Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells. - Wikidata - awgldk - TriplyDB

Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells.

Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells.

http://www.wikidata.org/entity/Q36369031

about

Interleukin-15 biology and its therapeutic implications in cancer IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease-associated inflammation and lymphomagenesis Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes Regulating the immune system via IL-15 transpresentation Natural killer cell regulation by microRNAs in health and disease Animal models to study gluten sensitivity Targeting the binding interface on a shared receptor subunit of a cytokine family enables the inhibition of multiple member cytokines with selectable target spectrum.Constitutive type I interferon modulates homeostatic balance through tonic signaling Role of the inositol polyphosphate-4-phosphatase type II Inpp4b in the generation of ovarian teratomas Tumor growth decreases NK and B cells as well as common lymphoid progenitor.A novel mouse model for the aggressive variant of NK cell and T cell large granular lymphocyte leukemia.Cytokines as Adjuvants for Vaccine and Cellular Therapies for Cancer.NK and NKT cell-independent contribution of interleukin-15 to innate protection against mucosal viral infection Diacylglycerol Kinase ζ Limits Cytokine-dependent Expansion of CD8+ T Cells with Broad Antitumor Capacity.IL-15.IL-15Rα complex shedding following trans-presentation is essential for the survival of IL-15 responding NK and T cells IL-7 and IL-21 are superior to IL-2 and IL-15 in promoting human T cell-mediated rejection of systemic lymphoma in immunodeficient mice.IL-15 plays a major role in the persistence of Tax-specific CD8 cells in HAM/TSP patients.{gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells.In vivo role of Flt3 ligand and dendritic cells in NK cell homeostasis NKp46 identifies an NKT cell subset susceptible to leukemic transformation in mouse and human.Characterization of human T lymphocytes engineered to express interleukin-15 and herpes simplex virus-thymidine kinase Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia.Nonalcoholic steatosis and steatohepatitis IV. Nonalcoholic fatty liver disease abnormalities in macrophage function and cytokines.Liver gene transfer of interkeukin-15 constructs that become part of circulating high density lipoproteins for immunotherapy Molecular mechanisms influencing NK cell development: implications for NK cell malignancies.Primary human T lymphocytes engineered with a codon-optimized IL-15 gene resist cytokine withdrawal-induced apoptosis and persist long-term in the absence of exogenous cytokine.CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSP Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity.Perturbed thymopoiesis in vitro in the absence of suppressor of cytokine signalling 1 and 3.Development of an IL-15-autocrine CD8 T-cell leukemia in IL-15-transgenic mice requires the cis expression of IL-15Rα.Dendritic cell-derived interleukin-15 is crucial for therapeutic cancer vaccine potency.IL-15R alpha expression on CD8+ T cells is dispensable for T cell memory Mechanistic model of natural killer cell proliferative response to IL-15 receptor stimulation Evolving insights in the pathogenesis and therapy of cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome)Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations.Role of common-gamma chain cytokines in NK cell development and function: perspectives for immunotherapy.An antagonist mutant IL-15/Fc promotes transplant tolerance.Overexpression of IL-15 promotes tumor destruction via NK1.1+ cells in a spontaneous breast cancer model.

