ under control of Hec-6st regulatory sequences recapitulates endogenous gene expression on high endothelial venules.Endothelial ligands for L-selectin: from lymphocyte recirculation to allograft rejection.L-selectin-mediated leukocyte adhesion in vivo: microvillous distribution determines tethering efficiency, but not rolling velocity.Natural killer cell behavior in lymph nodes revealed by static and real-time imaging.Nepmucin, a novel HEV sialomucin, mediates L-selectin-dependent lymphocyte rolling and promotes lymphocyte adhesion under flowSubcellular localization of L-selectin ligand in the endometrium implies a novel function for pinopodes in endometrial receptivity.Sialomucin CD34 is the major L-selectin ligand in human tonsil high endothelial venules.P-selectin must extend a sufficient length from the plasma membrane to mediate rolling of neutrophilsP-selectin glycoprotein ligand 1 is a ligand for L-selectin on neutrophils, monocytes, and CD34+ hematopoietic progenitor cellsSialylated, fucosylated ligands for L-selectin expressed on leukocytes mediate tethering and rolling adhesions in physiologic flow conditions.Impact of fever-range thermal stress on lymphocyte-endothelial adhesion and lymphocyte trafficking.
P2860
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P2860
Sulfation-dependent recognition of high endothelial venules (HEV)-ligands by L-selectin and MECA 79, and adhesion-blocking monoclonal antibody
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
Sulfation-dependent recognitio ...... n-blocking monoclonal antibody
@ast
Sulfation-dependent recognitio ...... n-blocking monoclonal antibody
@en
type
label
Sulfation-dependent recognitio ...... n-blocking monoclonal antibody
@ast
Sulfation-dependent recognitio ...... n-blocking monoclonal antibody
@en
prefLabel
Sulfation-dependent recognitio ...... n-blocking monoclonal antibody
@ast
Sulfation-dependent recognitio ...... n-blocking monoclonal antibody
@en
P2093
P2860
P356
P1476
Sulfation-dependent recognitio ...... n-blocking monoclonal antibody
@en
P2093
E C Butcher
S Hemmerich
P2860
P304
P356
10.1084/JEM.180.6.2219
P407
P577
1994-12-01T00:00:00Z