Mapping the energy of superantigen Staphylococcus enterotoxin C3 recognition of an alpha/beta T cell receptor using alanine scanning mutagenesis.
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Assessing Energetic Contributions to Binding from a Disordered Region in a Protein−Protein Interaction,Molecular Basis of a Million-Fold Affinity Maturation Process in a Protein–Protein InteractionStructural basis of affinity maturation and intramolecular cooperativity in a protein-protein interactionSurvey of the year 2000 commercial optical biosensor literature.The T cell receptor beta-chain second complementarity determining region loop (CDR2beta governs T cell activation and Vbeta specificity by bacterial superantigensEngineering a soluble high-affinity receptor domain that neutralizes staphylococcal enterotoxin C in rabbit models of diseaseSoluble T cell receptor Vβ domains engineered for high-affinity binding to staphylococcal or streptococcal superantigensA serine/threonine phosphorylation site in the ectodomain of a T cell receptor beta chain is required for activation by superantigen.Role of the T cell receptor ligand affinity in T cell activation by bacterial superantigens.A single, engineered protein therapeutic agent neutralizes exotoxins from both Staphylococcus aureus and Streptococcus pyogenes.Dissecting cooperative and additive binding energetics in the affinity maturation pathway of a protein-protein interface.
P2860
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P2860
Mapping the energy of superantigen Staphylococcus enterotoxin C3 recognition of an alpha/beta T cell receptor using alanine scanning mutagenesis.
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2000 nî lūn-bûn
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Mapping the energy of superant ...... alanine scanning mutagenesis.
@ast
Mapping the energy of superant ...... alanine scanning mutagenesis.
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type
label
Mapping the energy of superant ...... alanine scanning mutagenesis.
@ast
Mapping the energy of superant ...... alanine scanning mutagenesis.
@en
prefLabel
Mapping the energy of superant ...... alanine scanning mutagenesis.
@ast
Mapping the energy of superant ...... alanine scanning mutagenesis.
@en
P2093
P2860
P356
P1476
Mapping the energy of superant ...... alanine scanning mutagenesis.
@en
P2093
H R Churchill
P S Andersen
R A Mariuzza
P2860
P304
P356
10.1084/JEM.191.5.835
P407
P577
2000-03-01T00:00:00Z