A role for neutral sphingomyelinase-mediated ceramide production in T cell receptor-induced apoptosis and mitogen-activated protein kinase-mediated signal transduction.
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Novel tumor necrosis factor-responsive mammalian neutral sphingomyelinase-3 is a C-tail-anchored proteinCeramide synthases at the centre of sphingolipid metabolism and biologyImplications of galactocerebrosidase and galactosylcerebroside metabolism in cancer cellsIdentification of Mg2+ -dependent neutral sphingomyelinase 1 as a mediator of heat stress-induced ceramide generation and apoptosis.Induction of membrane ceramides: a novel strategy to interfere with T lymphocyte cytoskeletal reorganisation in viral immunosuppression.Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism.Neutral sphingomyelinase in physiological and measles virus induced T cell suppression.Stress-induced ceramide generation and apoptosis via the phosphorylation and activation of nSMase1 by JNK signaling.Lysophosphatidylcholine as an effector of fatty acid-induced insulin resistance.The neutral sphingomyelinase pathway regulates packaging of the prion protein into exosomes.Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway.CD1b-mediated T cell recognition of a glycolipid antigen generated from mycobacterial lipid and host carbohydrate during infectionNeutral sphingomyelinase 2 (nSMase2) is the primary neutral sphingomyelinase isoform activated by tumour necrosis factor-α in MCF-7 cells.Peptidoglycan induces cyclooxygenase-2 expression in macrophages by activating the neutral sphingomyelinase-ceramide pathway.Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.Acid sphingomyelinase in macrophage biology.Inhibition of Acid Sphingomyelinase Allows for Selective Targeting of CD4+ Conventional versus Foxp3+ Regulatory T Cells.The Activity of the Neutral Sphingomyelinase Is Important in T Cell Recruitment and Directional Migration.Biochemical identification of a neutral sphingomyelinase 1 (NSM1)-like enzyme as the major NSM activity in the DT40 B-cell line: absence of a role in the apoptotic response to endoplasmic reticulum stress.Fas, ceramide and serum withdrawal induce apoptosis via a common pathway in a type II Jurkat cell line.A Functionalized Sphingolipid Analogue for Studying Redistribution during Activation in Living T Cells.Cucurbitacin E suppresses cytokine expression in human Jurkat T cells through down-regulating the NF-κB signaling.Role of acidic sphingomyelinase in Fas/CD95-mediated cell death.Neutral sphingomyelinase 2 is a key factor for PorB-dependent invasion of Neisseria gonorrhoeae.Down-regulation of anandamide hydrolase in mouse uterus by sex hormones.Cell-cycle arrest in Jurkat leukaemic cells: a possible role for docosahexaenoic acid.Chemical-physical changes in cell membrane microdomains of breast cancer cells after omega-3 PUFA incorporation.Irreversible inactivation of magnesium-dependent neutral sphingomyelinase 1 (NSM1) by peroxynitrite, a nitric oxide-derived oxidant.The Neutral Sphingomyelinase 2 Is Required to Polarize and Sustain T Cell Receptor Signaling.
P2860
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P2860
A role for neutral sphingomyelinase-mediated ceramide production in T cell receptor-induced apoptosis and mitogen-activated protein kinase-mediated signal transduction.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
A role for neutral sphingomyel ...... -mediated signal transduction.
@ast
A role for neutral sphingomyel ...... -mediated signal transduction.
@en
type
label
A role for neutral sphingomyel ...... -mediated signal transduction.
@ast
A role for neutral sphingomyel ...... -mediated signal transduction.
@en
prefLabel
A role for neutral sphingomyel ...... -mediated signal transduction.
@ast
A role for neutral sphingomyel ...... -mediated signal transduction.
@en
P2093
P2860
P356
P1476
A role for neutral sphingomyel ...... -mediated signal transduction.
@en
P2093
P2860
P304
P356
10.1084/JEM.189.10.1581
P407
P577
1999-05-01T00:00:00Z