CD4+ T cell tolerance to parenchymal self-antigens requires presentation by bone marrow-derived antigen-presenting cells
about
The induction of tolerance by dendritic cells that have captured apoptotic cellsAnergy and cytokine-mediated suppression as distinct superantigen-induced tolerance mechanisms in vivoSub-lethal radiation enhances anti-tumor immunotherapy in a transgenic mouse model of pancreatic cancerCell death in the maintenance and abrogation of tolerance: the five Ws of dying cellsDendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivoRegulation of T-cell Tolerance by Lymphatic Endothelial Cells.CD30 prevents T-cell responses to non-lymphoid tissues.Peripheral T-cell tolerance: the contribution of permissive T-cell migration into parenchymal tissues of the neonate.In vivo cyclophosphamide and IL-2 treatment impedes self-antigen-induced effector CD4 cell tolerization: implications for adoptive immunotherapy.Effector CD4 cell tolerization is mediated through functional inactivation and involves preferential impairment of TNF-alpha and IFN-gamma expression potentials.Steady state dendritic cells present parenchymal self-antigen and contribute to, but are not essential for, tolerization of naive and Th1 effector CD4 cells.Dendritic cells program non-immunogenic prostate-specific T cell responses beginning at early stages of prostate tumorigenesis.Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen.T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-gamma expression.Effector CD4 cells are tolerized upon exposure to parenchymal self-antigen.Histone acetylation at the Ifng promoter in tolerized CD4 cells is associated with increased IFN-gamma expression during subsequent immunization to the same antigenPeripheral Tolerization of Effector and Memory T Cells: Implications for Autoimmunity and Tumor-Immunity.The E3 ubiquitin ligase Cbl-b regulates expansion but not functional activity of self-reactive CD4 T cellsHuman papillomavirus type 16 E7 oncoprotein expressed in peripheral epithelium tolerizes E7-directed cytotoxic T-lymphocyte precursors restricted through human (and mouse) major histocompatibility complex class I allelesIntracellular MHC class II controls regulatory tolerance to allogeneic transplants.Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance.CD8(+) but not CD8(-) dendritic cells cross-prime cytotoxic T cells in vivo.Remnants of suicidal cells fostering systemic autoaggression. Apoptosis in the origin and maintenance of autoimmunity.Apoptotic cell-based therapies against transplant rejection: role of recipient's dendritic cells.Developing antigen-specific therapies in multiple sclerosis: a tale of Tantalus or Ulysses?Peripheral T-cell tolerance defined through transgenic mouse studies.Dendritic cells and immunotherapy for malignant disease.Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escapeThe enemy within: keeping self-reactive T cells at bay in the periphery.Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cellsGM-CSF gene-modifed cancer cell immunotherapies: of mice and men.Antigen-presenting cells and tolerance induction.LAG-3 regulates CD8+ T cell accumulation and effector function in murine self- and tumor-tolerance systems.Efferocytosis promotes suppressive effects on dendritic cells through prostaglandin E2 production in the context of autoimmunity.FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer.The role of dendritic cell subsets in selection between tolerance and immunity.Tumor recognition and self-recognition induce distinct transcriptional profiles in antigen-specific CD4 T cells.Tc17 CD8 T cells: functional plasticity and subset diversity.Functionally distinct LAG-3 and PD-1 subsets on activated and chronically stimulated CD8 T cellsDendritic cells under investigation in autoimmune disease.
P2860
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P2860
CD4+ T cell tolerance to parenchymal self-antigens requires presentation by bone marrow-derived antigen-presenting cells
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
CD4+ T cell tolerance to paren ...... rived antigen-presenting cells
@ast
CD4+ T cell tolerance to paren ...... rived antigen-presenting cells
@en
type
label
CD4+ T cell tolerance to paren ...... rived antigen-presenting cells
@ast
CD4+ T cell tolerance to paren ...... rived antigen-presenting cells
@en
prefLabel
CD4+ T cell tolerance to paren ...... rived antigen-presenting cells
@ast
CD4+ T cell tolerance to paren ...... rived antigen-presenting cells
@en
P2093
P2860
P356
P1476
CD4+ T cell tolerance to paren ...... rived antigen-presenting cells
@en
P2093
D M Pardoll
G S Yochum
W G Nelson
P2860
P304
P356
10.1084/JEM.187.10.1555
P407
P577
1998-05-01T00:00:00Z