The earliest step in B lineage differentiation from common lymphoid progenitors is critically dependent upon interleukin 7
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Distinct gene expression profiles in different B-cell compartments in human peripheral lymphoid organsAgeing, autoimmunity and arthritis: senescence of the B cell compartment - implications for humoral immunityc-Myb is required for pro-B cell differentiation.The adaptor protein Shc plays a key role during early B cell developmentComplementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesisTranscriptional repressor Gfi1 integrates cytokine-receptor signals controlling B-cell differentiation.A conserved gene family encodes transmembrane proteins with fibronectin, immunoglobulin and leucine-rich repeat domains (FIGLER).Contingent gene regulatory networks and B cell fate specificationA reporter mouse reveals lineage-specific and heterogeneous expression of IRF8 during lymphoid and myeloid cell differentiation.Use of interleukin 7 receptor-alpha knockout donor cells demonstrates the lymphoid independence of dendritic cellsAnalysis of the role of IL-21 in development of murine B cell progenitors in the bone marrow.Separation of plasmacytoid dendritic cells from B-cell-biased lymphoid progenitor (BLP) and Pre-pro B cells using PDCA-1.B-cell antigen-receptor signalling in lymphocyte development.Bone marrow and the control of immunity.Computational Modeling of a Transcriptional Switch Underlying B-Lymphocyte Lineage Commitment of Hematopoietic Multipotent Cells.Regulation of immunoglobulin heavy-chain gene rearrangements.Mouse plasmacytoid dendritic cells derive exclusively from estrogen-resistant myeloid progenitorsPax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments.Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1Lineage specification and plasticity in CD19- early B cell precursors.Regulation of intrathymic T-cell development by Lunatic Fringe- Notch1 interactions.Loss of Bim allows precursor B cell survival but not precursor B cell differentiation in the absence of interleukin 7From stem cell to T cell: one route or many?Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitorsIL-7 receptor signaling is necessary for stage transition in adult B cell development through up-regulation of EBF.Cbfbeta-SMMHC impairs differentiation of common lymphoid progenitors and reveals an essential role for RUNX in early B-cell development.Sox4 is required for the survival of pro-B cells.Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineagesReciprocal patterns of methylation of H3K36 and H3K27 on proximal vs. distal IgVH genes are modulated by IL-7 and Pax5.B cells and aging: balancing the homeostatic equationLin-Sca1+kit- bone marrow cells contain early lymphoid-committed precursors that are distinct from common lymphoid progenitorsEbf1-mediated down-regulation of Id2 and Id3 is essential for specification of the B cell lineageInteractions between B lymphocytes and the osteoblast lineage in bone marrow.Ethanol exhibits specificity in its effects on differentiation of hematopoietic progenitors.Acute lymphoblastic leukemia and developmental biology: a crucial interrelationshipInterleukin 7 and thymic stromal lymphopoietin: from immunity to leukemia.Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5.Determination of lymphoid cell fate is dependent on the expression status of the IL-7 receptor.Signaling proteins and transcription factors in normal and malignant early B cell development.Modulation of PKC-α promotes lineage reprogramming of committed B lymphocytes.
P2860
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P2860
The earliest step in B lineage differentiation from common lymphoid progenitors is critically dependent upon interleukin 7
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
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2002年學術文章
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name
The earliest step in B lineage ...... y dependent upon interleukin 7
@ast
The earliest step in B lineage ...... y dependent upon interleukin 7
@en
type
label
The earliest step in B lineage ...... y dependent upon interleukin 7
@ast
The earliest step in B lineage ...... y dependent upon interleukin 7
@en
prefLabel
The earliest step in B lineage ...... y dependent upon interleukin 7
@ast
The earliest step in B lineage ...... y dependent upon interleukin 7
@en
P2093
P2860
P356
P1476
The earliest step in B lineage ...... y dependent upon interleukin 7
@en
P2093
Avinash Bhandoola
David Allman
David Izon
Juli P Miller
Rachel Gerstein
William DeMuth
P2860
P304
P356
10.1084/JEM.20020784
P407
P577
2002-09-01T00:00:00Z