P2860

Q24595605-40F070AA-F9F6-4EF0-A432-F8B88213DCC5 Q24604346-3D551622-ECA4-482B-B289-CB7DDC688F4B Q24616204-5D7F3FB7-CAEF-4236-93D5-654D33C74CFE Q24644114-A1EFDD5E-9A0B-4A34-9736-0B62A27735AD Q26825247-53C329CE-1200-4DE3-A2FC-782DA740FC4D Q26849448-751F431F-3304-4506-9CE3-09B926D38876 Q26859130-5EE0780B-5B89-4C32-BD66-739F6EAFB62F Q27312407-E90E2D3E-3D8B-4EAF-97E7-616CFF489E89 Q28260631-85928DC5-B1FD-465E-8675-AB2C194161E1 Q28587137-7B921CD3-D816-4BC9-9196-DAA735B76198 Q33368635-3F24E035-C260-4E74-B3A4-D6B777AF9BA3 Q33624229-58680604-0540-48F6-AE35-E57909D3E5F6 Q33680566-498C0591-499C-42EB-9A45-99A921C267D3 Q33707533-DBA7C974-1F6F-4778-8A01-AD7DB536F167 Q33715829-1E1CD6F5-0C13-4DA1-8121-0881458E397F Q33767707-6AC69FE3-2DA8-4827-AA84-60E8350B27D0 Q33839836-B3737A0B-3B9F-475A-B3D0-7BEBBD75E88C Q33952031-02750C6B-A24A-4D3D-A290-C3ACE39E5956 Q34055649-86D00D3C-A566-4408-A0ED-7A1E476652C5 Q34076517-2FC9769E-F8E8-4ABC-960B-DD36825D6987 Q34167778-703503F8-7B66-4F6D-A2C4-238A89134E93 Q34338927-BC91C543-B9F4-4614-9B20-EF09FB92743F Q34369832-856164BD-2CE1-4DA4-AAF6-D7826E9E90EE Q34396332-A690F00B-DB00-41CF-9A5C-8D042BEC5AE4 Q34467338-529B1C2B-4051-49EA-B789-6834F1E26E68 Q34533728-449DFBB1-975F-407F-AA48-2C0766579199 Q34636731-C611AF4B-6051-4773-BEE1-0F88D17E3801 Q34657676-862B22D1-9830-4E00-B4E6-646F9E52B3C5 Q34667760-4DE4D0BE-56A4-4557-BE92-577714A8CA5A Q34724122-C7D92956-50E0-45FE-9A4D-382CFDCA3E0A Q34920500-FA4CF68F-C964-41C3-8D56-026180735E6E Q34924364-FE95B0ED-DA65-47A6-AF5B-D9F6466ABD99 Q34936507-9BB9F8A9-9CCD-476A-953A-11803ACB51AB Q34960007-FD50C72A-030E-4396-852D-CDFEA51BCE5A Q34998162-AC2C34A5-43F6-4244-8B9E-9303018FDD59 Q35022833-D7ED9B2D-E6A5-46F2-AA13-DD610993C7D4 Q35025549-6A005803-E94A-4617-8FE9-917DD20313CC Q35054508-6B4B1B46-E170-48A7-99EF-B71D68A48EDE Q35087089-8EE14E60-7905-4EC8-8EB4-2EDE2C02B1E1 Q35595605-AF536E87-8DEC-4CAC-9D37-F82463ACD466

P2860

Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells.

http://www.wikidata.org/entity/Q36369031

description

2001 nî lūn-bûn

@nan

2001年の論文

@ja

2001年学术文章

@wuu

2001年学术文章

@zh-cn

2001年学术文章

@zh-hans

2001年学术文章

@zh-my

2001年学术文章

@zh-sg

2001年學術文章

@yue

2001年學術文章

@zh

2001年學術文章

@zh-hant

name

Fatal leukemia in interleukin ...... memory phenotype CD8+ T cells.

@ast

Fatal leukemia in interleukin ...... memory phenotype CD8+ T cells.

@en

type

label

Fatal leukemia in interleukin ...... memory phenotype CD8+ T cells.

@ast

Fatal leukemia in interleukin ...... memory phenotype CD8+ T cells.

@en

prefLabel

Fatal leukemia in interleukin ...... memory phenotype CD8+ T cells.

@ast

Fatal leukemia in interleukin ...... memory phenotype CD8+ T cells.

