Small-molecule XIAP antagonist restores caspase-9 mediated apoptosis in XIAP-positive diffuse large B-cell lymphoma cells
about
XIAP is a predictor of cisplatin-based chemotherapy response and prognosis for patients with advanced head and neck cancerThe Smac mimetic RMT5265.2HCL induces apoptosis in EBV and HTLV-I associated lymphoma cells by inhibiting XIAP and promoting the mitochondrial release of cytochrome C and Smac.IAP-targeted therapies for cancer.Inhibitor of apoptosis proteins in hematological malignancies.Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part II: targeting cell cycle events, caspases, NF-κB and the proteasome.Non-Hodgkin's B-cell lymphoma: advances in molecular strategies targeting drug resistance.Essential role of TAK1 in regulating mantle cell lymphoma survival.Targeted alpha-therapy using [Bi-213]anti-CD20 as novel treatment option for radio- and chemoresistant non-Hodgkin lymphoma cells.Inhibitors of apoptosis: clinical implications in cancer.Downregulation of miR-374b-5p promotes chemotherapeutic resistance in pancreatic cancer by upregulating multiple anti-apoptotic proteins.
P2860
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P2860
Small-molecule XIAP antagonist restores caspase-9 mediated apoptosis in XIAP-positive diffuse large B-cell lymphoma cells
description
2007 nî lūn-bûn
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name
Small-molecule XIAP antagonist ...... se large B-cell lymphoma cells
@ast
Small-molecule XIAP antagonist ...... se large B-cell lymphoma cells
@en
type
label
Small-molecule XIAP antagonist ...... se large B-cell lymphoma cells
@ast
Small-molecule XIAP antagonist ...... se large B-cell lymphoma cells
@en
prefLabel
Small-molecule XIAP antagonist ...... se large B-cell lymphoma cells
@ast
Small-molecule XIAP antagonist ...... se large B-cell lymphoma cells
@en
P2093
P2860
P1433
P1476
Small-molecule XIAP antagonist ...... se large B-cell lymphoma cells
@en
P2093
Chris J L M Meijer
Clemencia Pinilla
Corine J Hess
Erik Hooijberg
Gert J Ossenkoppele
John C Reed
Joost J Oudejans
José Deurhof
Kate Welsh
Kitty C M Castricum
P2860
P304
P356
10.1182/BLOOD-2007-04-085480
P407
P577
2007-10-04T00:00:00Z