Differential association of protein tyrosine kinases with the T cell receptor is linked to the induction of anergy and its prevention by B7 family-mediated costimulation.
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FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cellsFYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cellsMolecular mechanisms for adaptive tolerance and other T cell anergy modelsDefective T cell receptor-mediated signal transduction in memory CD4 T lymphocytes exposed to superantigen or anti-T cell receptor antibodiesThe involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activationGrb2 forms an inducible protein complex with CD28 through a Src homology 3 domain-proline interactionGenetic evidence of a role for Lck in T-cell receptor function independent or downstream of ZAP-70/Syk protein tyrosine kinases.Simian immunodeficiency virus Nef protein delays the progression of CD4+ T cells through G1/S phase of the cell cycle.T-cell tolerance and autoimmune diabetes.Intravenous ascorbic acid to prevent and treat cancer-associated sepsis?IL-10-producing T cells suppress immune responses in anergic tuberculosis patients.Glucocorticoids attenuate T cell receptor signaling.Impaired plasma membrane targeting of Grb2-murine son of sevenless (mSOS) complex and differential activation of the Fyn-T cell receptor (TCR)-zeta-Cbl pathway mediate T cell hyporesponsiveness in autoimmune nonobese diabetic mice.Alloantigen-induced unresponsiveness in cord blood T lymphocytes is associated with defective activation of Ras.Cyclin-dependent kinases: molecular switches controlling anergy and potential therapeutic targets for tolerance.T-cell receptor antagonists induce Vav phosphorylation by selective activation of Fyn kinase.Molecular mechanisms of T-cell tolerance.Differential T-cell antigen receptor signaling mediated by the Src family kinases Lck and Fyn.Gene transfer of the Co-stimulatory molecules B7-1 and B7-2 enhances the immunogenicity of human renal cell carcinoma to a different extent.The role of B7-1/B7-2:CD28/CLTA-4 pathways in the prevention of anergy, induction of productive immunity and down-regulation of the immune response.Defective dendritic cell maturation in a child with nucleotide excision repair deficiency and CD4 lymphopenia.Cellular prion protein promotes glucose uptake through the Fyn-HIF-2α-Glut1 pathway to support colorectal cancer cell survival.Apoptosis as a mechanism of peripheral blood mononuclear cell death after measles and varicella-zoster virus infections in children.T cell activation deficiency associated with an aberrant pattern of protein tyrosine phosphorylation after CD3 perturbation in Down's syndrome.CD28 affects the earliest signaling events generated by TCR engagement.The effect of specific immunotherapy on the expression of costimulatory molecules in late phase reaction of the skin in allergic patients.Distinctly different sensitivity in the induction and reversal of anergy of Th1 and Th2 cells.
P2860
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P2860
Differential association of protein tyrosine kinases with the T cell receptor is linked to the induction of anergy and its prevention by B7 family-mediated costimulation.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Differential association of pr ...... family-mediated costimulation.
@ast
Differential association of pr ...... family-mediated costimulation.
@en
type
label
Differential association of pr ...... family-mediated costimulation.
@ast
Differential association of pr ...... family-mediated costimulation.
@en
prefLabel
Differential association of pr ...... family-mediated costimulation.
@ast
Differential association of pr ...... family-mediated costimulation.
@en
P2093
P2860
P356
P1476
Differential association of pr ...... family-mediated costimulation.
@en
P2093
D L Barber
G J Freeman
J G Gribben
L M Nadler
V A Boussiotis
P2860
P304
P356
10.1084/JEM.184.2.365
P407
P577
1996-08-01T00:00:00Z