Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism.
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Pleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammationStructure and function of the ARH family of ADP-ribosyl-acceptor hydrolasesPoly (ADP-ribose) in the pathogenesis of Parkinson's diseaseThe antioxidative effect of electro-acupuncture in a mouse model of Parkinson's diseasePathophysiological Role of Peroxynitrite Induced DNA Damage in Human Diseases: A Special Focus on Poly(ADP-ribose) Polymerase (PARP)The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator functionIdentification of far upstream element-binding protein-1 as an authentic Parkin substratePoly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal deathDJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidaseLoss of locus coeruleus neurons and reduced startle in parkin null mice.Animal models of Parkinson's disease: vertebrate geneticsMacrophage-mediated GDNF delivery protects against dopaminergic neurodegeneration: a therapeutic strategy for Parkinson's disease.JNK3 mediates paraquat- and rotenone-induced dopaminergic neuron death.MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity.Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss.Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose).The effect of PARP inhibitor on ischaemic cell death, its related inflammation and survival signals.Decreased SIRT2 activity leads to altered microtubule dynamics in oxidatively-stressed neuronal cells: implications for Parkinson's disease.Targeting cellular energy production in neurological disorders.Fcγ receptors are required for NF-κB signaling, microglial activation and dopaminergic neurodegeneration in an AAV-synuclein mouse model of Parkinson's disease.The biochemical pathways of central nervous system neural degeneration in niacin deficiency.Neuronal signal transduction pathways: wasteland or the promised land?Role of Bax in death of uninfected retinal cells during murine cytomegalovirus retinitisInhibition of poly(ADP-ribose) polymerase activity is insufficient to induce tetraploidy.Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model.PARP-1 modulates amyloid beta peptide-induced neuronal damage.NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.Small peptide inhibitor of JNK3 protects dopaminergic neurons from MPTP induced injury via inhibiting the ASK1-JNK3 signaling pathwayAssociation analysis of PARP1 polymorphisms with Parkinson's disease.Parthanatos, a messenger of death.Poly(ADP-ribose) (PAR) polymer is a death signalTwo molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease.Aspects of innate immunity and Parkinson's disease.Poly(ADP-ribosyl)ation inhibitors: promising drug candidates for a wide variety of pathophysiologic conditions.D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease.Role of vitamin d in Parkinson's disease.Prevention of the degeneration of human dopaminergic neurons in an astrocyte co-culture system allowing endogenous drug metabolismCaspase-dependent and -independent neuronal death: two distinct pathways to neuronal injury.Apoptosis-inducing factor in nigral dopamine neurons: Higher levels in primates than in mice.Altered gene expression profiles reveal similarities and differences between Parkinson disease and model systems.
P2860
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P2860
Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Poly(ADP-ribose) polymerase ac ...... e (MPTP)-induced parkinsonism.
@ast
Poly(ADP-ribose) polymerase ac ...... e (MPTP)-induced parkinsonism.
@en
type
label
Poly(ADP-ribose) polymerase ac ...... e (MPTP)-induced parkinsonism.
@ast
Poly(ADP-ribose) polymerase ac ...... e (MPTP)-induced parkinsonism.
@en
altLabel
Poly(ADP-ribose) polymerase ac ...... ne (MPTP)-induced parkinsonism
@en
prefLabel
Poly(ADP-ribose) polymerase ac ...... e (MPTP)-induced parkinsonism.
@ast
Poly(ADP-ribose) polymerase ac ...... e (MPTP)-induced parkinsonism.
@en
P2093
P2860
P356
P1476
Poly(ADP-ribose) polymerase ac ...... e (MPTP)-induced parkinsonism.
@en
P2093
A S Mandir
B E Hoffman
C M Simbulan-Rosenthal
D B Guastella
M E Smulson
T M Dawson
V L Dawson
P2860
P304
P356
10.1073/PNAS.96.10.5774
P407
P577
1999-05-01T00:00:00Z