Cysteinyl leukotrienes and uridine diphosphate induce cytokine generation by human mast cells through an interleukin 4-regulated pathway that is inhibited by leukotriene receptor antagonists
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International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapyLeukotriene E4-induced pulmonary inflammation is mediated by the P2Y12 receptorRole of ABCC1 in export of sphingosine-1-phosphate from mast cellsExpression of the type 2 receptor for cysteinyl leukotrienes (CysLT2R) by human mast cells: Functional distinction from CysLT1RMultiple P2Y receptors couple to calcium-dependent, chloride channels in smooth muscle cells of the rat pulmonary artery.Cysteinyl leukotrienes: multi-functional mediators in allergic rhinitisMultifaceted roles of cysteinyl leukotrienes in eliciting eosinophil granule protein secretionAsthma and the Risk of Rheumatoid Arthritis: An Insight into the Heterogeneity and Phenotypes of AsthmaEosinophils and Mast Cells in Aspirin-Exacerbated Respiratory Disease.Factors driving the aspirin exacerbated respiratory disease phenotype.Interleukin-4 in the Generation of the AERD Phenotype: Implications for Molecular Mechanisms Driving Therapeutic Benefit of Aspirin Desensitization.Concordant modulation of cysteinyl leukotriene receptor expression by IL-4 and IFN-gamma on peripheral immune cells.Leukotriene Inhibitors in Sinusitis.Montelukast in the treatment of duodenal eosinophilia in children with dyspepsia: effect on eosinophil density and activation in relation to pharmacokinetics.Concentration-dependent noncysteinyl leukotriene type 1 receptor-mediated inhibitory activity of leukotriene receptor antagonists.Increased expression of leukotriene C4 synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysmLeukotriene D4 and interleukin-13 cooperate to increase the release of eotaxin-3 by airway epithelial cells.Modulation of mast cell proliferative and inflammatory responses by leukotriene d4 and stem cell factor signaling interactions.The critical role of mast cells in allergy and inflammation.CysLT2 receptors interact with CysLT1 receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cells.Differential regulation of cysteinyl leukotriene receptor signaling by protein kinase C in human mast cellsMast cell CD30 ligand is upregulated in cutaneous inflammation and mediates degranulation-independent chemokine secretion.Leukotriene biosynthesis inhibition ameliorates acute lung injury following hemorrhagic shock in ratsLeukotrienes and airway inflammationMast-cell responses to pathogens.Inflammatory basis of exercise-induced bronchoconstrictionNeutrophil-derived leukotriene B4 is required for inflammatory arthritisSphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell functionMast cells in airway diseases and interstitial lung diseaseIntracrine cysteinyl leukotriene receptor-mediated signaling of eosinophil vesicular transport-mediated interleukin-4 secretionTransactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxisDisruption of the alox5ap gene ameliorates focal ischemic stroke: possible consequence of impaired leukotriene biosynthesis.Leukotriene E4 activates peroxisome proliferator-activated receptor gamma and induces prostaglandin D2 generation by human mast cells.Differential release of mast cell mediators and the pathogenesis of inflammation.Mast cells and eicosanoid mediators: a system of reciprocal paracrine and autocrine regulation.Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine productionP2Y6 receptors require an intact cysteinyl leukotriene synthetic and signaling system to induce survival and activation of mast cells.CysLT1 leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors.GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4.Novel methylxanthine derivative-mediated anti-inflammatory effects in inflammatory bowel disease.
P2860
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P2860
Cysteinyl leukotrienes and uridine diphosphate induce cytokine generation by human mast cells through an interleukin 4-regulated pathway that is inhibited by leukotriene receptor antagonists
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
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2002年學術文章
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name
Cysteinyl leukotrienes and uri ...... ukotriene receptor antagonists
@ast
Cysteinyl leukotrienes and uri ...... ukotriene receptor antagonists
@en
type
label
Cysteinyl leukotrienes and uri ...... ukotriene receptor antagonists
@ast
Cysteinyl leukotrienes and uri ...... ukotriene receptor antagonists
@en
prefLabel
Cysteinyl leukotrienes and uri ...... ukotriene receptor antagonists
@ast
Cysteinyl leukotrienes and uri ...... ukotriene receptor antagonists
@en
P2093
P2860
P356
P1476
Cysteinyl leukotrienes and uri ...... ukotriene receptor antagonists
@en
P2093
Elizabeth A Mellor
Joshua A Boyce
K Frank Austen
P2860
P304
P356
10.1084/JEM.20020044
P407
P577
2002-03-01T00:00:00Z