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Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosisRIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosisHistone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIPXIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signalingCellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcriptionIdentification of a novel anti-apoptotic E3 ubiquitin ligase that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC, HtrA2, and ARTSInteraction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosisSurvivin: a unique target for tumor therapyThe Modulation of Apoptotic Pathways by GammaherpesvirusesApoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategiesPotential of apoptotic pathway-targeted cancer therapeutic research: Where do we stand?Could the eIF2α-Independent Translation Be the Achilles Heel of Cancer?Targeting Apoptosis and Multiple Signaling Pathways with Icariside II in Cancer CellsInhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammationElucidation of the binding preferences of peptide recognition modules: SH3 and PDZ domainsMinnelide: a novel therapeutic that promotes apoptosis in non-small cell lung carcinoma in vivoCrystal Structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 Complexes: Affinity, Specificity, and RegulationSmac modulates chemosensitivity in head and neck cancer cells through the mitochondrial apoptotic pathwayMechanism of the interaction between the intrinsically disordered C-terminus of the pro-apoptotic ARTS protein and the Bir3 domain of XIAPA small molecule SMAC mimic LBW242 potentiates TRAIL- and anticancer drug-mediated cell death of ovarian cancer cellsAlterations in Red Blood Cell Functionality Induced by an Indole Scaffold Containing a Y-Iminodiketo Moiety: Potential Antiproliferative ConditionsThe death effector domains of caspase-8 induce terminal differentiation.The role of HTS in drug discovery at the University of Michigan.PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.Inhibitors of apoptosis proteins (IAPs) expression and their prognostic significance in hepatocellular carcinoma.Cellular stress responses: cell survival and cell deathApoptotic death of cancer stem cells for cancer therapy.Action of YM155 on clear cell renal cell carcinoma does not depend on survivin expression levelsOvercoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)Survivin as a potential mediator to support autoreactive cell survival in myasthenia gravis: a human and animal model studySMAC mimetic BV6 induces cell death in monocytes and maturation of monocyte-derived dendritic cells.BV6, an IAP antagonist, activates apoptosis and enhances radiosensitization of non-small cell lung carcinoma in vitroMultiple mechanisms modulate distinct cellular susceptibilities toward apoptosis in the developing Drosophila eye.Purine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: a tangible union against chemoresistant cancerDifferential effects of whole soy extract and soy isoflavones on apoptosis in prostate cancer cellsCell deathPaeonol inhibits tumor growth in gastric cancer in vitro and in vivo.Inhibitor of Apoptosis (IAP) proteins as drug targets for the treatment of cancerXIAP is a predictor of cisplatin-based chemotherapy response and prognosis for patients with advanced head and neck cancerHost insect inhibitor-of-apoptosis SfIAP functionally replaces baculovirus IAP but is differentially regulated by Its N-terminal leader.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
IAP-targeted therapies for cancer.
@en
IAP-targeted therapies for cancer.
@nl
type
label
IAP-targeted therapies for cancer.
@en
IAP-targeted therapies for cancer.
@nl
prefLabel
IAP-targeted therapies for cancer.
@en
IAP-targeted therapies for cancer.
@nl
P2093
P2860
P356
P1433
P1476
IAP-targeted therapies for cancer.
@en
P2093
D J Mahoney
E C LaCasse
H H Cheung
R G Korneluk
S Plenchette
P2860
P2888
P304
P356
10.1038/ONC.2008.302
P407
P577
2008-10-01T00:00:00Z