Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages
about
Viperin (cig5), an IFN-inducible antiviral protein directly induced by human cytomegalovirusSpecific dysregulation of IFNγ production by natural killer cells confers susceptibility to viral infectionLatent gammaherpesvirus 68 infection induces distinct transcriptional changes in different organsTonsilar NK cells restrict B cell transformation by the Epstein-Barr virus via IFN-gamma.Murine cytomegalovirus paralyzes macrophages by blocking IFN gamma-induced promoter assembly.Identification of DNA-damage DNA-binding protein 1 as a conditional essential factor for cytomegalovirus replication in interferon-γ-stimulated cells.A gammaherpesvirus cooperates with interferon-alpha/beta-induced IRF2 to halt viral replication, control reactivation, and minimize host lethality.Lack of XBP-1 impedes murine cytomegalovirus gene expression.IFNγ inhibits the cytosolic replication of Shigella flexneri via the cytoplasmic RNA sensor RIG-I.Post-genomic virology: the impact of bioinformatics, microarrays and proteomics on investigating host and pathogen interactions.Searching for interferon-induced genes that inhibit hepatitis B virus replication in transgenic mouse hepatocytes.CD8 T cells control cytomegalovirus latency by epitope-specific sensing of transcriptional reactivationReversible inhibition of murine cytomegalovirus replication by gamma interferon (IFN-γ) in primary macrophages involves a primed type I IFN-signaling subnetwork for full establishment of an immediate-early antiviral state.Coordinate regulation of DNA damage and type I interferon responses imposes an antiviral state that attenuates mouse gammaherpesvirus type 68 replication in primary macrophages.Cytomegalovirus impairs antiviral CD8+ T cell immunity by recruiting inflammatory monocytes.Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta.Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages.Gamma interferon blocks gammaherpesvirus reactivation from latency in a cell type-specific manner.Noncytotoxic functions of NK cells: direct pathogen restriction and assistance to adaptive immunity.Natural killer cells in immunodefense against infective agents.Interplay between CMVs and interferon signaling: implications for pathogenesis and therapeutic intervention.Preactivation of the interferon signalling in liver is correlated with nonresponse to interferon alpha therapy in patients chronically infected with hepatitis B virus.Immune control of the number and reactivation phenotype of cells latently infected with a gammaherpesvirus.Effective inhibition of K(b)- and D(b)-restricted antigen presentation in primary macrophages by murine cytomegalovirus.Murine cytomegalovirus infection inhibits tumor necrosis factor alpha responses in primary macrophages.Natural killer cells utilize both perforin and gamma interferon to regulate murine cytomegalovirus infection in the spleen and liver.Coimmunisation with type I IFN genes enhances protective immunity against cytomegalovirus and myocarditis in gB DNA-vaccinated mice.Type I interferon gene therapy protects against cytomegalovirus-induced myocarditis.Gamma-interferon exerts a critical early restriction on replication and dissemination of yellow fever virus vaccine strain 17D-204.Murine cytomegalovirus degrades MHC class II to colonize the salivary glands.Immune-regulatory transcriptional responses in multiple organs of Atlantic salmon after tributyltin exposure, alone or in combination with forskolin.Control of primary mouse cytomegalovirus infection in lung nodular inflammatory foci by cooperation of interferon-gamma expressing CD4 and CD8 T cells
P2860
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P2860
Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages
description
2001 nî lūn-bûn
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
@zh-my
2001年学术文章
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2001年學術文章
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2001年學術文章
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2001年學術文章
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name
Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages
@ast
Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages
@en
type
label
Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages
@ast
Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages
@en
prefLabel
Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages
@ast
Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages
@en
P2093
P2860
P356
P1476
Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages
@en
P2093
D L Popkin
H W Virgin
R M Presti
S Paetzold
P2860
P304
P356
10.1084/JEM.193.4.483
P407
P577
2001-02-01T00:00:00Z