Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations. - Wikidata - awgldk - TriplyDB

Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations.

Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations.

http://www.wikidata.org/entity/Q35025549

about

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing 3-dimensional imaging modalities for phenotyping genetically engineered mice Structural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone Methyltransferases A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias Disordered epigenetic regulation in MLL-related leukemia.Genetics and epigenetics of the skin meet deep sequence.Echinomycin protects mice against relapsed acute myeloid leukemia without adverse effect on hematopoietic stem cells Leukaemogenesis: more than mutant genes Rbm15-Mkl1 interacts with the Setd1b histone H3-Lys4 methyltransferase via a SPOC domain that is required for cytokine-independent proliferation.Two decades of leukemia oncoprotein epistasis: the MLL1 paradigm for epigenetic deregulation in leukemia.Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia Identification of functional cooperative mutations of SETD2 in human acute leukemia.Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells.MLL fusions: pathways to leukemia Long-term disease-free survivors with cytogenetically normal acute myeloid leukemia and MLL partial tandem duplication: a Cancer and Leukemia Group B study.Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond The pathogenesis of mixed-lineage leukemia.Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells DNA hypermethylation and epigenetic silencing of the tumor suppressor gene, SLC5A8, in acute myeloid leukemia with the MLL partial tandem duplication.The Mll partial tandem duplication: differential, tissue-specific activity in the presence or absence of the wild-type allele Epigenetics in acute myeloid leukemia.Eradicating acute myeloid leukemia in a Mll(PTD/wt):Flt3(ITD/wt) murine model: a path to novel therapeutic approaches for human disease.Translocations in epithelial cancers.Etoposide-initiated MLL rearrangements detected at high frequency in human primitive hematopoietic stem cells with in vitro and in vivo long-term repopulating potential.Novel targeted drug therapies for the treatment of childhood acute leukemia Ordering of mutations in acute myeloid leukemia with partial tandem duplication of MLL (MLL-PTD).Comparative transcriptome analysis reveals a regulatory network of microRNA-29b during mouse early embryonic development.RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.Double-strand breaks and the concept of short- and long-term epigenetic memory.The role of HDACs inhibitors in childhood and adolescence acute leukemias.Transcriptional and epigenetic networks in haematological malignancy.The role of Hox proteins in leukemogenesis: insights into key regulatory events in hematopoiesis.Epigenetic alterations in hematopoietic malignancies.Tipping the lysine methylation balance in disease Context-specific regulation of cancer epigenomes by histone and transcription factor methylation.Mixed lineage leukemia protein in normal and leukemic stem cells.Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis.

P2860

Q24605342-DC09D1E7-82AE-4BA8-8F1F-2EB997CEAF77 Q24653015-6C04BD14-F713-4100-A5B7-578C86AAC9E2 Q26999618-879C47B2-4586-4881-B198-D4D56FDBDC34 Q27679498-01037792-7C8B-4786-B0EA-4EC6003B0A62 Q28298834-CD45443F-D720-49ED-A01F-7E00A3F2307B Q28508217-8177BCD5-1687-4A11-9A2D-F5E558C490A1 Q28594733-55BD5BAA-0F74-413B-9ABE-2F1B82D460D3 Q30422159-B83D13F6-9AC4-4BF0-9F94-6CD535F636C1 Q33904361-B8384EE4-0A88-4A1F-81E7-871E83B33D9A Q34047867-A74FB335-3171-4CDF-94A1-3D2AF5273F63 Q34275371-E367D899-CFEF-4CA1-9EF5-6BC8FED30549 Q34395567-5504A165-656F-4329-8979-C19291B26EA9 Q35018755-9B3EEB19-7174-44BE-A917-07FD075C7A95 Q35265916-9A115CA4-ABB7-4C1A-AB73-88545B8E6F77 Q35632973-D01B200D-D9F6-42D9-A202-4A0D5148F0DE Q35685082-6792000C-75F0-41E3-A33A-AAA19526B83D Q35788362-CBEA7B06-980F-4DF8-8F28-863946215750 Q35839909-53358179-61A6-4719-A052-9CF0518E08F8 Q35967446-800EA34E-6D80-4863-91D9-C50573B7AAAA Q36052947-F7394ED0-0E5C-420F-96A5-B82F3216D5F6 Q36141856-B25E2285-3872-4F43-9FC2-E292FD2EF7E7 Q36843784-1B1EB9DE-2AEB-4349-A0A5-D96100E86314 Q36868776-64292F4D-B08F-4071-B44A-53118D97C5A6 Q37240566-90E62663-44ED-45D5-8208-4ECBE80207BC Q37349410-BE80C102-D3B7-4317-95F8-AF1B8D01F757 Q37363960-2D18FDF7-8C71-4437-850B-4F654794BFE1 Q37463163-D5C6F657-8077-4BE7-A5A9-4063B5CC220C Q37477482-07E18DF8-7EA1-4A47-AA52-7FA71BD36D10 Q37559783-D592E1A1-9868-443B-B991-C2875D20CB76 Q37619825-B41BD417-92FF-4345-AD48-61E92EE70D80 Q37621929-0531AABD-E83D-44BE-8B81-BFC98C5BD09C Q37822707-B954E996-B934-436F-9E68-20C5C1477068 Q37841146-432B9B13-DFE8-493B-8782-0ABF25485713 Q37863271-14DB04EC-0380-4826-BA3F-96C1A6D5E4D4 Q37965801-60BDE5C7-7262-448A-BF4B-5240C8FDF8BB Q38046794-E8553C2A-263F-4B8B-A739-2DE69F37FCC7 Q38061868-2CA53ACA-892A-41C9-AA99-229609A128F1 Q38090433-CA034E58-6619-4843-9B6F-157094FB0173 Q38100107-A3DD2B77-FC7D-474E-9818-6BA603D8C284 Q38161393-53C127C6-2703-4686-8A3B-14ABBA9FD0C2

P2860

Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations.

http://www.wikidata.org/entity/Q35025549

description

2006 nî lūn-bûn

@nan

2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Mll partial tandem duplication ...... ecific epigenetic alterations.

