The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma.
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RASSF6; the Putative Tumor Suppressor of the RASSF FamilyRASSF tumor suppressor gene family: biological functions and regulationpETM: a penalized Exponential Tilt Model for analysis of correlated high-dimensional DNA methylation data.RASSF6 promotes p21(Cip1/Waf1)-dependent cell cycle arrest and apoptosis through activation of the JNK/SAPK pathway in clear cell renal cell carcinoma.Silencing of RASSF3 by DNA hypermethylation is associated with tumorigenesis in somatotroph adenomas.Promoter methylation status of Ras-association domain family members in pheochromocytoma.RASSF10 suppresses colorectal cancer growth by activating P53 signaling and sensitizes colorectal cancer cell to docetaxel.Low RASSF6 expression in pancreatic ductal adenocarcinoma is associated with poor survival.RASSF10 suppresses hepatocellular carcinoma growth by activating P53 signaling and methylation of RASSF10 is a docetaxel resistant markerRASSF6 exhibits promoter hypermethylation in metastatic melanoma and inhibits invasion in melanoma cells.Genome-wide methylation profiling identifies novel methylated genes in neuroblastoma tumorsDecreased level of RASSF6 in sporadic colorectal cancer and its anti-tumor effects both in vitro and in vivoGenetic and epigenetic mutations of tumor suppressive genes in sporadic pituitary adenomaIntegrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma.Differential expression profiling of microRNAs in para-carcinoma, carcinoma and relapse human pancreatic cancer.Principles of K-Ras effector organization and the role of oncogenic K-Ras in cancer initiation through G1 cell cycle deregulation.Ras signaling through RASSF proteins.RASSF5A, a candidate tumor suppressor, is epigenetically inactivated in esophageal squamous cell carcinoma.Hepatitis B virus X protein accelerates hepatocarcinogenesis with partner survivin through modulating miR-520b and HBXIP.Aberrant promoter methylation and silencing of RASSF2A gene in cervical cancer.The E3 ubiquitin ligase Itch regulates tumor suppressor protein RASSF5/NORE1 stability in an acetylation-dependent manner.Transcriptome sequencing reveals a profile that corresponds to genomic variants in Waldenström macroglobulinemia.BCL-XL binds and antagonizes RASSF6 tumor suppressor to suppress p53 expression.Domain analysis of Ras-association domain family member 6 upon interaction with MDM2.MYCN is recruited to the RASSF1A promoter but is not critical for DNA hypermethylation in neuroblastoma.Decreased expression and frequent promoter hypermethylation of RASSF2 and RASSF6 correlate with malignant progression and poor prognosis of gastric cardia adenocarcinoma.DNA methylation is a common molecular alteration in colorectal cancer cells and culture method has no influence on DNA methylation.E4BP4/NFIL3 modulates the epigenetically repressed RAS effector RASSF8 function through histone methyltransferases.Methylation of DNA and chromatin as a mechanism of oncogenesis and therapeutic target in neuroblastoma.The RASSF6 Tumor Suppressor Protein Regulates Apoptosis and Cell Cycle Progression via Retinoblastoma Protein
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P2860
The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
The RASSF gene family members ...... methylation in neuroblastoma.
@ast
The RASSF gene family members ...... methylation in neuroblastoma.
@en
type
label
The RASSF gene family members ...... methylation in neuroblastoma.
@ast
The RASSF gene family members ...... methylation in neuroblastoma.
@en
prefLabel
The RASSF gene family members ...... methylation in neuroblastoma.
@ast
The RASSF gene family members ...... methylation in neuroblastoma.
@en
P2860
P50
P356
P1433
P1476
The RASSF gene family members ...... methylation in neuroblastoma.
@en
P2093
P2860
P2888
P356
10.1186/1476-4598-11-40
P577
2012-06-13T00:00:00Z
P5875
P6179
1034976714