Lysophosphatidic acid induces neointima formation through PPARgamma activation.
about
PPARs and the cardiovascular systemA novel acylglycerol kinase that produces lysophosphatidic acid modulates cross talk with EGFR in prostate cancer cellsLysophosphatidic acid activates peroxisome proliferator activated receptor-γ in CHO cells that over-express glycerol 3-phosphate acyltransferase-1alpha- and beta-substituted phosphonate analogs of LPA as autotaxin inhibitorsLysophosphatidic acid receptors 1 and 2 play roles in regulation of vascular injury responses but not blood pressure.Nitrolinoleic acid: an endogenous peroxisome proliferator-activated receptor gamma ligandPhosphatidate degradation: phosphatidate phosphatases (lipins) and lipid phosphate phosphatases.Atherosclerotic lesion progression changes lysophosphatidic acid homeostasis to favor its accumulation.Lysophosphatidic acid in atherosclerotic diseasesAiming drug discovery at lysophosphatidic acid targets.Lysophosphatidic acid-operated K+ channels.US28 is a potent activator of phospholipase C during HCMV infection of clinically relevant target cellsLysophosphatidic acid suppresses endothelial cell CD36 expression and promotes angiogenesis via a PKD-1-dependent signaling pathway.Vascular involvement in systemic sclerosis (scleroderma).Lysophosphatidic acid signaling protects pulmonary vasculature from hypoxia-induced remodeling.Pathogenesis of Systemic Sclerosis.Lpa2 is a negative regulator of both dendritic cell activation and murine models of allergic lung inflammation.Lysophosphatidic acid causes endothelial dysfunction in porcine coronary arteries and human coronary artery endothelial cells.Phospholipase D2-dependent inhibition of the nuclear hormone receptor PPARgamma by cyclic phosphatidic acid.The early- and late stages in phenotypic modulation of vascular smooth muscle cells: differential roles for lysophosphatidic acidPPAR γ Networks in Cell Signaling: Update and Impact of Cyclic Phosphatidic Acid.Identification of non-lipid LPA3 antagonists by virtual screening.PPARs and their metabolic modulation: new mechanisms for transcriptional regulation?Lysophospholipid interactions with protein targets.Roles of lysophosphatidic acid in cardiovascular physiology and diseaseRegulation of the LPA2 receptor signaling through the carboxyl-terminal tail-mediated protein-protein interactionsTherapeutic potential of autotaxin/lysophospholipase d inhibitors.Sphingosine kinase is induced in mouse 3T3-L1 cells and promotes adipogenesisLysophosphatidic acid signaling in airway epithelium: role in airway inflammation and remodeling.Analyses of group III secreted phospholipase A2 transgenic mice reveal potential participation of this enzyme in plasma lipoprotein modification, macrophage foam cell formation, and atherosclerosis.Lipid phosphate phosphatases and signaling.Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cellsLysophosphatidic acid-induced arterial wall remodeling: requirement of PPARgamma but not LPA1 or LPA2 GPCR.Dominant-negative loss of PPARgamma function enhances smooth muscle cell proliferation, migration, and vascular remodeling.Emigration of monocyte-derived cells from atherosclerotic lesions characterizes regressive, but not progressive, plaques.The autotaxin-LPA axis emerges as a novel regulator of lymphocyte homing and inflammation.Regulation of blood and vascular cell function by bioactive lysophospholipids.The effects of aspirin and fish oil consumption on lysophosphatidylcholines and lysophosphatidic acids and their correlates with platelet aggregation in adults with diabetes mellitus.Arguing the case for the autotaxin-lysophosphatidic acid-lipid phosphate phosphatase 3-signaling nexus in the development and complications of atherosclerosis.Peroxisomes: a nexus for lipid metabolism and cellular signaling.
P2860
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P2860
Lysophosphatidic acid induces neointima formation through PPARgamma activation.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Lysophosphatidic acid induces neointima formation through PPARgamma activation.
@ast
Lysophosphatidic acid induces neointima formation through PPARgamma activation.
@en
type
label
Lysophosphatidic acid induces neointima formation through PPARgamma activation.
@ast
Lysophosphatidic acid induces neointima formation through PPARgamma activation.
@en
prefLabel
Lysophosphatidic acid induces neointima formation through PPARgamma activation.
@ast
Lysophosphatidic acid induces neointima formation through PPARgamma activation.
@en
P2093
P2860
P356
P1476
Lysophosphatidic acid induces neointima formation through PPARgamma activation
@en
P2093
Chunxiang Zhang
Daniel L Baker
Gabor Tigyi
Glenn D Prestwich
Gopal K Marathe
Hoe-Sup Byun
Leonard R Johnson
Louisa Balazs
Natalia Makarova
Robert Bittman
P2860
P304
P356
10.1084/JEM.20031619
P407
P577
2004-03-08T00:00:00Z