about
Targeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2Cell cycle-regulated trafficking of human telomerase to telomeresControl of human telomere length by TRF1 and TRF2Telomere dysfunction and chromosome instabilityHistone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradationTelomere-mediated chromosomal truncation in maizeHuman MLH1 suppresses the insertion of telomeric sequences at intra-chromosomal sites in telomerase-expressing cells.Irradiation-induced telomerase activity and gastric cancer risk: a case-control analysis in a Chinese Han population.Effect of telomere proximity on telomere position effect, chromosome healing, and sensitivity to DNA double-strand breaks in a human tumor cell line.Quantitative theory of telomere length regulation and cellular senescenceThe telomerase reverse transcriptase regulates chromatin state and DNA damage responses.Multiple pathways for repair of DNA double-strand breaks in mammalian chromosomesIncreased sensitivity of subtelomeric regions to DNA double-strand breaks in a human cancer cell lineTelomerase contributes to tumorigenesis by a telomere length-independent mechanism.Telomere loss as a mechanism for chromosome instability in human cancerChromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cellsTelomere position effect and silencing of transgenes near telomeres in the mouse.Telomeres, chromosome instability and cancerNatural variation in a subtelomeric region of Arabidopsis: implications for the genomic dynamics of a chromosome end.DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line.The relationship between spontaneous telomere loss and chromosome instability in a human tumor cell line.Subtelomeric regions in mammalian cells are deficient in DNA double-strand break repair.Chk2 and p53 regulate the transmission of healed chromosomes in the Drosophila male germline.PIF1 disruption or NBS1 hypomorphism does not affect chromosome healing or fusion resulting from double-strand breaks near telomeres in murine embryonic stem cells.Mechanisms of telomere loss and their consequences for chromosome instability.Chromosome healing by de novo telomere addition in Saccharomyces cerevisiae.Epigenetic and phenotypic consequences of a truncation disrupting the imprinted domain on distal mouse chromosome 7.Redox regulation of multidrug resistance in cancer chemotherapy: molecular mechanisms and therapeutic opportunitiesTelomerase-dependent and -independent chromosome healing in mouse embryonic stem cellsCancer therapy-induced residual bone marrow injury-Mechanisms of induction and implication for therapy.Insertion of telomeric repeats at intrachromosomal break sites during primate evolution.Chromosome healing through terminal deletions generated by de novo telomere additions in Saccharomyces cerevisiae.Regulation of telomere addition at DNA double-strand breaks.Deletion of a trypanosome telomere leads to loss of silencing and progressive loss of terminal DNA in the absence of cell cycle arrest.Telomere maintenance and length regulation in Trypanosoma brucei.De novo telomere formation is suppressed by the Mec1-dependent inhibition of Cdc13 accumulation at DNA breaks.Fusion of short telomeres in human cells is characterized by extensive deletion and microhomology, and can result in complex rearrangements.Protection of internal (TTAGGG)n repeats in Chinese hamster cells by telomeric protein TRF1.Subnuclear shuttling of human telomerase induced by transformation and DNA damage.Rapid upregulation of telomerase activity in human leukemia HL-60 cells treated with clinical doses of the DNA-damaging drug etoposide.
P2860
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P2860
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Chromosome healing in mouse embryonic stem cells.
@ast
Chromosome healing in mouse embryonic stem cells.
@en
type
label
Chromosome healing in mouse embryonic stem cells.
@ast
Chromosome healing in mouse embryonic stem cells.
@en
prefLabel
Chromosome healing in mouse embryonic stem cells.
@ast
Chromosome healing in mouse embryonic stem cells.
@en
P2093
P2860
P356
P1476
Chromosome healing in mouse embryonic stem cells.
@en
P2093
C N Sprung
G E Reynolds
J P Murnane
P2860
P304
P356
10.1073/PNAS.96.12.6781
P407
P577
1999-06-01T00:00:00Z