GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4. - Wikidata - awgldk - TriplyDB

GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4.

GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4.

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International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer Cysteinyl leukotrienes and their receptors; emerging concepts Cysteinyl Leukotrienes and Their Receptors: Emerging Therapeutic Targets in Central Nervous System Disorders Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7 GPR17 regulates immune pulmonary inflammation induced by house dust mites Leukotriene Inhibitors in Sinusitis.The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors Forced unbinding of GPR17 ligands from wild type and R255I mutant receptor models through a computational approach.Role of Leukotrienes and Leukotriene Modifiers in Asthma.Decoding signaling and function of the orphan G protein-coupled receptor GPR17 with a small-molecule agonist Cysteinyl leukotriene signaling aggravates myocardial hypoxia in experimental atherosclerotic heart disease Increased expression of leukotriene C4 synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm The G Protein-Coupled Receptor GPR17: Overview and Update.Enigmatic GPCR finds a stimulating drug.Leukotrienes and airway inflammation Cysteinyl leukotriene 2 receptor on dendritic cells negatively regulates ligand-dependent allergic pulmonary inflammation.The regulated expression, intracellular trafficking, and membrane recycling of the P2Y-like receptor GPR17 in Oli-neu oligodendroglial cells.An eicosanoid-centric view of atherothrombotic risk factors Changes of the GPR17 receptor, a new target for neurorepair, in neurons and glial cells in patients with traumatic brain injury.Is GPR17 a P2Y/leukotriene receptor? examination of uracil nucleotides, nucleotide sugars, and cysteinyl leukotrienes as agonists of GPR17.Leukotriene B4 receptor type 2 protects against pneumolysin-dependent acute lung injury.Intercellular Lipid Mediators and GPCR Drug Discovery Expression of GPR17, a regulator of oligodendrocyte differentiation and maturation, in Nasu-Hakola disease brains.Interactions between prostaglandins, leukotrienes and HIV-1: possible implications for the central nervous system.Eicosanoids and their drugs in cardiovascular diseases: focus on atherosclerosis and stroke.Cysteinyl leukotriene receptors, old and new; implications for asthma.Proinflammatory and immunoregulatory roles of eicosanoids in T cells.Pharmacological Properties and Biological Functions of the GPR17 Receptor, a Potential Target for Neuro-Regenerative Medicine.Molecular mechanisms of target recognition by lipid GPCRs: relevance for cancer.Cysteinyl Leukotrienes as Potential Pharmacological Targets for Cerebral Diseases.Extracellular cues influencing oligodendrocyte differentiation and (re)myelination Leukotriene D4 and prostaglandin E2 signals synergize and potentiate vascular inflammation in a mast cell-dependent manner through cysteinyl leukotriene receptor 1 and E-prostanoid receptor 3.Distinct expression and ligand-binding profiles of two constitutively active GPR17 splice variants.Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity.Pharmacological characterization of the first potent and selective antagonist at the cysteinyl leukotriene 2 (CysLT(2)) receptor.A role for inflammatory mediators in heterologous desensitization of CysLT1 receptor in human monocytes.Development of [(3)H]2-Carboxy-4,6-dichloro-1H-indole-3-propionic Acid ([(3)H]PSB-12150): A Useful Tool for Studying GPR17 Cysteinyl Leukotrienes in Eosinophil Biology: Functional Roles and Therapeutic Perspectives in Eosinophilic Disorders Role of the Cysteinyl Leukotrienes in the Pathogenesis and Progression of Cardiovascular Diseases.

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GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4.

http://www.wikidata.org/entity/Q37261678

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 26 June 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

GPR17 is a negative regulator ...... or response to leukotriene D4.

@en

GPR17 is a negative regulator ...... or response to leukotriene D4.

@nl

type

label

GPR17 is a negative regulator ...... or response to leukotriene D4.

@en

GPR17 is a negative regulator ...... or response to leukotriene D4.

@nl

prefLabel

GPR17 is a negative regulator ...... or response to leukotriene D4.

@en

GPR17 is a negative regulator ...... or response to leukotriene D4.

@nl

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PNAS.0905364106

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Proceedings of the National Academy of Sciences of the United States of America

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GPR17 is a negative regulator ...... tor response to leukotriene D4

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Akiko Maekawa

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K Frank Austen

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Yoshihide Kanaoka

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P2860

Heterodimerization is required for the formation of a functional GABA(B) receptor

Characterization of the human cysteinyl leukotriene CysLT1 receptor

The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization

Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis

Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein

New members of the chemokine receptor gene family

Airway smooth muscle prostaglandin-EP1 receptors directly modulate beta2-adrenergic receptors within a unique heterodimeric complex

Conversion of leukotriene D4 to leukotriene E4 by a dipeptidase released from the specific granule of human polymorphonuclear leucocytes

Different functional roles of T1R subunits in the heteromeric taste receptors

Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors

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11685-11690

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scholarly article

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10.1073/PNAS.0905364106

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28

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106

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Barbara Balestrieri

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2009-06-26T00:00:00Z

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26325415

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19561298

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G protein-coupled receptor 17

Cysteinyl leukotriene receptor 1

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2710631

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