@ast

Mll partial tandem duplication ...... ecific epigenetic alterations.

@en

type

label

Mll partial tandem duplication ...... ecific epigenetic alterations.

@ast

Mll partial tandem duplication ...... ecific epigenetic alterations.

@en

prefLabel

Mll partial tandem duplication ...... ecific epigenetic alterations.

@ast

Mll partial tandem duplication ...... ecific epigenetic alterations.

@en

P1433

Q35025549-3B30A1D7-45F6-4690-8711-E71764ED1763

P1476

Q35025549-FB486F11-81D4-4061-B1C8-9978F82A6FAE

P2093

Q35025549-0992F129-0426-4BD2-958F-6C7DC8805686

Q35025549-1549A78A-6CBA-4047-9C75-2A6281D5F935

Q35025549-35A6CBAC-C25B-48D4-ADA0-87660A744FAE

Q35025549-5ED60501-7BBD-48F0-BF79-52D53357FA0A

Q35025549-663AD2EC-0DBC-4659-B681-8B04DB7DFA83

Q35025549-720235AD-6148-4FFA-84AC-44BE77F2EEB1

Q35025549-7FB6739C-0B71-4EC1-BD8A-FDAB29F4DBAA

Q35025549-825C99F0-59C8-4C5F-9390-A80F2F9BC2F2

Q35025549-859C660F-9442-4E0A-9051-0872A51CCE4E

Q35025549-875EDD10-50DF-4C30-AB91-4F94EE916E3C

P2860

Q35025549-0A1182B5-3573-4709-A836-20486BB94FD3

Q35025549-0D693C07-6C0F-44A9-8DB3-1CCC52922774

Q35025549-0DD5181A-DAA2-4BCC-8D34-0DAA16D2CBE9

Q35025549-1C05F0C2-6843-4249-8D36-B4010E3D2E0C

Q35025549-2756E8F9-1BBD-443E-9816-BDB13E825100

Q35025549-2B486D51-0695-453D-B9D5-4D9BD3997944

Q35025549-33D46F1F-33B5-41BB-8720-6AD64BF817A2

Q35025549-36E506BC-5554-4CB1-808D-90C575A76887

Q35025549-383F9596-C210-488F-9ABA-CD40CDE76B61

Q35025549-39B5B731-957A-43CC-AF99-343E695DF06B

P304

Q35025549-A504BFCA-11E1-4B53-9539-CB532D844545

P31

Q35025549-0CFA94B1-DF73-4A4E-B993-5A0F26FE92DF

P356

Q35025549-E897E4F2-BDC2-4DF9-B284-CC600DBBB71D

P407

Q35025549-C4D6ECF5-F597-467C-BBA6-22DCC3C41AE8

P433

Q35025549-54D43326-E74F-4017-8A5B-F3FBD87DC7F5

P478

Q35025549-8775E93C-AA00-4CDD-8A6E-2509A135FC24

P50

Q35025549-8A4C50C8-2D5A-40A5-B46C-646E4080BFAE

P577

Q35025549-5779630E-B042-4C57-A662-8190736763C4

P5875

Q35025549-269D644C-55DF-4342-AF80-DECC9CBA4B50

P698

Q35025549-6E43169F-A9F8-4AC9-B97E-BA10F99CD7A8

P932

Q35025549-7A9CBE43-6E9A-4240-AEBD-8610DC1C379E

P356

P1433

Journal of Clinical Investigation

P1476

Mll partial tandem duplication ...... ecific epigenetic alterations.

@en

P2093

Adrienne M Dorrance

http://www.w3.org/2001/XMLSchema#string

Amy Ferketich

http://www.w3.org/2001/XMLSchema#string

Brian Becknell

http://www.w3.org/2001/XMLSchema#string

Gustavo Leone

http://www.w3.org/2001/XMLSchema#string

Kristy J Arnoczky

http://www.w3.org/2001/XMLSchema#string

Lan Feng

http://www.w3.org/2001/XMLSchema#string

Laura J Rush

http://www.w3.org/2001/XMLSchema#string

Li Yu

http://www.w3.org/2001/XMLSchema#string

Lizhao Wu

http://www.w3.org/2001/XMLSchema#string

Martin Guimond

http://www.w3.org/2001/XMLSchema#string

P2860

Translating the Histone Code

Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression

MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein

Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells

Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes

Overexpression of HOXA10 perturbs human lymphomyelopoiesis in vitro and in vivo

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning

P304

2707-2716

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1172/JCI25546

http://www.w3.org/2001/XMLSchema#string

P407

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

116

http://www.w3.org/2001/XMLSchema#string

P50

P577

2006-09-14T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6813278

http://www.w3.org/2001/XMLSchema#string

P698

16981007

http://www.w3.org/2001/XMLSchema#string

P932

1564428

http://www.w3.org/2001/XMLSchema#string