about
Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinasesRSK3: A regulator of pathological cardiac remodelingComputational and Biochemical Discovery of RSK2 as a Novel Target for Epigallocatechin Gallate (EGCG)Kaposi's sarcoma-associated herpesvirus ORF45 mediates transcriptional activation of the HIV-1 long terminal repeat via RSK2.Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism.RNA interference screening identifies lenalidomide sensitizers in multiple myeloma, including RSK2.Phosphoproteomic analysis reveals an intrinsic pathway for the regulation of histone deacetylase 7 that controls the function of cytotoxic T lymphocytes.p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.DGCR14 induces Il17a gene expression through the RORγ/BAZ1B/RSKS2 complex.Regulation of NHE3 by lysophosphatidic acid is mediated by phosphorylation of NHE3 by RSK2.The PDK1-Rsk Signaling Pathway Controls Langerhans Cell Proliferation and Patterning.Identification of germ cell-specific genes in mammalian meiotic prophase.RSK3 is required for concentric myocyte hypertrophy in an activated Raf1 model for Noonan syndrome.RSK2 activity mediates glioblastoma invasiveness and is a potential target for new therapeutics.Serine-threonine kinases in TCR signaling.Ribosomal S6 kinase (RSK) modulators: a patent review.The use of growth factors to modulate the activities of antigen-specific CD8+ T cells in vitro.Fibroblast growth factor receptor 3 associates with and tyrosine phosphorylates p90 RSK2, leading to RSK2 activation that mediates hematopoietic transformation.RSK2 phosphorylates T-bet to attenuate colon cancer metastasis and growth.The promise and challenges of targeting RSK for the treatment of cancer.Kaempferol targeting on the fibroblast growth factor receptor 3-ribosomal S6 kinase 2 signaling axis prevents the development of rheumatoid arthritis.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Critical role for Rsk2 in T-lymphocyte activation
@ast
Critical role for Rsk2 in T-lymphocyte activation
@en
type
label
Critical role for Rsk2 in T-lymphocyte activation
@ast
Critical role for Rsk2 in T-lymphocyte activation
@en
prefLabel
Critical role for Rsk2 in T-lymphocyte activation
@ast
Critical role for Rsk2 in T-lymphocyte activation
@en
P2093
P2860
P1433
P1476
Critical role for Rsk2 in T-lymphocyte activation
@en
P2093
Jian-Xin Lin
Rosanne Spolski
Warren J Leonard
P2860
P304
P356
10.1182/BLOOD-2007-02-072207
P407
P577
2007-10-15T00:00:00Z