The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.

The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.

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http://www.wikidata.org/entity/Q36385532
An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function.Practical considerations for choosing a mouse model of Alzheimer's disease.Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy.Microglia at center stage: a comprehensive review about the versatile and unique residential macrophages of the central nervous system.Microglia emerge as central players in brain disease.OH MYeloid! Immune cells wreaking havoc on brain homeostasis.Immunity at the forefront of the brain: A new genetic model of FTD.TREM2 regulates innate immunity in Alzheimer's disease.Functional Studies of Missense TREM2 Mutations in Human Stem Cell-Derived Microglia.Highly efficient RNA-guided base editing in rabbit.Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroupWhite matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's diseaseThe Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humansEarly lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout miceOrthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes
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The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.

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http://www.wikidata.org/entity/Q36385532
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The FTD-like syndrome causing ...... usion, and glucose metabolism.
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The FTD-like syndrome causing ...... usion, and glucose metabolism.
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The FTD-like syndrome causing ...... usion, and glucose metabolism.
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