Piperlongumine induces rapid depletion of the androgen receptor in human prostate cancer cells
about
A sting in the tail: the N-terminal domain of the androgen receptor as a drug targetActivity of alkaloids on peptic ulcer: what's new?Evaluation of the efficacy & biochemical mechanism of cell death induction by Piper longum extract selectively in in-vitro and in-vivo models of human cancer cellsAnticancer principles from medicinal piper ( hú jiāo) plants.Piperlongumine inhibits NF-κB activity and attenuates aggressive growth characteristics of prostate cancer cellsPiperlongumine inhibits migration of glioblastoma cells via activation of ROS-dependent p38 and JNK signaling pathways.Piperlongumine induces apoptotic and autophagic death of the primary myeloid leukemia cells from patients via activation of ROS-p38/JNK pathways.High-throughput screen of natural product libraries for hsp90 inhibitors.Advances in the research and development of natural health products as main stream cancer therapeuticsDiscovery of piperlongumine as a potential novel lead for the development of senolytic agents.Piperlongumine and its analogs down-regulate expression of c-Met in renal cell carcinoma.Piperlongumine inhibits atherosclerotic plaque formation and vascular smooth muscle cell proliferation by suppressing PDGF receptor signaling.An improved quantitative approach for the assessment of mitochondrial fragmentation in chemoresistant ovarian cancer cells.Piperlongumine induces autophagy by targeting p38 signaling.Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death.Detoxification of oxidative stress in glioma stem cells: mechanism, clinical relevance, and therapeutic development.Piperlongumine induces apoptosis and autophagy in human lung cancer cells through inhibition of PI3K/Akt/mTOR pathway.Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells.Biodegradable nanoassemblies of piperlongumine display enhanced anti-angiogenesis and anti-tumor activities.The Clinical Potential of Senolytic Drugs.Optimization and comprehensive characterization of a faithful tissue culture model of the benign and malignant human prostate.A novel platinum complex containing a piplartine derivative exhibits enhanced cytotoxicity, causes oxidative stress and triggers apoptotic cell death by ERK/p38 pathway in human acute promyelocytic leukemia HL-60 cellsTargeting senescence to delay progression of multiple sclerosis
P2860
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P2860
Piperlongumine induces rapid depletion of the androgen receptor in human prostate cancer cells
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
Piperlongumine induces rapid d ...... in human prostate cancer cells
@ast
Piperlongumine induces rapid d ...... in human prostate cancer cells
@en
type
label
Piperlongumine induces rapid d ...... in human prostate cancer cells
@ast
Piperlongumine induces rapid d ...... in human prostate cancer cells
@en
prefLabel
Piperlongumine induces rapid d ...... in human prostate cancer cells
@ast
Piperlongumine induces rapid d ...... in human prostate cancer cells
@en
P2093
P2860
P356
P1433
P1476
Piperlongumine induces rapid d ...... in human prostate cancer cells
@en
P2093
Alexander Kutikov
Daniel Canter
Ervin Teper
Konstantin V Golovine
Peter B Makhov
Robert G Uzzo
Vladimir M Kolenko
P2860
P356
10.1002/PROS.22535
P577
2012-05-16T00:00:00Z