Age-resolving osteopetrosis: a rat model implicating microphthalmia and the related transcription factor TFE3.
about
Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development.Regulation of the MiTF/TFE bHLH-LZ transcription factors through restricted spatial expression and alternative splicing of functional domainsTranscription factor MITF regulates cardiac growth and hypertrophySuppression of microphthalmia transcriptional activity by its association with protein kinase C-interacting protein 1 in mast cellsThe regulation of cathepsin K gene expressionVMD2 promoter requires two proximal E-box sites for its activity in vivo and is regulated by the MITF-TFE familyRenal carcinoma-associated transcription factors TFE3 and TFEB are leukemia inhibitory factor-responsive transcription activators of E-cadherinBiallelic Mutations in MITF Cause Coloboma, Osteopetrosis, Microphthalmia, Macrocephaly, Albinism, and DeafnessRole played by microphthalmia transcription factor phosphorylation and its Zip domain in its transcriptional inhibition by PIAS3Commitment and differentiation of stem cells to the osteoclast lineage.Mitf induction by RANKL is critical for osteoclastogenesis.A novel isoform of microphthalmia-associated transcription factor inhibits IL-8 gene expression in human cervical stromal cellsThe discovery of the microphthalmia locus and its gene, Mitf.Linking osteopetrosis and pycnodysostosis: regulation of cathepsin K expression by the microphthalmia transcription factor familyMicrophthalamia-associated transcription factor: a critical regulator of pigment cell development and survival.c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi.The generation and characterization of a cell line derived from a sporadic renal angiomyolipoma: use of telomerase to obtain stable populations of cells from benign neoplasmsMicrophthalmia transcription factor. A sensitive and specific melanocyte marker for MelanomaDiagnosis.Isolation of mouse stromal cells associated with a human tumor using differential diphtheria toxin sensitivityWhen developmental biology meets human pathologyTranscription Factor Tfe3 Directly Regulates Pgc-1alpha in MuscleMicrophthalmia gene product as a signal transducer in cAMP-induced differentiation of melanocytes.Failure to Target RANKL Signaling Through p38-MAPK Results in Defective Osteoclastogenesis in the Microphthalmia Cloudy-Eyed Mutant.Pharmacologic suppression of MITF expression via HDAC inhibitors in the melanocyte lineageRefined genomic localization of the genetic lesion in the osteopetrosis (op) rat and exclusion of three positional and functional candidate genes, Clcn7, Atp6v0c, and Slc9a3r2.Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.Comparative transcriptome analysis of molecular mechanism underlying gray-to-red body color formation in red crucian carp (Carassius auratus, red var.).Embryonic expression of zebrafish MiT family genes tfe3b, tfeb, and tfec.Interplay between MITF, PIAS3, and STAT3 in mast cells and melanocytes.The identification and functional characterization of a novel mast cell isoform of the microphthalmia-associated transcription factor.Hypoxia-inducible factor 1{alpha} is a new target of microphthalmia-associated transcription factor (MITF) in melanoma cells.Genetic and physical interactions between Microphthalmia transcription factor and PU.1 are necessary for osteoclast gene expression and differentiation.Microphthalmia-associated transcription factor (MITF) is required but is not sufficient to induce the expression of melanogenic genes.Involvement of microphthalmia in the inhibition of melanocyte lineage differentiation and of melanogenesis by agouti signal protein.
P2860
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P2860
Age-resolving osteopetrosis: a rat model implicating microphthalmia and the related transcription factor TFE3.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Age-resolving osteopetrosis: a ...... ted transcription factor TFE3.
@ast
Age-resolving osteopetrosis: a ...... ted transcription factor TFE3.
@en
type
label
Age-resolving osteopetrosis: a ...... ted transcription factor TFE3.
@ast
Age-resolving osteopetrosis: a ...... ted transcription factor TFE3.
@en
prefLabel
Age-resolving osteopetrosis: a ...... ted transcription factor TFE3.
@ast
Age-resolving osteopetrosis: a ...... ted transcription factor TFE3.
@en
P2093
P2860
P356
P1476
Age-resolving osteopetrosis: a ...... ted transcription factor TFE3.
@en
P2093
A H Tashjian
C L Hershey
C M Takemoto
D E Fisher
K N Weilbaecher
M A Horstmann
T J Hemesath
P2860
P304
P356
10.1084/JEM.187.5.775
P407
P577
1998-03-01T00:00:00Z