Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding.
about
Identification of verrucarin a as a potent and selective steroid receptor coactivator-3 small molecule inhibitorAutoactivation of the MDM2 E3 ligase by intramolecular interaction.Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS.Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.Autoinhibition of MDMX by intramolecular p53 mimicrySecondary interaction between MDMX and p53 core domain inhibits p53 DNA binding.MDMX contains an autoinhibitory sequence element.Biological functions of casein kinase 1 isoforms and putative roles in tumorigenesis.MDMX (MDM4), a Promising Target for p53 Reactivation Therapy and Beyond.Let-7b expression determines response to chemotherapy through the regulation of cyclin D1 in glioblastomaNetwork-based identification of key proteins involved in apoptosis and cell cycle regulation.Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.The fate of murine double minute X (MdmX) is dictated by distinct signaling pathways through murine double minute 2 (Mdm2).Casein kinase 1α: biological mechanisms and theranostic potential.
P2860
Q28538014-30B0F8C3-DC2E-4882-8FDA-1A1B20E94BAEQ34056449-9E8627CB-76C8-4183-93B5-DA0176E3F482Q34348631-AD2ED552-1A1C-438A-9879-4B5E5605D7FAQ34483086-BD35D209-EF2A-4985-B5F6-F517FD4171D4Q35485193-08DBE429-78E1-4ABC-8C3C-3D43426731BEQ36905080-1CF30914-1AC8-4233-8107-D165C4131176Q37276522-919F8DF6-493A-4A8C-B515-E1FF0547B122Q38259229-39067983-9EE3-4192-8B82-EE94F06AA6F3Q38884006-A8B2EF4F-7D92-4D62-A62B-1144724ECFB0Q39134240-2B913D05-F5E2-447A-AC71-440EA9E6833EQ39181880-823A94A5-6B08-4A95-A851-033B6D36BCE0Q41378204-97C7FB70-52AD-4427-9282-A8873B559E55Q47116674-436A00B2-315E-4407-AC63-1196BFB02B0BQ54940982-BCCE52A4-EC9C-4B73-A188-A85E2D7B4A74
P2860
Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding.
@ast
Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding.
@en
type
label
Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding.
@ast
Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding.
@en
prefLabel
Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding.
@ast
Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding.
@en
P2093
P2860
P356
P1476
Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding.
@en
P2093
Andreas Becker
Ernst Schonbrunn
Jiandong Chen
Lihong Chen
Shaofang Wu
P2860
P304
P356
10.1128/MCB.00851-12
P407
P577
2012-10-01T00:00:00Z