Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma. - Wikidata - awgldk - TriplyDB

Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma.

Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma.

http://www.wikidata.org/entity/Q36403518

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SMAD3 deficiency promotes inflammatory aortic aneurysms in angiotensin II-infused mice via activation of iNOS Phosphoinositides: tiny lipids with giant impact on cell regulation PI3Kγ in hypertension: a novel therapeutic target controlling vascular myogenic tone and target organ damage PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation The Multifaceted Roles of PI3Kγ in Hypertension, Vascular Biology, and Inflammation Phosphatidylinositol-3-kinase p110γ contributes to bile salt-induced apoptosis in primary rat hepatocytes and human hepatoma cells Regulation of p110delta PI 3-kinase gene expression.Cytoglobin regulates blood pressure and vascular tone through nitric oxide metabolism in the vascular wall Molecular Signals Elicited by GPCR Agonists in Hypertension, Cardiovascular Remodeling: Are MMPs and ADAMs Elusive Therapeutic Targets?Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis.Phosphoinositide 3-kinase gamma regulates airway smooth muscle contraction by modulating calcium oscillations.Pertussis toxin nullifies the depolarization of the membrane potential and the stimulation of the rapid phase of Ca entry through L-type calcium channels that are produced by follicle stimulating hormone in 10- to 12-day-old rat Sertoli cells.Expression of microRNAs is essential for arterial myogenic tone and pressure-induced activation of the PI3-kinase/Akt pathway.Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney.PI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance.The Interplay between ROS and Ras GTPases: Physiological and Pathological Implications.Angiotensin II reduces food intake by altering orexigenic neuropeptide expression in the mouse hypothalamus.Angiotensin-(1-7)-mediated signaling in cardiomyocytes.Matrix metalloproteinase-9 deletion attenuates myocardial fibrosis and diastolic dysfunction in ageing mice Pressure Combined with Ischemia/Reperfusion Injury Induces Deep Tissue Injury via Endoplasmic Reticulum Stress in a Rat Pressure Ulcer Model.HIF isoforms in the skin differentially regulate systemic arterial pressure.Quercetin postconditioning attenuates myocardial ischemia/reperfusion injury in rats through the PI3K/Akt pathway.The cooperative roles of inflammation and oxidative stress in the pathogenesis of hypertension.Phosphoinositide 3-kinases and their role in inflammation: potential clinical targets in atherosclerosis?Specific PI3K isoform modulation in heart failure: lessons from transgenic mice.LOX-1 and angiotensin receptors, and their interplay.Molecular pathways linking metabolic inflammation and thermogenesis.Endothelial nitric oxide synthase, vascular integrity and human exceptional longevity.Therapeutic applications of PI3K inhibitors in cardiovascular diseases.High-Throughput RNAi Screening Identifies a Role for the Osteopontin Pathway in Proliferation and Migration of Human Aortic Smooth Muscle Cells.Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles.Angiotensin II stimulates phosphorylation of an ectodomain-truncated platelet-derived growth factor receptor-beta and its binding to class IA PI3K in vascular smooth muscle cells.Phosphatidylinositol 3-kinase-δ up-regulates L-type Ca2+ currents and increases vascular contractility in a mouse model of type 1 diabetes.Platelet-derived growth factor BB induces nuclear export and proteasomal degradation of CREB via phosphatidylinositol 3-kinase/Akt signaling in pulmonary artery smooth muscle cells.A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling.Involvement of phosphoinositide 3-kinase and PTEN protein in mechanism of activation of TRPC6 protein in vascular smooth muscle cells.Isoform-specific functions of phosphoinositide 3-kinases: p110 delta but not p110 gamma promotes optimal allergic responses in vivo Key role of PI3Kγ in monocyte chemotactic protein-1-mediated amplification of PDGF-induced aortic smooth muscle cell migration.Searching for transcriptional regulators of Ang II-induced vascular pathology.

P2860

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P2860

Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma.

http://www.wikidata.org/entity/Q36403518

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

Protection from angiotensin II ...... nse in mice lacking PI3Kgamma.

@ast

Protection from angiotensin II ...... nse in mice lacking PI3Kgamma.

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type

label

Protection from angiotensin II ...... nse in mice lacking PI3Kgamma.

@ast

Protection from angiotensin II ...... nse in mice lacking PI3Kgamma.

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prefLabel

Protection from angiotensin II ...... nse in mice lacking PI3Kgamma.

@ast

Protection from angiotensin II ...... nse in mice lacking PI3Kgamma.

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Journal of Experimental Medicine

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Protection from angiotensin II ...... nse in mice lacking PI3Kgamma.

@en

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Alessandra Aretini

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Angelo Maffei

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Carmine Vecchione

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Emilio Hirsch

http://www.w3.org/2001/XMLSchema#string

Enrico Patrucco

http://www.w3.org/2001/XMLSchema#string

Fiorella Altruda

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Gennaro Marino

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Gian Luca Colussi

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Giuseppe Lembo

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Guido Tarone

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P2860

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

Synthesis and function of 3-phosphorylated inositol lipids

A specific role of phosphatidylinositol 3-kinase gamma. A regulation of autonomic Ca(2)+ oscillations in cardiac cells

EGF receptor transactivation is obligatory for protein synthesis stimulation by G protein-coupled receptors

The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

NAD(P)H oxidase: role in cardiovascular biology and disease

Identification, distribution, and expression of angiotensin II receptors in the normal human prostate and benign prostatic hyperplasia.

Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases.

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

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1217-1228

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10.1084/JEM.20040995

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8

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201

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7912967

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15824082

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2213159

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