Structure-activity relationships among the kanamycin aminoglycosides: role of ring I hydroxyl and amino groups
about
Dual Targeting of Intracellular Pathogenic Bacteria with a Cleavable Conjugate of Kanamycin and an Antibacterial Cell-Penetrating Peptide.Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression.In vitro and in vivo Evaluation of Synergism between Anti-Tubercular Spectinamides and Non-Classical Tuberculosis AntibioticsAminomethyl spectinomycins as therapeutics for drug-resistant respiratory tract and sexually transmitted bacterial infectionsMutational activation of the AmgRS two-component system in aminoglycoside-resistant Pseudomonas aeruginosa.Proposing a mechanism of action for ataluren.Prospects for circumventing aminoglycoside kinase mediated antibiotic resistance.Detection and Quantification of Ribosome Inhibition by Aminoglycoside Antibiotics in Living Bacteria Using an Orthogonal Ribosome-Controlled Fluorescent ReporterAntibiotics Resistance in Rhizobium: Type, Process, Mechanism and Benefit for Agriculture.N6', N6''', and O4' Modifications to Neomycin Affect Ribosomal Selectivity without Compromising Antibacterial Activity.Tobramycin Variants with Enhanced Ribosome-Targeting ActivityAtomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.Selective modification of the 3''-amino group of kanamycin prevents significant loss of activity in resistant bacterial strains.Advances in therapeutic use of a drug-stimulated translational readthrough of premature termination codons.
P2860
Q33828350-D0121833-66C5-4EFC-9AD6-1E98BC898FB8Q34541951-BAA86C8A-FBCE-400A-A86A-3C39454AF88CQ36056408-FE367ED7-1DAA-42E6-AFC0-8BE88AA20FD9Q36270721-8BC84E2C-9BAB-4795-9428-C6AB452C2B84Q36785893-07087C3D-5F55-4858-87D5-9A1B01454E2FQ37398231-75E7C3D5-D39D-4BED-8666-1F1608E369D8Q38117380-30444179-65BC-435F-9853-A5AECBC4BC3BQ38618292-EF3038D9-20DA-4C0A-89F7-74F79F7AC768Q38741995-EBC32154-E95B-4BF1-AA90-469AB691B650Q40278411-41882B25-0D75-4C7D-9937-A52017AE85BEQ42138277-B8989907-2894-4F44-8BA7-91CB8A383DB5Q43794835-6E639F4D-D7F5-49B4-8782-624B000D73D7Q53811918-3E4D5669-EA80-4C85-8A7F-C816EBA6084BQ55497000-E83CCC87-439B-4A75-8B7C-099EE3EF17A5
P2860
Structure-activity relationships among the kanamycin aminoglycosides: role of ring I hydroxyl and amino groups
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Structure-activity relationshi ...... ng I hydroxyl and amino groups
@ast
Structure-activity relationshi ...... ng I hydroxyl and amino groups
@en
type
label
Structure-activity relationshi ...... ng I hydroxyl and amino groups
@ast
Structure-activity relationshi ...... ng I hydroxyl and amino groups
@en
prefLabel
Structure-activity relationshi ...... ng I hydroxyl and amino groups
@ast
Structure-activity relationshi ...... ng I hydroxyl and amino groups
@en
P2093
P2860
P356
P1476
Structure-activity relationshi ...... ng I hydroxyl and amino groups
@en
P2093
Andrea Vasella
Bruno B Bernet
Dmitri Shcherbakov
Eric Westhof
Martin Meyer
Rashid Akbergenov
Shinde Harish
Stefan Duscha
Sumantha Salian
Tanja Matt
P2860
P304
P356
10.1128/AAC.01326-12
P407
P577
2012-09-04T00:00:00Z