about
Suppression of ongoing T cell-mediated autoimmunity by peptide-MHC class II dimer vaccination.Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responsesCentral nervous system destruction mediated by glutamic acid decarboxylase-specific CD4+ T cells.Autoreactive effector/memory CD4+ and CD8+ T cells infiltrating grafted and endogenous islets in diabetic NOD mice exhibit similar T cell receptor usage.Spectratyping analysis of the islet-reactive T cell repertoire in diabetic NOD Igμ(null) mice after polyclonal B cell reconstitutionCumulative autoimmunity: T cell clones recognizing several self-epitopes exhibit enhanced pathogenicityEpitope-specificity of recombinant antibodies reveals promiscuous peptide-binding properties.T cell populations in the pancreatic lymph node naturally and consistently expand and contract in NOD mice as disease progresses.Mechanisms of autoimmunity in the non-obese diabetic mouse: effector/regulatory cell equilibrium during peak inflammation.Generation of β cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice.Downregulation of TGF-βRII in T effector cells leads to increased resistance to TGF-β-mediated suppression of autoimmune responses in type I diabetes.T Cell-Mediated Beta Cell Destruction: Autoimmunity and Alloimmunity in the Context of Type 1 Diabetes.CD40 engagement of CD4+ CD40+ T cells in a neo-self antigen disease model ablates CTLA-4 expression and indirectly impacts tolerance
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
T-cell promiscuity in autoimmune diabetes.
@ast
T-cell promiscuity in autoimmune diabetes.
@en
type
label
T-cell promiscuity in autoimmune diabetes.
@ast
T-cell promiscuity in autoimmune diabetes.
@en
prefLabel
T-cell promiscuity in autoimmune diabetes.
@ast
T-cell promiscuity in autoimmune diabetes.
@en
P2093
P2860
P356
P1433
P1476
T-cell promiscuity in autoimmune diabetes.
@en
P2093
Jeffrey A Frelinger
Roland Tisch
P2860
P304
P356
10.2337/DB08-0383
P407
P577
2008-05-20T00:00:00Z