Impaired early B cell tolerance in patients with rheumatoid arthritis. - Wikidata - awgldk - TriplyDB

Impaired early B cell tolerance in patients with rheumatoid arthritis.

Impaired early B cell tolerance in patients with rheumatoid arthritis.

http://www.wikidata.org/entity/Q36402969

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Signalling of the BCR is regulated by a lipid rafts-localised transcription factor, Bright.IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans The gut-joint axis: cross reactive food antibodies in rheumatoid arthritis Resolve, revise, and relax: the 3 Rs of B cell repertoire adjustment Autoantibodies in systemic autoimmune diseases: specificity and pathogenicity Putting together the autoimmunity puzzle.Quantification of specific T and B cells immunological markers in children with chronic and transient ITP.B cells in rheumatoid arthritis: from pathogenic players to disease biomarkers.Antiviral immune responses: triggers of or triggered by autoimmunity?Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus.Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays.Expression of the inherently autoreactive idiotope 9G4 on autoantibodies to citrullinated peptides and on rheumatoid factors in patients with early and established rheumatoid arthritis.Central B-cell tolerance: where selection begins.Subversion of B lymphocyte tolerance by hydralazine, a potential mechanism for drug-induced lupus.Insights from populations at risk for the future development of classified rheumatoid arthritis Accumulation of self-reactive naïve and memory B cell reveals sequential defects in B cell tolerance checkpoints in Sjögren's syndrome.Distinct effects of methotrexate and etanercept on the B cell compartment in patients with juvenile idiopathic arthritis Drug free remission after steroid-dependent disappearance of lymphoproliferative disorder in rheumatoid arthritis patient treated with TNF-alpha blockade: case study.Harnessing the immune system's arsenal: producing human monoclonal antibodies for therapeutics and investigating immune responses.The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans B-cell pathology in juvenile idiopathic arthritis.Autoimmune host-microbiota interactions at barrier sites and beyond.High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination.B cells and autoimmunity.Autoreactivity in human IgG+ memory B cells.Expansion of autoreactive unresponsive CD21-/low B cells in Sjögren's syndrome-associated lymphoproliferation.The microRNA miR-148a functions as a critical regulator of B cell tolerance and autoimmunity.Autoantigen-specific B-cell depletion overcomes failed immune tolerance in type 1 diabetes Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID Balancing diversity and tolerance: lessons from patients with systemic lupus erythematosus.The Role of Latently Infected B Cells in CNS Autoimmunity.Persistent expression of autoantibodies in SLE patients in remission.Targeting Anti-Insulin B Cell Receptors Improves Receptor Editing in Type 1 Diabetes-Prone Mice.Dual-reactive B cells are autoreactive and highly enriched in the plasmablast and memory B cell subsets of autoimmune mice.Follicular B helper T cells in antibody responses and autoimmunity.Scientific rationale for extrapolation of biosimilar data across cancer indications: case study of CT-P10.Rituximab does not reset defective early B cell tolerance checkpoints Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation.Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning Analysis of IgM antibody production and repertoire in a mouse model of Sjögren's syndrome.

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P2860

Impaired early B cell tolerance in patients with rheumatoid arthritis.

http://www.wikidata.org/entity/Q36402969

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

Impaired early B cell tolerance in patients with rheumatoid arthritis.

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Impaired early B cell tolerance in patients with rheumatoid arthritis.

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type

label

Impaired early B cell tolerance in patients with rheumatoid arthritis.

@ast

Impaired early B cell tolerance in patients with rheumatoid arthritis.

@en

prefLabel

Impaired early B cell tolerance in patients with rheumatoid arthritis.

@ast

Impaired early B cell tolerance in patients with rheumatoid arthritis.

@en

P1433

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Journal of Experimental Medicine

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Impaired early B cell tolerance in patients with rheumatoid arthritis

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P2093

Claire Coupillaud

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Daniel Paget

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Eric Meffre

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Yen-Shing Ng

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P2860

Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies

The antiperinuclear factor and the so-called antikeratin antibodies are the same rheumatoid arthritis-specific autoantibodies

A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.

Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.

B-cell antigen receptor stimulation activates the human Bruton's tyrosine kinase, which is deficient in X-linked agammaglobulinemia

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

Predominant autoantibody production by early human B cell precursors

Rheumatoid factors isolated from patients with autoimmune disorders are derived from germline genes distinct from those encoding the Wa, Po, and Bla cross-reactive idiotypes.

Rituximab therapy and autoimmune disorders: prospects for anti-B cell therapy.

Most peripheral B cells in mice are ligand selected.

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1659-1667

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10

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201

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Jonathan Samuels

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2212916

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