Growth inhibition and apoptosis due to restoration of E2A activity in T cell acute lymphoblastic leukemia cells.
about
Promotion of cell cycle progression by basic helix-loop-helix E2AmSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factorHelix-loop-helix proteins: regulators of transcription in eucaryotic organismsDifferential gene expression in human hepatocellular carcinoma Hep3B cells induced by apoptosis-related gene BNIPL-2The TAL1/SCL transcription factor regulates cell cycle progression and proliferation in differentiating murine bone marrow monocyte precursorsRegulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade.E proteins and the regulation of early lymphocyte developmentThe role of E2A-PBX1 in leukemogenesis.E2A-HLF usurps control of evolutionarily conserved survival pathways.The function of E- and Id proteins in lymphocyte development.The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 geneGenomic loss of the putative tumor suppressor gene E2A in human lymphoma.Helix-loop-helix proteins and lymphocyte development.E2A promotes the survival of precursor and mature B lymphocytes.Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytes.Balance between Id and E proteins regulates myeloid-versus-lymphoid lineage decisions.Increased level of E protein activity during invariant NKT development promotes differentiation of invariant NKT2 and invariant NKT17 subsets.Repression of TCF3/E2A contributes to Hodgkin lymphomagenesis.Differential involvement of E2A-corepressor interactions in distinct leukemogenic pathways.E2A predicts prognosis of colorectal cancer patients and regulates cancer cell growth by targeting miR-320aNew insights into transcriptional and leukemogenic mechanisms of AML1-ETO and E2A fusion proteins.Enforced expression of E47 has differential effects on Lmo2-induced T-cell leukemias.Targeting the bHLH transcriptional networks by mutated E proteins in experimental glioma.E2A proteins enforce a proliferation checkpoint in developing thymocytesMassive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice.Identification of cyclin D3 as a direct target of E2A using DamID.Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphomaEarly thymocyte development is regulated by modulation of E2A protein activity.Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1.E2A/HEB and Id3 proteins control the sensitivity to glucocorticoid-induced apoptosis in thymocytes by regulating the SRG3 expression.TAL1/SCL is downregulated upon histone deacetylase inhibition in T-cell acute lymphoblastic leukemia cells
P2860
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P2860
Growth inhibition and apoptosis due to restoration of E2A activity in T cell acute lymphoblastic leukemia cells.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Growth inhibition and apoptosi ...... lymphoblastic leukemia cells.
@ast
Growth inhibition and apoptosi ...... lymphoblastic leukemia cells.
@en
type
label
Growth inhibition and apoptosi ...... lymphoblastic leukemia cells.
@ast
Growth inhibition and apoptosi ...... lymphoblastic leukemia cells.
@en
prefLabel
Growth inhibition and apoptosi ...... lymphoblastic leukemia cells.
@ast
Growth inhibition and apoptosi ...... lymphoblastic leukemia cells.
@en
P2093
P2860
P356
P1476
Growth inhibition and apoptosi ...... lymphoblastic leukemia cells.
@en
P2093
P2860
P304
P356
10.1084/JEM.189.3.501
P407
P577
1999-02-01T00:00:00Z