Inactivation of MARK4, an AMP-activated protein kinase (AMPK)-related kinase, leads to insulin hypersensitivity and resistance to diet-induced obesity
about
Regulation of blood-testis barrier by actin binding proteins and protein kinasesEvidence of cancer-promoting roles for AMPK and related kinasesMARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanismProtein partners of KCTD proteins provide insights about their functional roles in cell differentiation and vertebrate development.Salt-inducible Kinase 3 Signaling Is Important for the Gluconeogenic Programs in Mouse Hepatocytes.Mark4 promotes oxidative stress and inflammation via binding to PPARγ and activating NF-κB pathway in mice adipocytes.SAD-A potentiates glucose-stimulated insulin secretion as a mediator of glucagon-like peptide 1 response in pancreatic β cells.SAD-A kinase controls islet β-cell size and function as a mediator of mTORC1 signaling.ssc-miR-7134-3p regulates fat accumulation in castrated male pigs by targeting MARK4 gene.New perspectives on the development of antiobesity drugs.The CLASP2 Protein Interaction Network in Adipocytes Links CLIP2 to AGAP3, CLASP2 to G2L1, MARK2, and SOGA1, and Identifies SOGA1 as a Microtubule-Associated Protein.Regulation of Cell Polarity by PAR-1/MARK Kinase.Microtubule affinity-regulating kinases are potential druggable targets for Alzheimer's disease.Partitioning-Defective 1a/b Depletion Impairs Glomerular and Proximal Tubule Development.SAD-A and AMPK kinases: the "yin and yang" regulators of mTORC1 signaling in pancreatic β cells.Mark4 promotes adipogenesis and triggers apoptosis in 3T3-L1 adipocytes by activating JNK1 and inhibiting p38MAPK pathways.Tau phosphorylation at Alzheimer's disease-related Ser356 contributes to tau stabilization when PAR-1/MARK activity is elevated.Human Protein Kinases and Obesity.Evaluation of human microtubule affinity-regulating kinase 4 inhibitors: fluorescence binding studies, enzyme, and cell assays.Human microtubule affinity-regulating kinase 4 is stable at extremes of pH.
P2860
Q26775517-8A41BD9E-2EFE-4176-B580-43885862968EQ28083964-29BDBA9F-D527-434B-94DD-3DCA83C736FCQ33861382-9CFA8D96-88C7-4694-9D20-F347050BED25Q34339689-A6DC2176-7A6E-4001-8726-4AC044E67C36Q35859504-D7222B75-2A83-4827-9453-7892822DD5C3Q36616948-EF212AAD-B1D4-4A9D-9520-01AE1AC1591DQ36978302-E473A7AB-C991-4531-8DFD-DCA2784469E5Q37117860-655C8B23-D173-4038-BBBE-1E9788CA64E6Q37675892-7D6FCD44-703A-4AE9-A4FF-FE59E1440F00Q38397340-DA6A8E58-9E2E-4AA3-9136-87278A7896C2Q38760699-9B304C64-570D-408F-986A-A24747E55F72Q39150579-A0C1E0E2-2723-4718-9355-572FF2BA1228Q39387270-78CDDA87-0AA8-407A-BCAE-BEC137B71579Q39761428-6186507D-0C6A-4C18-9027-6DBABBD07949Q41878459-F02924F6-E7DA-4106-8A5C-29D2BD372D55Q42800188-73EB6447-E724-41EE-9123-FE5558FCB841Q43264384-B1CC3828-D3B4-4E2A-AB78-81FF2A2FED24Q46355687-B40EE644-EFB2-4E7D-8B1A-12187F41F638Q48248331-A73D4933-56E4-4CBB-9601-13B2CF8A28E3Q53793410-D847EEA4-75F8-44F0-B26E-5038404B99BA
P2860
Inactivation of MARK4, an AMP-activated protein kinase (AMPK)-related kinase, leads to insulin hypersensitivity and resistance to diet-induced obesity
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Inactivation of MARK4, an AMP- ...... stance to diet-induced obesity
@ast
Inactivation of MARK4, an AMP- ...... stance to diet-induced obesity
@en
type
label
Inactivation of MARK4, an AMP- ...... stance to diet-induced obesity
@ast
Inactivation of MARK4, an AMP- ...... stance to diet-induced obesity
@en
prefLabel
Inactivation of MARK4, an AMP- ...... stance to diet-induced obesity
@ast
Inactivation of MARK4, an AMP- ...... stance to diet-induced obesity
@en
P2093
P2860
P356
P1476
Inactivation of MARK4, an AMP- ...... stance to diet-induced obesity
@en
P2093
P2860
P304
38305-38315
P356
10.1074/JBC.M112.388934
P407
P577
2012-09-19T00:00:00Z