Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules.
about
Small molecules that enhance the catalytic efficiency of HLA-DMAn MHC class II restriction bias in CD4 T cell responses toward I-A is altered to I-E in DM-deficient miceCrystal Structure of the HLA-DM–HLA-DR1 Complex Defines Mechanisms for Rapid Peptide SelectionAchieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expressionThe impact of the non-classical MHC proteins HLA-DM and HLA-DO on loading of MHC class II moleculesHLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptidePhagocytic antigen processing and effects of microbial products on antigen processing and T-cell responses.Peptide exchange in MHC molecules.On the perils of poor editing: regulation of peptide loading by HLA-DQ and H2-A molecules associated with celiac disease and type 1 diabetes.Phagocytic processing of antigens for presentation by class II major histocompatibility complex molecules.Binding interactions between peptides and proteins of the class II major histocompatibility complex.The mechanism of HLA-DM induced peptide exchange in the MHC class II antigen presentation pathwayIn the absence of the invariant chain, HLA-DR molecules display a distinct array of peptides which is influenced by the presence or absence of HLA-DMEmpty class II major histocompatibility complex created by peptide photolysis establishes the role of DM in peptide association.The impact of DM on MHC class II-restricted antigen presentation can be altered by manipulation of MHC-peptide kinetic stabilityThe relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes.DM determines the cryptic and immunodominant fate of T cell epitopes.How many thymocytes audition for selection?Functionality of major histocompatibility complex class II molecules in mice doubly deficient for invariant chain and H-2M complexesImmunodominance in CD4 T-cell responses: implications for immune responses to influenza virus and for vaccine design.The control of the specificity of CD4 T cell responses: thresholds, breakpoints, and ceilingsIntestinal epithelial cells use two distinct pathways for HLA class II antigen processing.Endocytic recycling is required for the presentation of an exogenous peptide via MHC class II molecules.HLA-DM can partially replace the invariant chain for HLA-DR transport and surface expression in transfected endocrine epithelial cells.A role for HLA-DO as a co-chaperone of HLA-DM in peptide loading of MHC class II molecules.Determinants of the peptide-induced conformational change in the human class II major histocompatibility complex protein HLA-DR1.Distinct intracellular compartments involved in invariant chain degradation and antigenic peptide loading of major histocompatibility complex (MHC) class II moleculesImmunodominance of CD4 T cells to foreign antigens is peptide intrinsic and independent of molecular context: implications for vaccine design.Effects of prostaglandin F2alpha and progesterone on the ability of bovine luteal cells to stimulate T lymphocyte proliferation.Secondary structure composition and pH-dependent conformational changes of soluble recombinant HLA-DM.The Ii41 isoform of invariant chain mediates both positive and negative selection events in T-cell receptor transgenic mice.
P2860
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P2860
Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Invariant chain and DM edit se ...... plex (MHC) class II molecules.
@ast
Invariant chain and DM edit se ...... plex (MHC) class II molecules.
@en
type
label
Invariant chain and DM edit se ...... plex (MHC) class II molecules.
@ast
Invariant chain and DM edit se ...... plex (MHC) class II molecules.
@en
prefLabel
Invariant chain and DM edit se ...... plex (MHC) class II molecules.
@ast
Invariant chain and DM edit se ...... plex (MHC) class II molecules.
@en
P2093
P2860
P356
P1476
Invariant chain and DM edit se ...... plex (MHC) class II molecules.
@en
P2093
P2860
P304
P356
10.1084/JEM.184.5.1747
P407
P577
1996-11-01T00:00:00Z