A single T cell receptor recognizes structurally distinct MHC/peptide complexes with high specificity.
about
Structural Comparison of Allogeneic and Syngeneic T Cell Receptor–Peptide-Major Histocompatibility Complex ComplexesThe three-dimensional structure of a T-cell antigen receptor V alpha V beta heterodimer reveals a novel arrangement of the V beta domain.Co-stimulatory pathways in lymphocyte regulation: the immunoglobulin superfamilyThe peptide-specific alloreactive human T cell repertoire varies largely between individuals and is not extended in HLA-A*0205--anti-HLA-A*0201 pairings.A translatable molecular approach to determining CD8 T-cell epitopes in TMEV infectionPrevalent class I-restricted T-cell response to the Theiler's virus epitope Db:VP2121-130 in the absence of endogenous CD4 help, tumor necrosis factor alpha, gamma interferon, perforin, or costimulation through CD28.Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization.Molecular interactions between extracellular components of the T-cell receptor signaling complex.Dependence of lymphopenia-induced T cell proliferation on the abundance of peptide/ MHC epitopes and strength of their interaction with T cell receptors.Diversity-oriented approaches for interrogating T-cell receptor repertoire, ligand recognition, and functionDesign of T-cell receptor libraries with diverse binding properties to examine adoptive T-cell responses.Evolving concepts of specificity in immune reactionsA novel T cell receptor single-chain signaling complex mediates antigen-specific T cell activity and tumor controlT cell receptor interactions with class I heavy-chain influence T cell selection.Opposite effects of endogenous peptide-MHC class I on T cell activity in the presence and absence of CD8.Identities of P2 and P3 Residues of H-2Kb-Bound Peptides Determine Mouse Ly49C Recognition.H2-DMalpha(-/-) mice show the importance of major histocompatibility complex-bound peptide in cardiac allograft rejectionDifferences in the level of expression of class I major histocompatibility complex proteins on thymic epithelial and dendritic cells influence the decision of immature thymocytes between positive and negative selection.Negative selection imparts peptide specificity to the mature T cell repertoire.Dual HLA class I and class II restricted recognition of alloreactive T lymphocytes mediated by a single T cell receptor complex.Role of 2CT cell receptor residues in the binding of self- and allo-major histocompatibility complexesA naturally processed mitochondrial self-peptide in complex with thymic MHC molecules functions as a selecting ligand for a viral-specific T cell receptor.Cross-presentation of disialoganglioside GD3 to natural killer T cells.Analysis of the expression of peptide-major histocompatibility complexes using high affinity soluble divalent T cell receptorsRole of T cell receptor affinity in the efficacy and specificity of adoptive T cell therapies.Crossreactive recognition of viral, self, and bacterial peptide ligands by human class I-restricted cytotoxic T lymphocyte clonotypes: implications for molecular mimicry in autoimmune diseaseMHC restriction and allogeneic immune responses.Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes.Long-term persistence of CD4(+) but rapid disappearance of CD8(+) T cells expressing an MHC class I-restricted TCR of nanomolar affinityCellular uptake followed by class I MHC presentation of some exogenous peptides contributes to T cell stimulatory capacity.Integrin-mediated interactions influence the tissue specificity of CD8+ cytolytic T lymphocytes.Identification of a cross-reactive self ligand in virus-mediated autoimmunity.A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity.Probing the activation requirements for naive CD8+ T cells with Drosophila cell transfectants as antigen presenting cells.
P2860
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P2860
A single T cell receptor recognizes structurally distinct MHC/peptide complexes with high specificity.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
A single T cell receptor recog ...... mplexes with high specificity.
@ast
A single T cell receptor recog ...... mplexes with high specificity.
@en
type
label
A single T cell receptor recog ...... mplexes with high specificity.
@ast
A single T cell receptor recog ...... mplexes with high specificity.
@en
prefLabel
A single T cell receptor recog ...... mplexes with high specificity.
@ast
A single T cell receptor recog ...... mplexes with high specificity.
@en
P2093
P2860
P356
P1476
A single T cell receptor recog ...... mplexes with high specificity.
@en
P2093
P2860
P304
P356
10.1084/JEM.184.3.1017
P407
P577
1996-09-01T00:00:00Z