Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5.
about
Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5Long-Range Regulation of V(D)J RecombinationOrchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signallingHigher order chromatin organization in cancerRAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin lociSilencing and nuclear repositioning of the lambda5 gene locus at the pre-B cell stage requires Aiolos and OBF-1.Interferon regulatory factor 4 and 8 in B-cell development.Lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitorsStat5a/b are essential for normal lymphoid development and differentiation.Profiling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia.The NAMPT promoter is regulated by mechanical stress, signal transducer and activator of transcription 5, and acute respiratory distress syndrome-associated genetic variants.OCT1 is a determinant of synbindin-related ERK signalling with independent prognostic significance in gastric cancerModulation of peripheral T-cell function by interleukin-7 in rheumatoid arthritis.Cis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus.IL-7R expression and IL-7 signaling confer a distinct phenotype on developing human B-lineage cells.Yin Yang 1 is a critical regulator of B-cell developmentSTAT3 positively regulates an early step in B-cell development.Chromosomal position of a VH gene segment determines its activation and inactivation as a substrate for V(D)J recombination.Integrated signaling in developing lymphocytes: the role of DNA damage responses.Loss of Bcl-x in Ph+ B-ALL increases cellular proliferation and does not inhibit leukemogenesisRAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals.Reciprocal patterns of methylation of H3K36 and H3K27 on proximal vs. distal IgVH genes are modulated by IL-7 and Pax5.Lymphocyte development: integration of DNA damage response signaling.Localized epigenetic changes induced by DH recombination restricts recombinase to DJH junctionsEpigenetics of antigen-receptor gene assembly.New insights into the roles of Stat5a/b and Stat3 in T cell development and differentiation.Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiationEffects of acute and chronic inflammation on B-cell development and differentiation.Hoxa9 regulates Flt3 in lymphohematopoietic progenitors.IL-7-producing stromal cells are critical for lymph node remodelingEpigenetic regulation of V(D)J recombination.The role of STAT5 in the development, function, and transformation of B and T lymphocytes.Harnessing the biology of IL-7 for therapeutic application.The role of STAT5 in lymphocyte development and transformationRas orchestrates exit from the cell cycle and light-chain recombination during early B cell development.Signaling proteins and transcription factors in normal and malignant early B cell development.Evidence for a protective role of the STAT5 transcription factor against oxidative stress in human leukemic pre-B cells.A developmentally controlled competitive STAT5-PU.1 DNA binding mechanism regulates activity of the Ig κ E3' enhancer.A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation
P2860
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P2860
Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Regulation of interleukin 7-de ...... by transcription factor STAT5.
@en
type
label
Regulation of interleukin 7-de ...... by transcription factor STAT5.
@en
prefLabel
Regulation of interleukin 7-de ...... by transcription factor STAT5.
@en
P2093
P2860
P356
P1433
P1476
Regulation of interleukin 7-de ...... by transcription factor STAT5.
@en
P2093
Eric Bertolino
Evan Parganas
Harinder Singh
James Ihle
Karen Reddy
Kay L Medina
P2860
P304
P356
10.1038/NI1226
P407
P577
2005-07-17T00:00:00Z