A gene required for class II-restricted antigen presentation maps to the major histocompatibility complex
about
Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epitheliumAllelic variants of the human putative peptide transporter involved in antigen processingA step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cellsAn MHC class II restriction bias in CD4 T cell responses toward I-A is altered to I-E in DM-deficient miceAchieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expressionAltered major histocompatibility complex class II peptide loading in H2-O-deficient miceIntracellular transport and peptide loading of MHC class II molecules: regulation by chaperones and motors.Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DMPulse-chase analysis for studies of MHC class II biosynthesis, maturation, and peptide loading.Binding interactions between peptides and proteins of the class II major histocompatibility complex.Generation of MHC class II-peptide ligands for CD4 T-cell allorecognition of MHC class II molecules.Deficient antigen-presenting cell function in multiple genetic complementation groups of type II bare lymphocyte syndrome.In the absence of the invariant chain, HLA-DR molecules display a distinct array of peptides which is influenced by the presence or absence of HLA-DMThe relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes.Major histocompatibility complex class II-restricted presentation of an internally synthesized antigen displays cell-type variability and segregates from the exogenous class II and endogenous class I presentation pathwaysA mutant human histocompatibility leukocyte antigen DR molecule associated with invariant chain peptides.Coordinate defects in human histocompatibility leukocyte antigen class II expression and antigen presentation in bare lymphocyte syndrome.The requirement for DM in class II-restricted antigen presentation and SDS-stable dimer formation is allele and species dependent.A novel antigen-processing-defective phenotype in major histocompatibility complex class II-positive CIITA transfectants is corrected by interferon-gamma.Genetic evidence for a new type of major histocompatibility complex class II combined immunodeficiency characterized by a dyscoordinate regulation of HLA-D alpha and beta chains.Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules.HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR moleculesNovel mutants define genes required for the expression of human histocompatibility leukocyte antigen DM: evidence for loci on human chromosome 6pDM influences the abundance of major histocompatibility complex class II alleles with low affinity for class II-associated invariant chain peptides via multiple mechanisms.Masking of a cathepsin G cleavage site in vivo contributes to the proteolytic resistance of major histocompatibility complex class II molecules.Mitotic recombination of yeast artificial chromosomes.A T cell-specific enhancer of the human CD40 ligand gene.Class II antigen processing compartments and the function of HLA-DM.Antigen presentation by MHC class II molecules.Genomic MHC haplotyping of mutant cell lines using a novel marker.Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO.Thymus, thymoma, and specific T cells in myasthenia gravis.
P2860
Q24318429-76035708-3DCD-41E8-8F21-03068FB7FE01Q24561683-2C3DBB8E-551C-4391-9A2B-EB75FE4FAD0CQ26747063-57E1FD10-DA48-4E04-856B-C654ED74CF40Q27469164-F7BB8C32-2BC0-49AA-AD5F-CB057A3D19BEQ28273723-F216AF1C-1FEA-4D86-8F8B-D804DBF8259DQ28510157-8AB7F7E3-0A2F-4C13-998E-C71104DBF810Q33815425-AE18B7D9-0E70-4002-BA02-CD365E7A7B81Q34083338-81E3EE56-56EF-4780-95BE-92BB81C82A7FQ34155809-58A86132-D312-4AC3-8460-EC876386B55EQ34540061-5F997D2D-8362-409E-A09B-CBA23696E075Q34893634-7A8FAD0D-8A0D-4A30-B464-B7DE6EB7C911Q35750316-493388EE-E450-4A9F-B563-545E044FBEC1Q36158655-B77F5184-A0DC-45E6-BB0E-D7ADB5F40971Q36266503-30476AC1-C04F-4AA0-9446-4E0765A638E5Q36361976-8DC5A14B-2F4D-4E34-857A-F7A61AC6A644Q36362737-8F9D4FE8-7BD6-4950-AE4F-85DC246B1A35Q36363208-24A736D1-43DD-4C0B-B1D3-CE67ECDD6B02Q36364225-2055BA05-A9D1-4BB5-82E2-44DE4B4B239AQ36365569-E45F310D-25CA-4DA0-8027-E95944F62BFDQ36365805-6B2D1C44-73AC-429A-B11E-303F4D7E925DQ36367514-5279A8AC-F539-4E1D-BF9C-4EEC69547244Q36377428-5065FAE6-C736-44A8-904B-43552194358CQ36380786-4B4F62DB-0CE5-49AE-A2F9-3B641215224DQ39712353-8C1EE318-73D2-48F7-AF16-1D93A34FCF3DQ39724282-AA75734D-19A4-4026-8BE8-509DEDBF6C24Q40422724-67177E1B-341C-4B5E-B4F1-D0B0E3321A5AQ40761786-D3479006-DAE5-4294-BC71-527CA541FDB7Q41091901-6B44924E-F7D8-49CA-9FD9-E4B3D42A7996Q41359341-E779863E-872A-45BD-914C-5A5B7FCA56B9Q41521522-14A8EAD7-CCEC-4D17-A309-398A29E63BF6Q42944165-47C441A0-C4FF-472E-A633-7B52BE9B19DCQ47826755-84781A93-33DC-4CED-A470-0E30DFB65DDF
P2860
A gene required for class II-restricted antigen presentation maps to the major histocompatibility complex
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
A gene required for class II-r ...... jor histocompatibility complex
@ast
A gene required for class II-r ...... jor histocompatibility complex
@en
type
label
A gene required for class II-r ...... jor histocompatibility complex
@ast
A gene required for class II-r ...... jor histocompatibility complex
@en
prefLabel
A gene required for class II-r ...... jor histocompatibility complex
@ast
A gene required for class II-r ...... jor histocompatibility complex
@en
P2093
P2860
P356
P1476
A gene required for class II-r ...... jor histocompatibility complex
@en
P2093
P2860
P304
P356
10.1084/JEM.174.6.1607
P407
P577
1991-12-01T00:00:00Z