Molecular model of the outward facing state of the human P-glycoprotein (ABCB1), and comparison to a model of the human MRP5 (ABCC5)
about
Localization of putative binding sites for cyclic guanosine monophosphate and the anti-cancer drug 5-fluoro-2'-deoxyuridine-5'-monophosphate on ABCC11 in silico modelsEquilibrated atomic models of outward-facing P-glycoprotein and effect of ATP binding on structural dynamics.Molecular models of human P-glycoprotein in two different catalytic statesData-driven homology modelling of P-glycoprotein in the ATP-bound state indicates flexibility of the transmembrane domains.Hyaluronan export through plasma membranes depends on concurrent K+ efflux by K(ir) channels.Toward understanding the mechanism of action of the yeast multidrug resistance transporter Pdr5p: a molecular modeling study.The molecular and physiological roles of ABCC6: more than meets the eye.On the origin of large flexibility of P-glycoprotein in the inward-facing stateHuman P-glycoprotein contains a greasy ball-and-socket joint at the second transmission interface.Binding site of ABC transporter homology models confirmed by ABCB1 crystal structureMultidrug efflux pumps: the structures of prokaryotic ATP-binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P-glycoproteins and homologues.Multidrug efflux pumps: drug binding--gates or cavity?Drug transport by breast cancer resistance protein.Impact of the Recent Mouse P-Glycoprotein Structure for Structure-Based Ligand Design.Homology modeling and binding site assessment of the human P-glycoprotein.Novel cGMP efflux inhibitors identified by virtual ligand screening (VLS) and confirmed by experimental studies.Locking intracellular helices 2 and 3 together inactivates human P-glycoprotein.The human transporter associated with antigen processing: molecular models to describe peptide binding competent states.Recognition of sulfonylurea receptor (ABCC8/9) ligands by the multidrug resistance transporter P-glycoprotein (ABCB1): functional similarities based on common structural features between two multispecific ABC proteins.
P2860
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P2860
Molecular model of the outward facing state of the human P-glycoprotein (ABCB1), and comparison to a model of the human MRP5 (ABCC5)
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Molecular model of the outward ...... odel of the human MRP5 (ABCC5)
@ast
Molecular model of the outward ...... odel of the human MRP5 (ABCC5)
@en
type
label
Molecular model of the outward ...... odel of the human MRP5 (ABCC5)
@ast
Molecular model of the outward ...... odel of the human MRP5 (ABCC5)
@en
prefLabel
Molecular model of the outward ...... odel of the human MRP5 (ABCC5)
@ast
Molecular model of the outward ...... odel of the human MRP5 (ABCC5)
@en
P2860
P356
P1476
Molecular model of the outward ...... odel of the human MRP5 (ABCC5)
@en
P2093
Aina W Ravna
Georg Sager
P2860
P2888
P356
10.1186/1742-4682-4-33
P577
2007-09-06T00:00:00Z
P5875
P6179
1045567051