Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade. - Wikidata - awgldk - TriplyDB

Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade.

Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade.

http://www.wikidata.org/entity/Q36403583

about

Cytokines and cytokine profiles in human autoimmune diseases and animal models of autoimmunity Interleukin-1 in the pathogenesis and treatment of inflammatory diseases Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)Canakinumab Treating rheumatological diseases and co-morbidities with interleukin-1 blocking therapies Lighting the fires within: the cell biology of autoinflammatory diseases Treatment of juvenile idiopathic arthritis: a revolution in care Review: is there a window of opportunity for treatment of systemic juvenile idiopathic arthritis?Making sense of the cytokine storm: a conceptual framework for understanding, diagnosing, and treating hemophagocytic syndromes Beyond the NLRP3 inflammasome: autoinflammatory diseases reach adolescence Current concepts and future directions in the pathogenesis and treatment of non-infectious intraocular inflammation.IL-1 Inhibition in Systemic Juvenile Idiopathic Arthritis Juvenile Idiopathic Arthritis: Diagnosis and Treatment Evasion of inflammasome activation by microbial pathogens C13orf31 (FAMIN) is a central regulator of immunometabolic function Macrophage activation syndrome: advances towards understanding pathogenesis A transcriptomic reporter assay employing neutrophils to measure immunogenic activity of septic patients' plasma Biomarkers in systemic juvenile idiopathic arthritis: a comparison with biomarkers in cryopyrin-associated periodic syndromes An interactive web application for the dissemination of human systems immunology data Development of interleukin-1 receptor antagonist mutants with enhanced antagonistic activity in vitro and improved therapeutic efficacy in collagen-induced arthritis.Duration of chronic inflammation alters gene expression in muscle from untreated girls with juvenile dermatomyositis.Enhanced monocyte response and decreased central memory T cells in children with invasive Staphylococcus aureus infections Acute hepatitis in three patients with systemic juvenile idiopathic arthritis taking interleukin-1 receptor antagonist 2013 update of the 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: recommendations for the medical therapy of children with systemic juvenile idiopathic arthritis and tuberculosis screening a Blood gene expression profiling in pediatric systemic lupus erythematosus and systemic juvenile idiopathic arthritis: from bench to bedside.Assessing the human immune system through blood transcriptomics.Distribution of circulating cells in systemic juvenile idiopathic arthritis across disease activity states.Refining anti-inflammatory therapy strategies for bronchopulmonary dysplasia.Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity A genomic approach to human autoimmune diseases.What are the immunological consequences of long-term use of biological therapies for juvenile idiopathic arthritis?Toll-like receptor-mediated production of IL-1Ra is negatively regulated by GSK3 via the MAPK ERK1/2.Why not treat human cancer with interleukin-1 blockade?Safety and tolerability of the T-cell depletion protocol coupled with anakinra and etanercept for clinical islet cell transplantation.Role of IL-1 beta in the development of human T(H)17 cells: lesson from NLPR3 mutated patients.High expression of the ectonucleotidase CD39 on T cells from the inflamed site identifies two distinct populations, one regulatory and one memory T cell population Deregulation of the IL-1β axis in chronic recurrent multifocal osteomyelitis.Interleukin-17 regulation: an attractive therapeutic approach for asthma Monocytes are resistant to apoptosis in systemic juvenile idiopathic arthritis.Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1beta secretion.

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P2860

Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade.

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Edsel Arce

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Florence Allantaz

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Marilynn Punaro

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Virginia Pascual

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P2860

De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases

Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway

Interferon and granulopoiesis signatures in systemic lupus erythematosus blood

Long-term efficacy and safety of etanercept in children with polyarticular-course juvenile rheumatoid arthritis: interim results from an ongoing multicenter, open-label, extended-treatment trial.

Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist.

Combination therapy with etanercept and anakinra in the treatment of patients with rheumatoid arthritis who have been treated unsuccessfully with methotrexate.

Health status of patients with juvenile rheumatoid arthritis at 1 and 5 years after diagnosis.

CCR1 chemokine receptor antagonist.

The German etanercept registry for treatment of juvenile idiopathic arthritis.

Early predictors of outcome in juvenile idiopathic arthritis.

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