CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer
about
Regulatory function of a novel population of mouse autoantigen-specific Foxp3 regulatory T cells depends on IFN-gamma, NO, and contact with target cells.Glutamic acid decarboxylase-derived epitopes with specific domains expand CD4(+)CD25(+) regulatory T cells.Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cellsTGF-beta signaling is required for the function of insulin-reactive T regulatory cellsAge-dependent loss of tolerance to an immunodominant epitope of glutamic acid decarboxylase in diabetic-prone RIP-B7/DR4 mice.Specific antigen vaccination to treat autoimmune disease.Targeting T lymphocytes for immune monitoring and intervention in autoimmune diabetes.Normal incidence of diabetes in NOD mice tolerant to glutamic acid decarboxylase.In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes.CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.Massive thymic deletion results in systemic autoimmunity through elimination of CD4+ CD25+ T regulatory cells.Regulatory T cells in lupus.Autoreactive human T-cell receptor initiates insulitis and impaired glucose tolerance in HLA DR4 transgenic mice.Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes.T-cell promiscuity in autoimmune diabetes.Recombinase-activating gene 1-associated expression of the myelin basic protein 1-11-specific transgenic T-cell receptor in H-2b mice.Efficient Presentation of Multiple Endogenous Epitopes to Both CD4+ and CD8+ Diabetogenic T Cells for ToleranceCD52 as both a marker and an effector molecule of T cells with regulatory action: Identification of novel regulatory T cells.T-cell autoantigens in the non-obese diabetic mouse model of autoimmune diabetes.Antigen-specific therapy against type 1 diabetes: mechanisms and perspectives.Vaccination with a co-expression DNA plasmid containing GAD65 fragment gene and IL-10 gene induces regulatory CD4(+) T cells that prevent experimental autoimmune diabetes.Autoreactive T cells in a partially humanized murine model of T1D.Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs.Regulatory cytokine production stimulated by DNA vaccination against an altered form of glutamic acid decarboxylase 65 in nonobese diabetic mice.Antigen-Specific T Cell Analysis Reveals That Active Immune Responses to β Cell Antigens Are Focused on a Unique Set of Epitopes.
P2860
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P2860
CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer
description
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name
CD4(+) T cells from glutamic a ...... nd can delay diabetes transfer
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CD4(+) T cells from glutamic a ...... nd can delay diabetes transfer
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type
label
CD4(+) T cells from glutamic a ...... nd can delay diabetes transfer
@ast
CD4(+) T cells from glutamic a ...... nd can delay diabetes transfer
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prefLabel
CD4(+) T cells from glutamic a ...... nd can delay diabetes transfer
@ast
CD4(+) T cells from glutamic a ...... nd can delay diabetes transfer
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P2093
P2860
P356
P1476
CD4(+) T cells from glutamic a ...... nd can delay diabetes transfer
@en
P2093
Cheng Chi Chao
Erik Ranheim
Hugh McDevitt
Kristin V Tarbell
Luc Teyton
Maija Sanna
Mark Davis
Peter Dickie
Seon-Kyeong Kim
P2860
P304
P356
10.1084/JEM.20011845
P407
P577
2002-08-01T00:00:00Z