@en

P1433

Q36369031-F59E0C96-E1CA-4231-95BB-DCC1918F9D22

P1476

Q36369031-040730ED-1D29-4280-8260-B51ADE18FE72

P2093

Q36369031-083B1513-E640-4A40-A295-1281D44B6921

Q36369031-1BAA1368-C8E8-41E1-B8AA-815221626A83

Q36369031-25CA41DA-D8DC-4E35-80D3-1654CE309656

Q36369031-2FACD5A4-FC86-47A3-972F-2BA90BACC88F

Q36369031-3384B39E-1154-4E17-8D05-D9926F9506F3

Q36369031-343A0B0E-D2AF-4AF5-AD19-8CC0A72C20A1

Q36369031-871292E8-581E-48C5-B328-0EF97C8409BB

Q36369031-95A92152-0622-4E4C-B456-E5ACD420DA97

Q36369031-FC4937EB-3BF3-4BE5-A892-9B5CCCA1E11B

P2860

Q36369031-0504F627-061F-4090-8948-88815350CA4A

Q36369031-084C379B-C0FA-4650-BB02-FD92F72A56F4

Q36369031-17152F70-2B3F-4E7E-9914-84A4E1CF3217

Q36369031-1D9AEF59-156D-428F-AF4D-B539159737D9

Q36369031-1F494AB7-E15F-4B5B-8008-7FA1AF241ACB

Q36369031-283E6D14-96E4-46C9-B690-EE64C6CC591B

Q36369031-2EFF0881-231F-4CD3-8FA9-FC6694A8C89A

Q36369031-326C7693-AA76-4104-84D2-B3B0681BA42E

Q36369031-3752219E-3711-4EA4-942B-2403B7BB75A9

Q36369031-3B041E5E-6C91-47E4-A548-23F6398E9DC7

P304

Q36369031-70E341FD-74CB-479D-ACF4-F64AB2567D3A

P31

Q36369031-7E8F6C5A-C73D-4E4B-A0D9-AB9DF57B6025

P356

Q36369031-835B8D1D-1F9B-4E24-8CA7-DEC353DDF37F

P407

Q36369031-1463ACD0-5BBA-4FDF-9A4F-5D55150DE315

P433

Q36369031-99238E89-DCA9-4399-8600-EADE03CF0813

P478

Q36369031-D2A5D510-500C-4AA7-891A-42F8E5E8704E

P50

Q36369031-CE0BBD35-8174-4A71-8EC5-1F3261145094

P577

Q36369031-5A7B95D9-B664-41FC-B466-D8C2A0B8941B

P5875

Q36369031-0812C6A6-99E2-4CDE-AEBA-CD1BACE52389

P698

Q36369031-3F95D2E4-CA1C-4414-9734-E8F4CB6FBCCA

P921

Q36369031-524640C0-5775-47CF-9C7B-49C64562C7CB

Q36369031-52de8b6c-d089-4e1c-9bb4-4f35531f81a0

P932

Q36369031-11F6B225-BA19-4AF9-9E55-77DE6745234C

P356

P1433

Journal of Experimental Medicine

P1476

Fatal leukemia in interleukin ...... memory phenotype CD8+ T cells

@en

P2093

A G Freud

http://www.w3.org/2001/XMLSchema#string

A Ponnappan

http://www.w3.org/2001/XMLSchema#string

J B VanDeusen

http://www.w3.org/2001/XMLSchema#string

J Durbin

http://www.w3.org/2001/XMLSchema#string

K Suzuki

http://www.w3.org/2001/XMLSchema#string

M A Caligiuri

http://www.w3.org/2001/XMLSchema#string

M A Cooper

http://www.w3.org/2001/XMLSchema#string

M L Robinson

http://www.w3.org/2001/XMLSchema#string

S M Florea

http://www.w3.org/2001/XMLSchema#string

P2860

A proinflammatory cytokine inhibits p53 tumor suppressor activity

Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor

Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor

Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15

Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides

Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo

Interleukin-1 polymorphisms associated with increased risk of gastric cancer

The 5' untranslated region, signal peptide, and the coding sequence of the carboxyl terminus of IL-15 participate in its multifaceted translational control

Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment

P304

219-231

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1084/JEM.193.2.219

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

193

http://www.w3.org/2001/XMLSchema#string

P50

Todd A Fehniger

P577

2001-01-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

236245588

http://www.w3.org/2001/XMLSchema#string

P698

11208862

http://www.w3.org/2001/XMLSchema#string

P921

P932

2193336

http://www.w3.org/2001/XMLSchema#string