Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation
about
Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductaseDefining human ERAD networks through an integrative mapping strategyBifunctional apoptosis regulator (BAR), an endoplasmic reticulum (ER)-associated E3 ubiquitin ligase, modulates BI-1 protein stability and function in ER StressCYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligasesThe TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ERAn endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5-trisphosphate receptorsRegulation of endoplasmic reticulum-associated degradation by RNF5-dependent ubiquitination of JNK-associated membrane protein (JAMP)RNF185 is a novel E3 ligase of endoplasmic reticulum-associated degradation (ERAD) that targets cystic fibrosis transmembrane conductance regulator (CFTR)Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERADHRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradationDiversity of degradation signals in the ubiquitin-proteasome systemOne step at a time: endoplasmic reticulum-associated degradationE2 enzymes: more than just middle menEndoplasmic reticulum-mediated protein quality control in ArabidopsisUbiquitin on the move: the ubiquitin modification system plays diverse roles in the regulation of endoplasmic reticulum- and plasma membrane-localized proteinsRING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitinationRoad to ruin: targeting proteins for degradation in the endoplasmic reticulumAllosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78Solution structure and dynamics of human ubiquitin conjugating enzyme Ube2g2Ume6p is required for germination and early colony development of yeast ascospores.A systematic search for endoplasmic reticulum (ER) membrane-associated RING finger proteins identifies Nixin/ZNRF4 as a regulator of calnexin stability and ER homeostasisThe ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory groupUbiquitin-dependent proteasomal degradation of human liver cytochrome P450 2E1: identification of sites targeted for phosphorylation and ubiquitinationDystonia-associated mutations cause premature degradation of torsinA protein and cell-type-specific mislocalization to the nuclear envelopeTMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I.Increased endoplasmic reticulum stress and decreased proteasomal function in lafora disease models lacking the phosphatase laforinHuntingtin interacts with the cue domain of gp78 and inhibits gp78 binding to ubiquitin and p97/VCP.Ubiquitin ligase SYVN1/HRD1 facilitates degradation of the SERPINA1 Z variant/α-1-antitrypsin Z variant via SQSTM1/p62-dependent selective autophagy.Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates.Stringent requirement for HRD1, SEL1L, and OS-9/XTP3-B for disposal of ERAD-LS substrates.Cleavage by signal peptide peptidase is required for the degradation of selected tail-anchored proteins.Comparative sequence analysis reveals regulation of genes in developing schistosomula of Schistosoma mansoni exposed to host portal serumUbe2g2-gp78-mediated HERP polyubiquitylation is involved in ER stress recoverySerine residues in the cytosolic tail of the T-cell antigen receptor alpha-chain mediate ubiquitination and endoplasmic reticulum-associated degradation of the unassembled protein.The laforin-malin complex, involved in Lafora disease, promotes the incorporation of K63-linked ubiquitin chains into AMP-activated protein kinase beta subunits.Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductaseUbc4 and Not4 regulate steady-state levels of DNA polymerase-α to promote efficient and accurate DNA replication.Liver cytochrome P450 3A ubiquitination in vivo by gp78/autocrine motility factor receptor and C terminus of Hsp70-interacting protein (CHIP) E3 ubiquitin ligases: physiological and pharmacological relevance.Deglycosylation-dependent fluorescent proteins provide unique tools for the study of ER-associated degradation.ATL9, a RING zinc finger protein with E3 ubiquitin ligase activity implicated in chitin- and NADPH oxidase-mediated defense responses
P2860
Q24293757-6EC72137-2E08-47C7-AE86-AD0441E4C533Q24298439-B7F6409F-9C8F-4CC6-89F7-9286AFD303FCQ24306658-4CBEC1D0-79ED-4130-91B8-F850B6C83364Q24310116-1FEC2E1B-BE72-444E-9A9B-2E7AAB38015DQ24311488-FFA2C14D-5B88-4C9F-B222-E3038C316647Q24314540-85EF9C6C-1249-4CCD-8B0E-0FCE0753A193Q24318769-4F898212-D4CD-4317-85CE-097CEE5389E8Q24323658-EDC02409-4F78-4414-B411-CEB77D88EBFDQ24324707-E2C20655-8E1A-41E7-96E9-F41086890CD9Q24337606-FF73E96D-946D-45C6-B90F-695A93881E5FQ24642979-D134036E-01F1-4D04-8C37-1C0F2A4B96FBQ24658302-7733E4C9-BFBE-4E96-A64C-F3336C375FD6Q26752818-E84C0150-FA93-4C84-9353-7C9A2171F593Q26824018-A325AF2E-6F95-48B0-BFD6-4C77B1346542Q26849500-680E3833-1A7E-4D07-BF2E-259F904EB2D9Q26850008-4B42443F-497D-415B-8A82-2006D018A610Q26866096-5CAA8BC0-C4DF-4027-9083-15BC219609CFQ27646351-D5EC673A-FD7C-4608-8069-4080103631B3Q27658668-225F88ED-8517-463F-927C-91E86AAAF2D9Q27932692-FC2D6018-BA51-48C0-8F38-C67489A80502Q28114843-2693D9F4-35CC-46B1-A2E8-4FD0FF8AD50CQ28299691-9600E0A9-1327-4A93-B521-9E55C0A6DEDFQ28302541-ACA29F5E-B17B-473F-AABB-012886CC8219Q28386148-129998CB-639C-422C-B9BE-F572D06D406CQ29871423-3EF2B527-0174-4548-A59F-A71B087089BFQ33468448-119CDD7E-166D-47FE-884B-8768B0E0F594Q33529116-D9D45BCC-6A82-4C53-BE23-95BF320CC159Q33553536-C3BB65AF-1606-4973-A727-07FAB3538E91Q33590955-1E196C6F-646F-4EF8-9F9D-FDBC2F2EC83EQ33615098-0E0A23EE-3B78-4894-BB9E-7E6F5CA4F535Q33797023-4580EB5C-8CC2-460F-A260-63F6393AD15DQ33807012-02753C55-756A-4671-9CEA-8D9F11F8C239Q33817822-F60585F9-D960-4635-9639-EADB63E65C54Q34025425-2CD764FF-7186-4E13-8660-80D5B2F67A07Q34029315-86B0D7B2-AC3A-41AF-BDC5-2C16B5F3A827Q34119006-17AD20C1-CEE7-4E72-AFEE-86004DA9572EQ34123401-222F6211-E66F-44FB-930A-6AE7CF998D06Q34285339-DA5FB623-BE77-4F24-9DE3-08ACDB90345EQ34327353-0DFAC1E0-250E-4063-885F-465E8911B35EQ34437829-4417A444-10D4-4DE1-86D9-19C6D5BB6430
P2860
Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation
@ast
Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation
@en
type
label
Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation
@ast
Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation
@en
prefLabel
Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation
@ast
Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation
@en
P2860
P1476
Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation
@en
P2093
Allan M Weissman
Zlatka Kostova
P2860
P304
P356
10.1016/J.SEMCDB.2007.09.002
P577
2007-09-08T00:00:00Z