Interleukin 2 receptor signaling regulates the perforin gene through signal transducer and activator of transcription (Stat)5 activation of two enhancers
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Cytotoxic CD4 T cells in antiviral immunityDifferential effects of IL-21 and IL-15 on perforin expression, lysosomal degranulation, and proliferation in CD8 T cells of patients with human immunodeficiency virus-1 (HIV)Methods for analyzing the role of DNA methylation and chromatin structure in regulating T lymphocyte gene expressionA reliable method to display authentic DNase I hypersensitive sites at long-ranges in single-copy genes from large genomesThe immunological and clinical effects of mutated ras peptide vaccine in combination with IL-2, GM-CSF, or both in patients with solid tumors.Determination of quantitative and site-specific DNA methylation of perforin by pyrosequencingInterleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells.STAT5 is critical to maintain effector CD8+ T cell responses.Monocyte chemoattractant protein-1 secreted by decidual stromal cells inhibits NK cells cytotoxicity by up-regulating expression of SOCS3.Acute psychosocial stress-mediated changes in the expression and methylation of perforin in chronic fatigue syndrome.Cytokines and immunodeficiency diseases.High-resolution nucleosome mapping of targeted regions using BAC-based enrichmentMolecular mechanisms influencing NK cell development: implications for NK cell malignancies.Inflammation enhances IL-2 driven differentiation of cytolytic CD4 T cells.Multifunctional human immunodeficiency virus (HIV) gag-specific CD8+ T-cell responses in rectal mucosa and peripheral blood mononuclear cells during chronic HIV type 1 infection.Detection and characterization of a novel subset of CD8⁺CD57⁺ T cells in metastatic melanoma with an incompletely differentiated phenotype.Cord blood PRF1 methylation patterns and risk of lower respiratory tract infections in infants: findings from the Ulm Birth CohortReduced PRF1 enhancer methylation in children with a history of severe RSV bronchiolitis in infancy: an association study.At the crossroads: diverse roles of early thymocyte transcriptional regulators.The transcriptional control of the perforin locusEpigenetic regulation of NK cell differentiation and effector functions.Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs.CD4+ T cells are required for the priming of CD8+ T cells following infection with herpes simplex virus type 1.Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation.Psychologic stress, reduced NK cell activity, and cytokine dysregulation in women experiencing diagnostic breast biopsy.The battlefield of perforin/granzyme cell death pathways.Cytolytic CD4 cells: Direct mediators in infectious disease and malignancy.The roles of c-rel and interleukin-2 in tolerance: a molecular explanation of self-nonself discrimination.Cytolytic CD4(+) T cells in viral immunityPromoting Immune Regulation in Type 1 Diabetes Using Low-Dose Interleukin-2.The lytic potential of human liver NK cells is restricted by their limited expression of inhibitory killer Ig-like receptors.Selective Destruction of Interleukin 23-Induced Expansion of a Major Antigen-Specific γδ T-Cell Subset in Patients With Tuberculosis.Administration of DNA Encoding the Interleukin-27 Gene Augments Antitumour Responses through Non-adaptive Immunity.IL-21 augments natural killer effector functions in chronically HIV-infected individuals.Novel polymorphisms in the promoter region of the perforin gene among distinct Brazilian populations and their functional impact.Interleukin-21 and cellular activation concurrently induce potent cytotoxic function and promote antiviral activity in human CD8 T cellsIL-2 and antigen dose differentially regulate perforin- and FasL-mediated cytolytic activity in antigen specific CD4+ T cells.Induction of granulysin in CD8+ T cells by IL-21 and IL-15 is suppressed by human immunodeficiency virus-1.Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations.Role of STAT5 and epigenetics in lactation-associated upregulation of multidrug transporter ABCG2 in the mammary gland.
P2860
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P2860
Interleukin 2 receptor signaling regulates the perforin gene through signal transducer and activator of transcription (Stat)5 activation of two enhancers
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Interleukin 2 receptor signali ...... )5 activation of two enhancers
@ast
Interleukin 2 receptor signali ...... )5 activation of two enhancers
@en
type
label
Interleukin 2 receptor signali ...... )5 activation of two enhancers
@ast
Interleukin 2 receptor signali ...... )5 activation of two enhancers
@en
prefLabel
Interleukin 2 receptor signali ...... )5 activation of two enhancers
@ast
Interleukin 2 receptor signali ...... )5 activation of two enhancers
@en
P2093
P2860
P356
P1476
Interleukin 2 receptor signali ...... )5 activation of two enhancers
@en
P2093
M G Lichtenheld
P2860
P304
P356
10.1084/JEM.190.9.1297
P407
P577
1999-11-01T00:00:00Z