The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB. - Wikidata - awgldk - TriplyDB

The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB.

The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB.

http://www.wikidata.org/entity/Q36366520

about

Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA Cytotoxic epipolythiodioxopiperazine alkaloids from filamentous fungi of the Bionectriaceae Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis GliZ, a transcriptional regulator of gliotoxin biosynthesis, contributes to Aspergillus fumigatus virulence Aspergillus fumigatus: principles of pathogenesis and host defense Nuclear factor-kappaB activity is down-regulated in nasal polyps from aspirin-sensitive asthmatics Phytotoxic secondary metabolites and peptides produced by plant pathogenic Dothideomycete fungi Quantification of mucosal leucocyte endothelial cell interaction by in vivo fluorescence microscopy in experimental colitis in mice The ubiquitin-proteasome pathway and proteasome inhibitors The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice Aspergillus fumigatus and aspergillosis Current status of novel antifibrotic therapies in patients with chronic liver disease Pseudomonas aeruginosa induces type-III-secretion-mediated apoptosis of macrophages and epithelial cells.Selective inactivation of glutaredoxin by sporidesmin and other epidithiopiperazinediones Detection of gliotoxin in experimental and human aspergillosis Healthy human T-Cell Responses to Aspergillus fumigatus antigens.Diverse agents act at multiple levels to inhibit the Rel/NF-kappaB signal transduction pathway.Vascular injury involves the overoxidation of peroxiredoxin type II and is recovered by the peroxiredoxin activity mimetic that induces reendothelialization.Putative virulence factors of Aspergillus fumigatus.Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites.Redox sensitive epidithiodioxopiperazines in biological mechanisms of toxicity.Natural products as targeted modulators of the nuclear factor-kappaB pathway.The mycotoxins citrinin, gliotoxin, and patulin affect interferon-gamma rather than interleukin-4 production in human blood cells.Inhibiting NF-κB activation by small molecules as a therapeutic strategy.An antimicrobial diketopiperazine alkaloid and co-metabolites from an endophytic strain of Gliocladium isolated from Strychnos cf. toxifera.Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids Antifungal and antihepatotoxic effects of sepia ink extract against oxidative stress as a risk factor of invasive pulmonary aspergillosis in neutropenic mice RsmA regulates Aspergillus fumigatus gliotoxin cluster metabolites including cyclo(L-Phe-L-Ser), a potential new diagnostic marker for invasive aspergillosis.What do we know about the role of gliotoxin in the pathobiology of Aspergillus fumigatus?Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humans Gβ-like CpcB plays a crucial role for growth and development of Aspergillus nidulans and Aspergillus fumigatus Tumour necrosis factor-α regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-κB and AP-1.A novel C2H2 transcription factor that regulates gliA expression interdependently with GliZ in Aspergillus fumigatus.Flice inhibitory protein is associated with the survival of neonatal neutrophils Nuclear factor-kappa B inhibitors as potential novel anti-inflammatory agents for the treatment of immune glomerulonephritis The ubiquitin-proteasome system as a prospective molecular target for cancer treatment and prevention.Export of hepatitis B virus RNA on a Rev-like pathway: inhibition by the regenerating liver inhibitory factor IkappaB alpha.Polarized response of endothelial cells to invasion by Aspergillus fumigatus.Gliotoxin is a virulence factor of Aspergillus fumigatus: gliP deletion attenuates virulence in mice immunosuppressed with hydrocortisone.The immune response to fungal infections.

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P2860

The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB.

http://www.wikidata.org/entity/Q36366520

description

1996 nî lūn-bûn

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1996年の論文

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年學術文章

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1996年學術文章

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1996年學術文章

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name

The immunosuppressive fungal m ...... ranscription factor NF-kappaB.

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The immunosuppressive fungal m ...... ranscription factor NF-kappaB.

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type

label

The immunosuppressive fungal m ...... ranscription factor NF-kappaB.

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The immunosuppressive fungal m ...... ranscription factor NF-kappaB.

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The immunosuppressive fungal m ...... ranscription factor NF-kappaB.

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The immunosuppressive fungal m ...... ranscription factor NF-kappaB.

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Journal of Experimental Medicine

P1476

The immunosuppressive fungal m ...... ranscription factor NF-kappaB.

@en

P2093

A Mühlbacher

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A P Czernilofsky

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B Krauss

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C Myers

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E B Traenckner

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H L Pahl

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K Schulze-Osthoff

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M Vogt

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P A Baeuerle

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P Warring

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P2860

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B

Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element

The RxxRxRxxC motif conserved in all Rel/kappa B proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes

Structural relationship of epipolythiodioxopiperazines and their immunomodulating activity

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

P304

1829-1840

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scholarly article

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10.1084/JEM.183.4.1829

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4

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183

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1996-04-01T00:00:00Z

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8666939

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P932

2192527

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