Physiological role of ROCKs in the cardiovascular system - Wikidata - awgldk - TriplyDB

Physiological role of ROCKs in the cardiovascular system

Physiological role of ROCKs in the cardiovascular system

http://www.wikidata.org/entity/Q36392528

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Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation Selective ROCK2 inhibition in focal cerebral ischemia Brain endothelial cell-cell junctions: how to "open" the blood brain barrier Calcium Sensitization Mechanisms in Gastrointestinal Smooth Muscles Contractile apparatus dysfunction early in the pathophysiology of diabetic cardiomyopathy Targeting G protein coupled receptor-related pathways as emerging molecular therapies ROCKs as immunomodulators of stroke The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication Anaplasma phagocytophilum specifically induces tyrosine phosphorylation of ROCK1 during infection Aging and the control of human skin blood flow Characterization of dysferlin deficient SJL/J mice to assess preclinical drug efficacy: fasudil exacerbates muscle disease phenotype RhoA regulates peroxisome association to microtubules and the actin cytoskeleton Focal adhesion kinase as a RhoA-activable signaling scaffold mediating Akt activation and cardiomyocyte protection Kalirin promotes neointimal hyperplasia by activating Rac in smooth muscle cells Little ROCK is a ROCK1 pseudogene expressed in human smooth muscle cells The Rho kinase Rock2b establishes anteroposterior asymmetry of the ciliated Kupffer's vesicle in zebrafish.Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms Extraction of membrane cholesterol disrupts caveolae and impairs serotonergic (5-HT2A) and histaminergic (H1) responses in bovine airway smooth muscle: role of Rho-kinase.Reflex vasoconstriction in aged human skin increasingly relies on Rho kinase-dependent mechanisms during whole body cooling Experimental benefits of sex hormones on vascular function and the outcome of hormone therapy in cardiovascular disease.Cadherin-11 regulates both mesenchymal stem cell differentiation into smooth muscle cells and the development of contractile function in vivo Gene variations of ROCKs and risk of ischaemic stroke: the Women's Genome Health Study.Divergent roles of nitric oxide and rho kinase in vasomotor regulation of human retinal arterioles Association of moderate aerobic exercise and rho-associated kinase 2 concentration in subjects with dyslipidemia Rho kinase proteins display aberrant upregulation in vascular tumors and contribute to vascular tumor growth.Synergistic effects of matrix nanotopography and stiffness on vascular smooth muscle cell function.Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.ROCK1 plays an essential role in the transition from cardiac hypertrophy to failure in mice.Urotensin II alters vascular reactivity in animals subjected to volume overload.MicroRNA-494 targeting both proapoptotic and antiapoptotic proteins protects against ischemia/reperfusion-induced cardiac injury Estrogen receptor-beta prevents cardiac fibrosis.Regulation of GPCR signaling in hypertension.Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis.Levels and values of lipoprotein-associated phospholipase A2, galectin-3, RhoA/ROCK, and endothelial progenitor cells in critical limb ischemia: pharmaco-therapeutic role of cilostazol and clopidogrel combination therapy.Association analysis of polymorphisms in ROCK2 with cardiovascular disease in a Chinese population.TGF-β2 reduces nitric oxide synthase mRNA through a ROCK-dependent pathway in airway epithelial cells.The endothelium: influencing vascular smooth muscle in many ways.Tie1 attenuation reduces murine atherosclerosis in a dose-dependent and shear stress-specific manner

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P2860

Physiological role of ROCKs in the cardiovascular system

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Physiological role of ROCKs in the cardiovascular system

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James K Liao

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P2860

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop

Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase

Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis

NOSIP, a novel modulator of endothelial nitric oxide synthase activity

Rocks: multifunctional kinases in cell behaviour

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton

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